FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365514152> ?p ?o ?g. }

• W4365514152 abstract "Epithelial ovarian cancer (EOC) is one of the most fatal gynecological malignancies among elderly patients. We aim to construct two nomograms to predict the overall survival (OS) and cancer-specific survival (CSS) in elderly EOC patients.Elderly patients with EOC between 2000 and 2019 were selected from the Surveillance, Epidemiology, and End Results (SEER) database. Enrolled patients were randomly divided into the training and validation set at a ratio of 2:1. The OS and CSS were recognized as endpoint times. The independent prognostic factors from the multivariate analysis were used to establish nomograms for predicting the 3-, 5- and 10-year OS and CSS of elderly EOC patients. The improvement of predictive ability and clinical benefits were evaluated by consistency index (C-index), receiver operating characteristic (ROC), calibration curve, decision curve (DCA), net reclassification improvement (NRI), and integrated discrimination improvement (IDI). Finally, the treatment efficacy of surgery and chemotherapy in low-, medium-, and high-risk groups were displayed by Kaplan-Meier curves.Five thousand five hundred eighty-eight elderly EOC patients were obtained and randomly assigned to the training set (n = 3724) and validation set (n = 1864). The independent prognostic factors were utilized to construct nomograms for OS and CSS. Dynamic nomograms were also developed. The C-index of the OS nomogram and CSS nomogram were 0.713 and 0.729 in the training cohort. In the validation cohort, the C-index of the OS nomogram and CSS nomogram were 0.751 and 0.702. The calibration curve demonstrated good concordance between the predicted survival rates and actual observations. Moreover, the NRI, IDI, and DCA curves determined the outperformance of the nomogram compared with the AJCC stage system. Besides, local tumor resection had a higher benefit on the prognosis in all patients. Chemotherapy had a better prognosis in the high-risk groups, but not for the medium- risk and low-risk groups.We developed and validated nomograms for predicting OS and CSS in elderly EOC patients to help gynecologists to develop an appropriate individualized therapeutic schedule." @default.
• W4365514152 created "2023-04-15" @default.
• W4365514152 creator A5010967019 @default.
• W4365514152 creator A5031810848 @default.
• W4365514152 creator A5034954771 @default.
• W4365514152 creator A5039998840 @default.
• W4365514152 creator A5048760712 @default.
• W4365514152 creator A5060281157 @default.
• W4365514152 creator A5066680473 @default.
• W4365514152 creator A5072934731 @default.
• W4365514152 creator A5076903478 @default.
• W4365514152 date "2023-04-14" @default.
• W4365514152 modified "2023-10-14" @default.
• W4365514152 title "Nomograms for predicting overall survival and cancer-specific survival in elderly patients with epithelial ovarian cancer" @default.
• W4365514152 cites W1152011753 @default.
• W4365514152 cites W1966932597 @default.
• W4365514152 cites W2006135526 @default.
• W4365514152 cites W2014623932 @default.
• W4365514152 cites W2085116144 @default.
• W4365514152 cites W2153505392 @default.
• W4365514152 cites W2334202086 @default.
• W4365514152 cites W2624040118 @default.
• W4365514152 cites W2769374082 @default.
• W4365514152 cites W2801256833 @default.
• W4365514152 cites W2808700395 @default.
• W4365514152 cites W2810268451 @default.
• W4365514152 cites W2894372119 @default.
• W4365514152 cites W2904073034 @default.
• W4365514152 cites W2949079945 @default.
• W4365514152 cites W2968668807 @default.
• W4365514152 cites W3025767973 @default.
• W4365514152 cites W3092758847 @default.
• W4365514152 cites W3191198941 @default.
• W4365514152 cites W3209814135 @default.
• W4365514152 cites W3214757208 @default.
• W4365514152 cites W4206841660 @default.
• W4365514152 cites W4211030512 @default.
• W4365514152 cites W4211247697 @default.
• W4365514152 cites W4220842663 @default.
• W4365514152 cites W4221065330 @default.
• W4365514152 cites W4225845169 @default.
• W4365514152 doi "https://doi.org/10.1186/s13048-023-01144-y" @default.
• W4365514152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37059991" @default.
• W4365514152 hasPublicationYear "2023" @default.
• W4365514152 type Work @default.
• W4365514152 citedByCount "1" @default.
• W4365514152 countsByYear W43655141522023 @default.
• W4365514152 crossrefType "journal-article" @default.
• W4365514152 hasAuthorship W4365514152A5010967019 @default.
• W4365514152 hasAuthorship W4365514152A5031810848 @default.
• W4365514152 hasAuthorship W4365514152A5034954771 @default.
• W4365514152 hasAuthorship W4365514152A5039998840 @default.
• W4365514152 hasAuthorship W4365514152A5048760712 @default.
• W4365514152 hasAuthorship W4365514152A5060281157 @default.
• W4365514152 hasAuthorship W4365514152A5066680473 @default.
• W4365514152 hasAuthorship W4365514152A5072934731 @default.
• W4365514152 hasAuthorship W4365514152A5076903478 @default.
• W4365514152 hasBestOaLocation W43655141521 @default.
• W4365514152 hasConcept C121608353 @default.
• W4365514152 hasConcept C126322002 @default.
• W4365514152 hasConcept C143998085 @default.
• W4365514152 hasConcept C160798450 @default.
• W4365514152 hasConcept C2780427987 @default.
• W4365514152 hasConcept C34626388 @default.
• W4365514152 hasConcept C38180746 @default.
• W4365514152 hasConcept C58471807 @default.
• W4365514152 hasConcept C71924100 @default.
• W4365514152 hasConcept C72563966 @default.
• W4365514152 hasConceptScore W4365514152C121608353 @default.
• W4365514152 hasConceptScore W4365514152C126322002 @default.
• W4365514152 hasConceptScore W4365514152C143998085 @default.
• W4365514152 hasConceptScore W4365514152C160798450 @default.
• W4365514152 hasConceptScore W4365514152C2780427987 @default.
• W4365514152 hasConceptScore W4365514152C34626388 @default.
• W4365514152 hasConceptScore W4365514152C38180746 @default.
• W4365514152 hasConceptScore W4365514152C58471807 @default.
• W4365514152 hasConceptScore W4365514152C71924100 @default.
• W4365514152 hasConceptScore W4365514152C72563966 @default.
• W4365514152 hasIssue "1" @default.
• W4365514152 hasLocation W43655141521 @default.
• W4365514152 hasLocation W43655141522 @default.
• W4365514152 hasLocation W43655141523 @default.
• W4365514152 hasLocation W43655141524 @default.
• W4365514152 hasOpenAccess W4365514152 @default.
• W4365514152 hasPrimaryLocation W43655141521 @default.
• W4365514152 hasRelatedWork W3046914435 @default.
• W4365514152 hasRelatedWork W3095136102 @default.
• W4365514152 hasRelatedWork W3190029335 @default.
• W4365514152 hasRelatedWork W4292454933 @default.
• W4365514152 hasRelatedWork W4296065509 @default.
• W4365514152 hasRelatedWork W4310352383 @default.
• W4365514152 hasRelatedWork W4317891105 @default.
• W4365514152 hasRelatedWork W4383896453 @default.
• W4365514152 hasRelatedWork W4384924049 @default.
• W4365514152 hasRelatedWork W4385064084 @default.
• W4365514152 hasVolume "16" @default.
• W4365514152 isParatext "false" @default.
• W4365514152 isRetracted "false" @default.
• W4365514152 workType "article" @default.