Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365136331> ?p ?o ?g. }
- W4365136331 endingPage "573" @default.
- W4365136331 startingPage "565" @default.
- W4365136331 abstract "Alopecia areata is a heterogenous, immune-mediated hair loss disorder that can affect any hair-bearing site on the body. Despite being one of the most prevalent autoimmune skin diseases, treatments have historically been limited to off-label medications that have demonstrated limited efficacy, especially in more severe forms of disease. Thus, there has long been an unmet need for rigorously studied therapeutics in alopecia areata.Janus kinase inhibitors have proven to be an effective class of drugs for treating several inflammatory disorders. One such drug, baricitinib, has recently demonstrated significant hair regrowth in phase 2 and 3 alopecia areata trials. It has since become the first systemic therapy approved for treating severe alopecia areata. This review examines the role of Janus kinase pathways in alopecia areata's pathogenesis and the safety and efficacy of baricitinib for treating severe alopecia areata.The approval of baricitinib for treating severe alopecia areata marks a major milestone in the disease's history. While baricitinib has proven to be efficacious for this indication and has demonstrated an overall good safety profile, patients' individual risk factors for serious adverse events should be assessed during shared decision-making with patients before initiating treatment." @default.
- W4365136331 created "2023-04-13" @default.
- W4365136331 creator A5005373706 @default.
- W4365136331 creator A5020027481 @default.
- W4365136331 creator A5081914187 @default.
- W4365136331 date "2023-04-12" @default.
- W4365136331 modified "2023-09-26" @default.
- W4365136331 title "Baricitinib as the first systemic treatment for severe alopecia areata" @default.
- W4365136331 cites W1713940552 @default.
- W4365136331 cites W1975165863 @default.
- W4365136331 cites W1999468608 @default.
- W4365136331 cites W2015733931 @default.
- W4365136331 cites W2048162737 @default.
- W4365136331 cites W2049804077 @default.
- W4365136331 cites W2081460605 @default.
- W4365136331 cites W2095828085 @default.
- W4365136331 cites W2105110037 @default.
- W4365136331 cites W2106855185 @default.
- W4365136331 cites W2145607459 @default.
- W4365136331 cites W2163087340 @default.
- W4365136331 cites W2414073010 @default.
- W4365136331 cites W2521655245 @default.
- W4365136331 cites W2580870032 @default.
- W4365136331 cites W2595942898 @default.
- W4365136331 cites W2735384831 @default.
- W4365136331 cites W2766352046 @default.
- W4365136331 cites W2767923804 @default.
- W4365136331 cites W2773006631 @default.
- W4365136331 cites W2773759136 @default.
- W4365136331 cites W2800189296 @default.
- W4365136331 cites W2801012323 @default.
- W4365136331 cites W2804830550 @default.
- W4365136331 cites W2883519784 @default.
- W4365136331 cites W2883745911 @default.
- W4365136331 cites W2914096765 @default.
- W4365136331 cites W2918485751 @default.
- W4365136331 cites W2926411573 @default.
- W4365136331 cites W2978131730 @default.
- W4365136331 cites W2995517661 @default.
- W4365136331 cites W2995815572 @default.
- W4365136331 cites W3049657126 @default.
- W4365136331 cites W3105706486 @default.
- W4365136331 cites W3155379600 @default.
- W4365136331 cites W3171539837 @default.
- W4365136331 cites W3173232843 @default.
- W4365136331 cites W3176418240 @default.
- W4365136331 cites W3193748282 @default.
- W4365136331 cites W3196653406 @default.
- W4365136331 cites W3217308671 @default.
- W4365136331 cites W4211144854 @default.
- W4365136331 cites W4220744609 @default.
- W4365136331 cites W4220948160 @default.
- W4365136331 cites W4294622199 @default.
- W4365136331 cites W4296416904 @default.
- W4365136331 doi "https://doi.org/10.1080/1744666x.2023.2200166" @default.
- W4365136331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37042112" @default.
- W4365136331 hasPublicationYear "2023" @default.
- W4365136331 type Work @default.
- W4365136331 citedByCount "1" @default.
- W4365136331 countsByYear W43651363312023 @default.
- W4365136331 crossrefType "journal-article" @default.
- W4365136331 hasAuthorship W4365136331A5005373706 @default.
- W4365136331 hasAuthorship W4365136331A5020027481 @default.
- W4365136331 hasAuthorship W4365136331A5081914187 @default.
- W4365136331 hasConcept C112392421 @default.
- W4365136331 hasConcept C126322002 @default.
- W4365136331 hasConcept C16005928 @default.
- W4365136331 hasConcept C197934379 @default.
- W4365136331 hasConcept C203014093 @default.
- W4365136331 hasConcept C2776360568 @default.
- W4365136331 hasConcept C2777524370 @default.
- W4365136331 hasConcept C2778690821 @default.
- W4365136331 hasConcept C71924100 @default.
- W4365136331 hasConceptScore W4365136331C112392421 @default.
- W4365136331 hasConceptScore W4365136331C126322002 @default.
- W4365136331 hasConceptScore W4365136331C16005928 @default.
- W4365136331 hasConceptScore W4365136331C197934379 @default.
- W4365136331 hasConceptScore W4365136331C203014093 @default.
- W4365136331 hasConceptScore W4365136331C2776360568 @default.
- W4365136331 hasConceptScore W4365136331C2777524370 @default.
- W4365136331 hasConceptScore W4365136331C2778690821 @default.
- W4365136331 hasConceptScore W4365136331C71924100 @default.
- W4365136331 hasIssue "6" @default.
- W4365136331 hasLocation W43651363311 @default.
- W4365136331 hasLocation W43651363312 @default.
- W4365136331 hasOpenAccess W4365136331 @default.
- W4365136331 hasPrimaryLocation W43651363311 @default.
- W4365136331 hasRelatedWork W2548627709 @default.
- W4365136331 hasRelatedWork W2619840996 @default.
- W4365136331 hasRelatedWork W2977125940 @default.
- W4365136331 hasRelatedWork W3048144437 @default.
- W4365136331 hasRelatedWork W3072690337 @default.
- W4365136331 hasRelatedWork W3210636663 @default.
- W4365136331 hasRelatedWork W4205908659 @default.
- W4365136331 hasRelatedWork W4283267213 @default.
- W4365136331 hasRelatedWork W4285153522 @default.
- W4365136331 hasRelatedWork W4304014619 @default.
- W4365136331 hasVolume "19" @default.