Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365137016> ?p ?o ?g. }
- W4365137016 endingPage "553" @default.
- W4365137016 startingPage "539" @default.
- W4365137016 abstract "Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these species can stably and asymptomatically colonize human skin and gastrointestinal tracts. To consider these disparate microbial lifestyles, we first review factors shown to influence the underlying microbiome. Structured by the damage response framework, we then consider the molecular mechanisms deployed by C. albicans to switch between commensal and pathogenic lifestyles. Next, we explore this framework with C. auris to highlight how host physiology, immunity, and/or antibiotic receipt are associated with progression from colonization to infection. While treatment with antibiotics increases the risk that an individual will succumb to invasive candidiasis, the underlying mechanisms remain unclear. Here, we describe several hypotheses that may explain this phenomenon. We conclude by highlighting future directions integrating genomics with immunology to advance our understanding of invasive candidiasis and human fungal disease." @default.
- W4365137016 created "2023-04-13" @default.
- W4365137016 creator A5022799608 @default.
- W4365137016 creator A5037783335 @default.
- W4365137016 creator A5041537767 @default.
- W4365137016 creator A5082720864 @default.
- W4365137016 date "2023-04-01" @default.
- W4365137016 modified "2023-10-06" @default.
- W4365137016 title "One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome" @default.
- W4365137016 cites W1583831774 @default.
- W4365137016 cites W1593143946 @default.
- W4365137016 cites W1600809398 @default.
- W4365137016 cites W176297386 @default.
- W4365137016 cites W1918048000 @default.
- W4365137016 cites W1956380765 @default.
- W4365137016 cites W1973269610 @default.
- W4365137016 cites W1979435687 @default.
- W4365137016 cites W1981761407 @default.
- W4365137016 cites W1982958549 @default.
- W4365137016 cites W1985155016 @default.
- W4365137016 cites W1989525058 @default.
- W4365137016 cites W1990857438 @default.
- W4365137016 cites W1998653357 @default.
- W4365137016 cites W2002870035 @default.
- W4365137016 cites W2006561222 @default.
- W4365137016 cites W2012508946 @default.
- W4365137016 cites W2012600634 @default.
- W4365137016 cites W2027127354 @default.
- W4365137016 cites W2060216716 @default.
- W4365137016 cites W2061730726 @default.
- W4365137016 cites W2074335138 @default.
- W4365137016 cites W2087855047 @default.
- W4365137016 cites W2089867899 @default.
- W4365137016 cites W2090605607 @default.
- W4365137016 cites W2098976315 @default.
- W4365137016 cites W2100847237 @default.
- W4365137016 cites W2105256542 @default.
- W4365137016 cites W2107447381 @default.
- W4365137016 cites W2116516945 @default.
- W4365137016 cites W2135996875 @default.
- W4365137016 cites W2137019479 @default.
- W4365137016 cites W2156117266 @default.
- W4365137016 cites W2160578994 @default.
- W4365137016 cites W2161185537 @default.
- W4365137016 cites W2162303211 @default.
- W4365137016 cites W2163945813 @default.
- W4365137016 cites W2164678669 @default.
- W4365137016 cites W2168373615 @default.
- W4365137016 cites W2170646563 @default.
- W4365137016 cites W2171197491 @default.
- W4365137016 cites W2279293317 @default.
- W4365137016 cites W2329943654 @default.
- W4365137016 cites W2396765784 @default.
- W4365137016 cites W2477520558 @default.
- W4365137016 cites W2514801655 @default.
- W4365137016 cites W2521042841 @default.
- W4365137016 cites W2536287248 @default.
- W4365137016 cites W2538799985 @default.
- W4365137016 cites W2547589532 @default.
- W4365137016 cites W2605788558 @default.
- W4365137016 cites W2616380171 @default.
- W4365137016 cites W2744057697 @default.
- W4365137016 cites W2747509320 @default.
- W4365137016 cites W2761761695 @default.
- W4365137016 cites W2770664545 @default.
- W4365137016 cites W2771149562 @default.
- W4365137016 cites W2774082186 @default.
- W4365137016 cites W2774868879 @default.
- W4365137016 cites W2779247488 @default.
- W4365137016 cites W2784164089 @default.
- W4365137016 cites W2797413896 @default.
- W4365137016 cites W2800418943 @default.
- W4365137016 cites W2801640552 @default.
- W4365137016 cites W2808030776 @default.
- W4365137016 cites W2889392906 @default.
- W4365137016 cites W2890220120 @default.
- W4365137016 cites W2894384327 @default.
- W4365137016 cites W2895137000 @default.
- W4365137016 cites W2895141223 @default.
- W4365137016 cites W2896989720 @default.
- W4365137016 cites W2899480717 @default.
- W4365137016 cites W2912140333 @default.
- W4365137016 cites W2915525319 @default.
- W4365137016 cites W2916088628 @default.
- W4365137016 cites W2921726164 @default.
- W4365137016 cites W2922073341 @default.
- W4365137016 cites W2922478983 @default.
- W4365137016 cites W2947662217 @default.
- W4365137016 cites W2986170840 @default.
- W4365137016 cites W2996168925 @default.
- W4365137016 cites W2997426704 @default.
- W4365137016 cites W2999046918 @default.
- W4365137016 cites W3000095198 @default.
- W4365137016 cites W3014384057 @default.
- W4365137016 cites W3037766364 @default.
- W4365137016 cites W3084464652 @default.
- W4365137016 cites W3111518718 @default.
- W4365137016 cites W3114762667 @default.