Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365149042> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4365149042 abstract "Matrix-enhanced secondary ion mass spectrometry (ME-SIMS) is an effective pre-treatment method for the sensitivity enhancement of large molecules. Recently, matrix-assisted laser desorption/ionization (MALDI) matrices, which consist of aromatic acids with benzene rings, have been developed using this technique. However, there are several differences in the desorption and ionization processes of SIMS and MALDI. In this study, the sensitivities of phospholipids mixed with aliphatic carboxylic acids were investigated using Bi-cluster time-of-flight SIMS (TOF-SIMS). Trans-aconitic acid (tri-carboxylic acid) and citric acid (hydroxycarboxylic acid) were used as the matrices. 2,5-Dihydroxybenzoic acid (DHB), which is a typical aromatic MALDI matrix, was selected as the reference matrix. When trans-aconitic acid and DHB were used as matrices, the secondary ion yields of [M + H]+ and [2 M + H]+ for phospholipids were approximately 10–150 times higher than that of the pristine lipid. For samples with citric acid, the yield enhancements of [M + H]+ and [2 M + H]+ were approximately 400–1000 times higher than those of pristine lipids. Furthermore, the protonated ionization of citric acid was mostly suppressed because of mixture with phospholipids. These results indicate that the matrix effect between phospholipids and the matrix contributes to the sensitivity enhancement of the target molecules. Hence, aliphatic carboxylic acid was equally or more effective than the MALDI matrix for the sensitivity enhancement of phospholipids in Bi-cluster TOF-SIMS." @default.
- W4365149042 created "2023-04-13" @default.
- W4365149042 creator A5042514000 @default.
- W4365149042 date "2023-04-17" @default.
- W4365149042 modified "2023-09-30" @default.
- W4365149042 title "Matrix‐enhanced secondary ion mass spectrometry: Effects of aliphatic carboxylic acid matrices on the sensitivity enhancement of biological phospholipids" @default.
- W4365149042 cites W1967073420 @default.
- W4365149042 cites W1972182593 @default.
- W4365149042 cites W1974507028 @default.
- W4365149042 cites W2001281545 @default.
- W4365149042 cites W2017035850 @default.
- W4365149042 cites W2028065165 @default.
- W4365149042 cites W2034553612 @default.
- W4365149042 cites W2043224118 @default.
- W4365149042 cites W2052326125 @default.
- W4365149042 cites W2059733215 @default.
- W4365149042 cites W2065657816 @default.
- W4365149042 cites W2132882085 @default.
- W4365149042 cites W2134295132 @default.
- W4365149042 cites W2275716855 @default.
- W4365149042 cites W2277705277 @default.
- W4365149042 cites W2316693625 @default.
- W4365149042 cites W3015473480 @default.
- W4365149042 cites W3025881747 @default.
- W4365149042 cites W3128679445 @default.
- W4365149042 cites W3198565174 @default.
- W4365149042 cites W4240811803 @default.
- W4365149042 cites W4251700885 @default.
- W4365149042 doi "https://doi.org/10.1002/sia.7212" @default.
- W4365149042 hasPublicationYear "2023" @default.
- W4365149042 type Work @default.
- W4365149042 citedByCount "1" @default.
- W4365149042 countsByYear W43651490422023 @default.
- W4365149042 crossrefType "journal-article" @default.
- W4365149042 hasAuthorship W4365149042A5042514000 @default.
- W4365149042 hasConcept C106487976 @default.
- W4365149042 hasConcept C113196181 @default.
- W4365149042 hasConcept C145148216 @default.
- W4365149042 hasConcept C150394285 @default.
- W4365149042 hasConcept C162356407 @default.
- W4365149042 hasConcept C162711632 @default.
- W4365149042 hasConcept C178790620 @default.
- W4365149042 hasConcept C185592680 @default.
- W4365149042 hasConcept C198291218 @default.
- W4365149042 hasConcept C2779032678 @default.
- W4365149042 hasConcept C2779074116 @default.
- W4365149042 hasConcept C30095370 @default.
- W4365149042 hasConcept C43617362 @default.
- W4365149042 hasConcept C75280812 @default.
- W4365149042 hasConcept C77671233 @default.
- W4365149042 hasConceptScore W4365149042C106487976 @default.
- W4365149042 hasConceptScore W4365149042C113196181 @default.
- W4365149042 hasConceptScore W4365149042C145148216 @default.
- W4365149042 hasConceptScore W4365149042C150394285 @default.
- W4365149042 hasConceptScore W4365149042C162356407 @default.
- W4365149042 hasConceptScore W4365149042C162711632 @default.
- W4365149042 hasConceptScore W4365149042C178790620 @default.
- W4365149042 hasConceptScore W4365149042C185592680 @default.
- W4365149042 hasConceptScore W4365149042C198291218 @default.
- W4365149042 hasConceptScore W4365149042C2779032678 @default.
- W4365149042 hasConceptScore W4365149042C2779074116 @default.
- W4365149042 hasConceptScore W4365149042C30095370 @default.
- W4365149042 hasConceptScore W4365149042C43617362 @default.
- W4365149042 hasConceptScore W4365149042C75280812 @default.
- W4365149042 hasConceptScore W4365149042C77671233 @default.
- W4365149042 hasLocation W43651490421 @default.
- W4365149042 hasOpenAccess W4365149042 @default.
- W4365149042 hasPrimaryLocation W43651490421 @default.
- W4365149042 hasRelatedWork W1976674493 @default.
- W4365149042 hasRelatedWork W1984005343 @default.
- W4365149042 hasRelatedWork W2069647888 @default.
- W4365149042 hasRelatedWork W2077151206 @default.
- W4365149042 hasRelatedWork W2145852303 @default.
- W4365149042 hasRelatedWork W2312679062 @default.
- W4365149042 hasRelatedWork W2320691067 @default.
- W4365149042 hasRelatedWork W327974415 @default.
- W4365149042 hasRelatedWork W4220916081 @default.
- W4365149042 hasRelatedWork W4365149042 @default.
- W4365149042 isParatext "false" @default.
- W4365149042 isRetracted "false" @default.
- W4365149042 workType "article" @default.