Matches in SemOpenAlex for { <https://semopenalex.org/work/W4364352011> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W4364352011 abstract "Background: An autoimmune inflammatory disease, rheumatoid arthritis (RA), predominantly affects the synovium joint lining, augmenting disability, early mortality, and socioeconomic difficulty. Therefore, current updates on pharmacological therapies are crucial for developing drugs to treat the disease at each stage. Objective: This review attempts to compile a thorough analysis of current developments in our knowledge of RA pathogenesis and disease-modifying drugs, with the aim of providing insights for next-generation RA therapeutics. Results: According to the literature, the most successful drugs for treatment techniques described so far in this include (cs) DMARDs (sub-class of DMARDs), tsDMARDS (targeted synthetic DMARDS), and bDMARDs (biological DMARDs). However, current pharmacologic therapy (consisting of biological, conventional, and creative views of small molecule anti-rheumatic drugs that treat the disease or DMARD) remains the cornerstone of rheumatoid arthritis treatment with which significant progress toward disease remission has been accomplished. Conclusion: The pathobiology of RA involves cytokine messengers such as B and T-cells, and an intricate interplay of pro-inflammatory cytokines responsible for activating and developing effector cells, in turn, accountable for local disease and systemic symptoms. Despite the fact that the cause of rheumatoid arthritis is not known, new treatments have been created as a result of better approaches towards the biology of the disease. As they target molecules directly implicated in the genesis of rheumatoid arthritis, these drugs may be more effective, targeted, and less harmful in the short and long term than standard therapies." @default.
- W4364352011 created "2023-04-12" @default.
- W4364352011 creator A5010815670 @default.
- W4364352011 creator A5016781101 @default.
- W4364352011 creator A5062686110 @default.
- W4364352011 creator A5084183451 @default.
- W4364352011 creator A5089657036 @default.
- W4364352011 date "2023-04-06" @default.
- W4364352011 modified "2023-09-26" @default.
- W4364352011 title "Current Prospects in Rheumatoid Arthritis: Pathophysiology, Genetics, and Treatments" @default.
- W4364352011 doi "https://doi.org/10.2174/2772434418666230406083149" @default.
- W4364352011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37038682" @default.
- W4364352011 hasPublicationYear "2023" @default.
- W4364352011 type Work @default.
- W4364352011 citedByCount "1" @default.
- W4364352011 countsByYear W43643520112023 @default.
- W4364352011 crossrefType "journal-article" @default.
- W4364352011 hasAuthorship W4364352011A5010815670 @default.
- W4364352011 hasAuthorship W4364352011A5016781101 @default.
- W4364352011 hasAuthorship W4364352011A5062686110 @default.
- W4364352011 hasAuthorship W4364352011A5084183451 @default.
- W4364352011 hasAuthorship W4364352011A5089657036 @default.
- W4364352011 hasConcept C126322002 @default.
- W4364352011 hasConcept C177713679 @default.
- W4364352011 hasConcept C203014093 @default.
- W4364352011 hasConcept C2777077863 @default.
- W4364352011 hasConcept C2777575956 @default.
- W4364352011 hasConcept C2779075594 @default.
- W4364352011 hasConcept C2779134260 @default.
- W4364352011 hasConcept C60644358 @default.
- W4364352011 hasConcept C71924100 @default.
- W4364352011 hasConcept C86803240 @default.
- W4364352011 hasConceptScore W4364352011C126322002 @default.
- W4364352011 hasConceptScore W4364352011C177713679 @default.
- W4364352011 hasConceptScore W4364352011C203014093 @default.
- W4364352011 hasConceptScore W4364352011C2777077863 @default.
- W4364352011 hasConceptScore W4364352011C2777575956 @default.
- W4364352011 hasConceptScore W4364352011C2779075594 @default.
- W4364352011 hasConceptScore W4364352011C2779134260 @default.
- W4364352011 hasConceptScore W4364352011C60644358 @default.
- W4364352011 hasConceptScore W4364352011C71924100 @default.
- W4364352011 hasConceptScore W4364352011C86803240 @default.
- W4364352011 hasLocation W43643520111 @default.
- W4364352011 hasLocation W43643520112 @default.
- W4364352011 hasOpenAccess W4364352011 @default.
- W4364352011 hasPrimaryLocation W43643520111 @default.
- W4364352011 hasRelatedWork W1964230165 @default.
- W4364352011 hasRelatedWork W1971296504 @default.
- W4364352011 hasRelatedWork W2098594117 @default.
- W4364352011 hasRelatedWork W2109765915 @default.
- W4364352011 hasRelatedWork W2129546463 @default.
- W4364352011 hasRelatedWork W2464711284 @default.
- W4364352011 hasRelatedWork W2950198226 @default.
- W4364352011 hasRelatedWork W4246884729 @default.
- W4364352011 hasRelatedWork W4313359005 @default.
- W4364352011 hasRelatedWork W98778818 @default.
- W4364352011 hasVolume "18" @default.
- W4364352011 isParatext "false" @default.
- W4364352011 isRetracted "false" @default.
- W4364352011 workType "article" @default.