Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365505677> ?p ?o ?g. }
- W4365505677 abstract "Abstract Abnormalities pertaining to glycoconjugates (glycoproteins, proteoglycans, and glycolipids) of the neural extracellular matrix have been identified as a susceptibility factor in autism spectrum disorder. We studied the urine excretion of sulfated glycosaminoglycans in children with autism spectrum disorder (n=61), in comparison to age- and sex-matched neurotypical controls (n=61). Urine glycosaminoglycan levels were determined in random urine samples by the dimethylmethylene blue (DMMB) dye-binding assay, using a microplate reader. Urine GAG levels are significantly higher (p = 0.026) in the ASD group when covariates such as age, weight, urinary creatinine, and height are taken into consideration by ANCOVA. In neurotypical subjects, the urine glycosaminoglycan levels appear to decline with age, height, and weight while this trend was not apparent in subjects with autism spectrum disorder. Glycosaminoglycan excretion did not correlate with the presence of co-occurring symptoms of autism spectrum disorder; frequent gastrointestinal symptoms, self-injurious behaviors, food aversions, or parent-reported sleep problems. Children with autism spectrum disorder exhibit higher urine glycosaminoglycan excretion. Further research is needed to identify its correlation with severity and genetic factors and other metabotypes." @default.
- W4365505677 created "2023-04-15" @default.
- W4365505677 creator A5003725112 @default.
- W4365505677 creator A5012187740 @default.
- W4365505677 creator A5013018491 @default.
- W4365505677 creator A5016905751 @default.
- W4365505677 creator A5018683438 @default.
- W4365505677 creator A5030541212 @default.
- W4365505677 creator A5049623669 @default.
- W4365505677 date "2023-04-14" @default.
- W4365505677 modified "2023-09-30" @default.
- W4365505677 title "Comparison of urine glycosaminoglycan excretion between children with autism spectrum disorder and typically developed children" @default.
- W4365505677 cites W1482695305 @default.
- W4365505677 cites W185449676 @default.
- W4365505677 cites W1909050132 @default.
- W4365505677 cites W1930879781 @default.
- W4365505677 cites W1978591633 @default.
- W4365505677 cites W1982042883 @default.
- W4365505677 cites W2019428611 @default.
- W4365505677 cites W2023285159 @default.
- W4365505677 cites W2039255263 @default.
- W4365505677 cites W2067104230 @default.
- W4365505677 cites W2076055965 @default.
- W4365505677 cites W2092334401 @default.
- W4365505677 cites W2103887178 @default.
- W4365505677 cites W2107083291 @default.
- W4365505677 cites W2110143479 @default.
- W4365505677 cites W2114967127 @default.
- W4365505677 cites W2155465918 @default.
- W4365505677 cites W2167943688 @default.
- W4365505677 cites W2169984491 @default.
- W4365505677 cites W2333127890 @default.
- W4365505677 cites W2342362047 @default.
- W4365505677 cites W2389559473 @default.
- W4365505677 cites W2460384431 @default.
- W4365505677 cites W2461269455 @default.
- W4365505677 cites W2526629344 @default.
- W4365505677 cites W2555361771 @default.
- W4365505677 cites W2750453805 @default.
- W4365505677 cites W2761793213 @default.
- W4365505677 cites W2775647200 @default.
- W4365505677 cites W2913540820 @default.
- W4365505677 cites W2943088522 @default.
- W4365505677 cites W2959289532 @default.
- W4365505677 cites W3003997294 @default.
- W4365505677 cites W3005182523 @default.
- W4365505677 cites W3011266331 @default.
- W4365505677 cites W3011465337 @default.
- W4365505677 cites W3012794949 @default.
- W4365505677 cites W3023344856 @default.
- W4365505677 cites W3037150233 @default.
- W4365505677 cites W3119115535 @default.
- W4365505677 cites W3122442351 @default.
- W4365505677 cites W3130922945 @default.
- W4365505677 cites W3133979563 @default.
- W4365505677 cites W3160995530 @default.
- W4365505677 cites W3171928187 @default.
- W4365505677 cites W3209293255 @default.
- W4365505677 cites W3209661487 @default.
- W4365505677 cites W4214663068 @default.
- W4365505677 cites W4221054645 @default.
- W4365505677 cites W4247665917 @default.
- W4365505677 cites W4284962360 @default.
- W4365505677 doi "https://doi.org/10.21203/rs.3.rs-2810930/v1" @default.
- W4365505677 hasPublicationYear "2023" @default.
- W4365505677 type Work @default.
- W4365505677 citedByCount "0" @default.
- W4365505677 crossrefType "posted-content" @default.
- W4365505677 hasAuthorship W4365505677A5003725112 @default.
- W4365505677 hasAuthorship W4365505677A5012187740 @default.
- W4365505677 hasAuthorship W4365505677A5013018491 @default.
- W4365505677 hasAuthorship W4365505677A5016905751 @default.
- W4365505677 hasAuthorship W4365505677A5018683438 @default.
- W4365505677 hasAuthorship W4365505677A5030541212 @default.
- W4365505677 hasAuthorship W4365505677A5049623669 @default.
- W4365505677 hasBestOaLocation W43655056771 @default.
- W4365505677 hasConcept C10146269 @default.
- W4365505677 hasConcept C118552586 @default.
- W4365505677 hasConcept C126322002 @default.
- W4365505677 hasConcept C134018914 @default.
- W4365505677 hasConcept C153074725 @default.
- W4365505677 hasConcept C15744967 @default.
- W4365505677 hasConcept C185592680 @default.
- W4365505677 hasConcept C205778803 @default.
- W4365505677 hasConcept C2778538070 @default.
- W4365505677 hasConcept C2780026642 @default.
- W4365505677 hasConcept C55493867 @default.
- W4365505677 hasConcept C71924100 @default.
- W4365505677 hasConceptScore W4365505677C10146269 @default.
- W4365505677 hasConceptScore W4365505677C118552586 @default.
- W4365505677 hasConceptScore W4365505677C126322002 @default.
- W4365505677 hasConceptScore W4365505677C134018914 @default.
- W4365505677 hasConceptScore W4365505677C153074725 @default.
- W4365505677 hasConceptScore W4365505677C15744967 @default.
- W4365505677 hasConceptScore W4365505677C185592680 @default.
- W4365505677 hasConceptScore W4365505677C205778803 @default.
- W4365505677 hasConceptScore W4365505677C2778538070 @default.
- W4365505677 hasConceptScore W4365505677C2780026642 @default.
- W4365505677 hasConceptScore W4365505677C55493867 @default.
- W4365505677 hasConceptScore W4365505677C71924100 @default.