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- W4365138535 abstract "Abstract BACKGROUND : Bartonella henselae are intracellular bacteria transmitted to humans through animal bites and scratches contaminated with the feces of arthropod vectors, and are most commonly associated with cat exposure although transmission from other mammals has been reported. Bartonella henselae infection has a spectrum of clinical manifestations and has rarely been reported as cause of hemophagocytic lymphohistiocytosis (HLH) in immunocompromised hosts. CASE PRESENTATION: We present a report of Bartonella henselae infection progressing to HLH in an immunocompetent host. The patient initially presented with regional lymphadenopathy but the diagnosis was not suspected as the patient reported no exposure to cats. On further history, he did report a scratch from a dog prior to development of symptoms. The patient was treated with methylprednisolone, intravenous immunoglobulin and anakinra for the HLH and three months of Doxycycline for Bartonella infection, with complete resolution of symptoms. CONCLUSIONS : Although commonly associated with cat exposure, Bartonella henselae transmission can occur after exposure to other animals including dogs and clinicians need to maintain an index of suspicion for timely diagnosis. Bartonella henselae is associated with a spectrum of clinical manifestations which can include disseminated infection with severe complications such as hemophagocytic lymphohistiocytosis. Prompt initiation of Bartonella treatment is essential when thought to be the trigger for hemophagocytic lymphohistiocytosis although the optimal treatment regimen is unclear." @default.
- W4365138535 created "2023-04-13" @default.
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- W4365138535 date "2023-04-12" @default.
- W4365138535 modified "2023-10-18" @default.
- W4365138535 title "Hemophagocytic lymphohistiocytosis secondary to unrecognized Bartonella henselae infection: A Case report " @default.
- W4365138535 doi "https://doi.org/10.21203/rs.3.rs-2783258/v1" @default.
- W4365138535 hasPublicationYear "2023" @default.
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