FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365514687> ?p ?o ?g. }

• W4365514687 abstract "Objective : To systematically evaluate the efficacy of mesenchymal stem cells (MSCs) for acute kidney injury (AKI) in preclinical studies and to explore the optimal transplantation strategy of MSCs by network meta-analysis with the aim of improving the efficacy of stem cell therapy. Methods : Computer searches of PubMed, Web of Science, Cochrane, Embase, CNKI, Wanfang, VIP, and CBM databases were conducted until 17 August 2022. Literature screening, data extraction and quality evaluation were performed independently by two researchers. Results and Discussion : A total of 50 randomized controlled animal studies were included. The results of traditional meta-analysis showed that MSCs could significantly improve the renal function and injured renal tissue of AKI rats in different subgroups. The results of network meta-analysis showed that although there was no significant difference in the therapeutic effect between different transplant routes and doses of MSCs, the results of surface under the cumulative ranking probability curve (SUCRA) showed that the therapeutic effect of intravenous transplantation of MSCs was better than that of arterial and intrarenal transplantation, and the therapeutic effect of high dose (&gt;1×10 6 ) was better than that of low dose (≤1×10 6 ). However, the current preclinical studies have limitations in experimental design, measurement and reporting of results, and more high-quality studies, especially direct comparative evidence, are needed in the future to further confirm the best transplantation strategy of MSCs in AKI. Systematic Review Registration: identifier https://CRD42022361199 , https://www.crd.york.ac.uk/prospero ." @default.
• W4365514687 created "2023-04-15" @default.
• W4365514687 creator A5006822602 @default.
• W4365514687 creator A5024629778 @default.
• W4365514687 creator A5055650881 @default.
• W4365514687 creator A5066716873 @default.
• W4365514687 creator A5073335728 @default.
• W4365514687 creator A5090907351 @default.
• W4365514687 date "2023-04-13" @default.
• W4365514687 modified "2023-10-03" @default.
• W4365514687 title "Mesenchymal stem cells therapy for acute kidney injury: A systematic review with meta-analysis based on rat model" @default.
• W4365514687 cites W1489794536 @default.
• W4365514687 cites W1499722362 @default.
• W4365514687 cites W174053740 @default.
• W4365514687 cites W1967237937 @default.
• W4365514687 cites W1983026013 @default.
• W4365514687 cites W1983450788 @default.
• W4365514687 cites W1994634932 @default.
• W4365514687 cites W1995445609 @default.
• W4365514687 cites W1998066488 @default.
• W4365514687 cites W2001470198 @default.
• W4365514687 cites W2003500862 @default.
• W4365514687 cites W2004026285 @default.
• W4365514687 cites W2018091219 @default.
• W4365514687 cites W2045705524 @default.
• W4365514687 cites W2048834102 @default.
• W4365514687 cites W2050377594 @default.
• W4365514687 cites W2053134443 @default.
• W4365514687 cites W2058571677 @default.
• W4365514687 cites W2060754957 @default.
• W4365514687 cites W2062960367 @default.
• W4365514687 cites W2071904806 @default.
• W4365514687 cites W2074219405 @default.
• W4365514687 cites W2077967941 @default.
• W4365514687 cites W2082373522 @default.
• W4365514687 cites W2085236986 @default.
• W4365514687 cites W2092810335 @default.
• W4365514687 cites W2100648382 @default.
• W4365514687 cites W2101083347 @default.
• W4365514687 cites W2105381170 @default.
• W4365514687 cites W2107284173 @default.
• W4365514687 cites W2110480216 @default.
• W4365514687 cites W2112422556 @default.
• W4365514687 cites W2116909658 @default.
• W4365514687 cites W2119940038 @default.
• W4365514687 cites W2122677163 @default.
• W4365514687 cites W2127787997 @default.
• W4365514687 cites W2129477690 @default.
• W4365514687 cites W2129852286 @default.
• W4365514687 cites W2145769191 @default.
• W4365514687 cites W2145901145 @default.
• W4365514687 cites W2150433066 @default.
• W4365514687 cites W2156098321 @default.
• W4365514687 cites W2158696439 @default.
• W4365514687 cites W2163900716 @default.
• W4365514687 cites W2169921558 @default.
• W4365514687 cites W2274433470 @default.
• W4365514687 cites W2305842675 @default.
• W4365514687 cites W2333829489 @default.
• W4365514687 cites W2404341997 @default.
• W4365514687 cites W2411374572 @default.
• W4365514687 cites W2468168745 @default.
• W4365514687 cites W2522745591 @default.
• W4365514687 cites W2581605534 @default.
• W4365514687 cites W2582602949 @default.
• W4365514687 cites W2621689399 @default.
• W4365514687 cites W2758526267 @default.
• W4365514687 cites W2766738149 @default.
• W4365514687 cites W2767766003 @default.
• W4365514687 cites W2900188589 @default.
• W4365514687 cites W2912367615 @default.
• W4365514687 cites W2972947847 @default.
• W4365514687 cites W2991792334 @default.
• W4365514687 cites W3004230628 @default.
• W4365514687 cites W3120963854 @default.
• W4365514687 cites W4220697225 @default.
• W4365514687 doi "https://doi.org/10.3389/fphar.2023.1099056" @default.
• W4365514687 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37124211" @default.
• W4365514687 hasPublicationYear "2023" @default.
• W4365514687 type Work @default.
• W4365514687 citedByCount "1" @default.
• W4365514687 countsByYear W43655146872023 @default.
• W4365514687 crossrefType "journal-article" @default.
• W4365514687 hasAuthorship W4365514687A5006822602 @default.
• W4365514687 hasAuthorship W4365514687A5024629778 @default.
• W4365514687 hasAuthorship W4365514687A5055650881 @default.
• W4365514687 hasAuthorship W4365514687A5066716873 @default.
• W4365514687 hasAuthorship W4365514687A5073335728 @default.
• W4365514687 hasAuthorship W4365514687A5090907351 @default.
• W4365514687 hasBestOaLocation W43655146871 @default.
• W4365514687 hasConcept C102652120 @default.
• W4365514687 hasConcept C126322002 @default.
• W4365514687 hasConcept C142724271 @default.
• W4365514687 hasConcept C168563851 @default.
• W4365514687 hasConcept C177713679 @default.
• W4365514687 hasConcept C198826908 @default.
• W4365514687 hasConcept C2779389132 @default.
• W4365514687 hasConcept C2911091166 @default.
• W4365514687 hasConcept C60644358 @default.
• W4365514687 hasConcept C71924100 @default.

• next