FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365450176> ?p ?o ?g. }

• W4365450176 abstract "Abstract Aging is an inevitable process of cellular and physiological decline. These markers of age can be measured on the molecular and functional level. Wearable devices offer a non-invasive continuous measure of physiological and behavioural features and how they pertain to aging. Wearable data can be used to extrapolate information derived from epigenetic biological age predictions and its underlying biology. LifeQ-enabled wearable devices were worn for 40 days to harvest data on 48 human participants. Thereafter blood was drawn and methylation levels determined using the Illumina EPIC array. Multiple epigenetic clock ages were calculated and compared with wearable features. Activity minutes correlated with VO 2 max (p = 0.003), subendocardial viability ratio (SEVR, p < 0.01), blood pressure index (BPI, p = 0.02), resting heart rate (RHR, p < 0.01) and heart outflow (HO, p < 0.01). Sedentary time correlated with RHR (p < 0.01), VO 2 max (p = 0.01), SEVR (p = 0.04), and HO (p = 0.04). VO 2 max, SEVR, small artery resistance (SAR), BPI and large artery stiffness index (LASI) correlated with multiple epigenetic age clock outputs and chronological age but were most strongly correlated with PCPhenoAge. VO 2 max, (p = 0.04) RHR (p < 0.01) and LASI (p = 0.04) were significantly correlated with PCPhenoAge acceleration. Weighted gene correlation network analysis (WGCNA) of the differentially methylated positions of PCPhenoAge acceleration was used to construct modules, identifying 3 modules correlating with wearable features. Behavioural features impact physiological state, measured by the wearable, which are associated with epigenetic age and age acceleration. Signal from the underlying biology of age acceleration can be picked up by the wearable, presenting a case that wearable devices can capture portions of biological aging." @default.
• W4365450176 created "2023-04-15" @default.
• W4365450176 creator A5022911299 @default.
• W4365450176 creator A5060026318 @default.
• W4365450176 creator A5070984946 @default.
• W4365450176 creator A5071543460 @default.
• W4365450176 date "2023-04-13" @default.
• W4365450176 modified "2023-10-17" @default.
• W4365450176 title "Wearable-ome meets epigenome: A novel approach to measuring biological age with wearable devices" @default.
• W4365450176 cites W1583921993 @default.
• W4365450176 cites W1590047728 @default.
• W4365450176 cites W1966327575 @default.
• W4365450176 cites W1974047233 @default.
• W4365450176 cites W1989674299 @default.
• W4365450176 cites W2006251119 @default.
• W4365450176 cites W2015361145 @default.
• W4365450176 cites W2036284273 @default.
• W4365450176 cites W2038429516 @default.
• W4365450176 cites W2046647351 @default.
• W4365450176 cites W2048376025 @default.
• W4365450176 cites W2058794316 @default.
• W4365450176 cites W2060705109 @default.
• W4365450176 cites W2063913875 @default.
• W4365450176 cites W2083872334 @default.
• W4365450176 cites W2102872833 @default.
• W4365450176 cites W2110552101 @default.
• W4365450176 cites W2115826902 @default.
• W4365450176 cites W2121091193 @default.
• W4365450176 cites W2126525177 @default.
• W4365450176 cites W2127431419 @default.
• W4365450176 cites W2134613826 @default.
• W4365450176 cites W2138673074 @default.
• W4365450176 cites W2170165809 @default.
• W4365450176 cites W2202178422 @default.
• W4365450176 cites W2232156689 @default.
• W4365450176 cites W2323824056 @default.
• W4365450176 cites W2397668368 @default.
• W4365450176 cites W2529963495 @default.
• W4365450176 cites W2563261415 @default.
• W4365450176 cites W2590469096 @default.
• W4365450176 cites W2609954126 @default.
• W4365450176 cites W2784666693 @default.
• W4365450176 cites W2796470921 @default.
• W4365450176 cites W2796559433 @default.
• W4365450176 cites W2811113171 @default.
• W4365450176 cites W2811354364 @default.
• W4365450176 cites W2902406001 @default.
• W4365450176 cites W2912654909 @default.
• W4365450176 cites W2948309327 @default.
• W4365450176 cites W2949129901 @default.
• W4365450176 cites W2965579739 @default.
• W4365450176 cites W2974802259 @default.
• W4365450176 cites W2988906435 @default.
• W4365450176 cites W2990131872 @default.
• W4365450176 cites W2998051599 @default.
• W4365450176 cites W2999339913 @default.
• W4365450176 cites W3000301202 @default.
• W4365450176 cites W3011777860 @default.
• W4365450176 cites W3015068997 @default.
• W4365450176 cites W3022241140 @default.
• W4365450176 cites W3023925757 @default.
• W4365450176 cites W3040750692 @default.
• W4365450176 cites W3046797531 @default.
• W4365450176 cites W3103367485 @default.
• W4365450176 cites W3159164156 @default.
• W4365450176 cites W3183860080 @default.
• W4365450176 cites W3209368216 @default.
• W4365450176 cites W3209385840 @default.
• W4365450176 cites W4200587590 @default.
• W4365450176 cites W4210753636 @default.
• W4365450176 cites W4225270242 @default.
• W4365450176 cites W4225270271 @default.
• W4365450176 cites W4232181702 @default.
• W4365450176 cites W4295066373 @default.
• W4365450176 cites W4295901033 @default.
• W4365450176 cites W4315705280 @default.
• W4365450176 cites W4319461930 @default.
• W4365450176 doi "https://doi.org/10.1101/2023.04.11.536462" @default.
• W4365450176 hasPublicationYear "2023" @default.
• W4365450176 type Work @default.
• W4365450176 citedByCount "0" @default.
• W4365450176 crossrefType "posted-content" @default.
• W4365450176 hasAuthorship W4365450176A5022911299 @default.
• W4365450176 hasAuthorship W4365450176A5060026318 @default.
• W4365450176 hasAuthorship W4365450176A5070984946 @default.
• W4365450176 hasAuthorship W4365450176A5071543460 @default.
• W4365450176 hasBestOaLocation W43654501761 @default.
• W4365450176 hasConcept C104317684 @default.
• W4365450176 hasConcept C117717151 @default.
• W4365450176 hasConcept C126322002 @default.
• W4365450176 hasConcept C149635348 @default.
• W4365450176 hasConcept C150194340 @default.
• W4365450176 hasConcept C150594956 @default.
• W4365450176 hasConcept C190727270 @default.
• W4365450176 hasConcept C2777953023 @default.
• W4365450176 hasConcept C41008148 @default.
• W4365450176 hasConcept C41091548 @default.
• W4365450176 hasConcept C54355233 @default.
• W4365450176 hasConcept C60644358 @default.
• W4365450176 hasConcept C71924100 @default.

• next