FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365518056> ?p ?o ?g. }

• W4365518056 endingPage "109329" @default.
• W4365518056 startingPage "109329" @default.
• W4365518056 abstract "Evaluation of type I interferons (IFNs) in inflammatory or autoimmune diseases is challenging because of their rapid clearance in peripheral blood. The IFN gene expression signature has recently been used to evaluate the IFN status; however, this is often a labor-intensive and time-consuming procedure. Therefore, we assessed the feasibility of measuring expression of an IFN-inducible protein, CD169 (Siglec-1), on monocytes and circulating levels of soluble CD169 as alternative markers for type I IFN status in various pediatric inflammatory diseases. Data from flow cytometric analysis of surface CD169 on monocytes and an enzyme-linked immunosorbent assay of soluble CD169 in peripheral blood were compared with serum IFN-α levels in 8 patients with viral infections, 5 with bacterial infections, 10 with systemic lupus erythematosus (SLE), 5 with Kikuchi-Fujimoto disease (KFD), 7 with Kawasaki disease (KD), and 8 with inflammatory bowel disease (IBD), and in 8 healthy controls. Surface CD169 expression was detected mainly on CD14+ monocytes and was significantly increased in patients with viral infections, SLE, and KFD, but not in patients with bacterial infections, KD, and IBD. There were similar trends for circulating soluble CD169; however, there was a significant increase only in patients with viral infections. Surface CD169 levels were significantly correlated with serum levels of IFN-α and soluble CD169. Analysis of CD169 expression on CD14+ monocytes may be useful for rapid assessment of type I IFN status for differentiation of pediatric inflammatory diseases from type 1 IFN-mediated diseases." @default.
• W4365518056 created "2023-04-15" @default.
• W4365518056 creator A5005227250 @default.
• W4365518056 creator A5011260736 @default.
• W4365518056 creator A5046978467 @default.
• W4365518056 creator A5050498612 @default.
• W4365518056 creator A5054998216 @default.
• W4365518056 creator A5056410623 @default.
• W4365518056 creator A5062024056 @default.
• W4365518056 creator A5067305872 @default.
• W4365518056 date "2023-05-01" @default.
• W4365518056 modified "2023-10-18" @default.
• W4365518056 title "CD169 expression on monocytes as a marker for assessing type I interferon status in pediatric inflammatory diseases" @default.
• W4365518056 cites W2006194219 @default.
• W4365518056 cites W2094596462 @default.
• W4365518056 cites W2133402546 @default.
• W4365518056 cites W2138282259 @default.
• W4365518056 cites W2148936706 @default.
• W4365518056 cites W2155139766 @default.
• W4365518056 cites W2160849060 @default.
• W4365518056 cites W2565022774 @default.
• W4365518056 cites W2567283285 @default.
• W4365518056 cites W2604027935 @default.
• W4365518056 cites W2606492431 @default.
• W4365518056 cites W2776031167 @default.
• W4365518056 cites W2790466592 @default.
• W4365518056 cites W2935762014 @default.
• W4365518056 cites W2951057964 @default.
• W4365518056 cites W2965565685 @default.
• W4365518056 cites W2967035454 @default.
• W4365518056 cites W2969830288 @default.
• W4365518056 cites W2980487636 @default.
• W4365518056 cites W3004951004 @default.
• W4365518056 cites W3032564210 @default.
• W4365518056 cites W3105363380 @default.
• W4365518056 cites W4200517016 @default.
• W4365518056 cites W4220653746 @default.
• W4365518056 doi "https://doi.org/10.1016/j.clim.2023.109329" @default.
• W4365518056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37061149" @default.
• W4365518056 hasPublicationYear "2023" @default.
• W4365518056 type Work @default.
• W4365518056 citedByCount "2" @default.
• W4365518056 countsByYear W43655180562023 @default.
• W4365518056 crossrefType "journal-article" @default.
• W4365518056 hasAuthorship W4365518056A5005227250 @default.
• W4365518056 hasAuthorship W4365518056A5011260736 @default.
• W4365518056 hasAuthorship W4365518056A5046978467 @default.
• W4365518056 hasAuthorship W4365518056A5050498612 @default.
• W4365518056 hasAuthorship W4365518056A5054998216 @default.
• W4365518056 hasAuthorship W4365518056A5056410623 @default.
• W4365518056 hasAuthorship W4365518056A5062024056 @default.
• W4365518056 hasAuthorship W4365518056A5067305872 @default.
• W4365518056 hasConcept C126322002 @default.
• W4365518056 hasConcept C203014093 @default.
• W4365518056 hasConcept C2776178377 @default.
• W4365518056 hasConcept C2776820930 @default.
• W4365518056 hasConcept C2778260677 @default.
• W4365518056 hasConcept C2778513237 @default.
• W4365518056 hasConcept C2779134260 @default.
• W4365518056 hasConcept C2781184567 @default.
• W4365518056 hasConcept C2781423770 @default.
• W4365518056 hasConcept C553184892 @default.
• W4365518056 hasConcept C71924100 @default.
• W4365518056 hasConceptScore W4365518056C126322002 @default.
• W4365518056 hasConceptScore W4365518056C203014093 @default.
• W4365518056 hasConceptScore W4365518056C2776178377 @default.
• W4365518056 hasConceptScore W4365518056C2776820930 @default.
• W4365518056 hasConceptScore W4365518056C2778260677 @default.
• W4365518056 hasConceptScore W4365518056C2778513237 @default.
• W4365518056 hasConceptScore W4365518056C2779134260 @default.
• W4365518056 hasConceptScore W4365518056C2781184567 @default.
• W4365518056 hasConceptScore W4365518056C2781423770 @default.
• W4365518056 hasConceptScore W4365518056C553184892 @default.
• W4365518056 hasConceptScore W4365518056C71924100 @default.
• W4365518056 hasFunder F4320325894 @default.
• W4365518056 hasLocation W43655180561 @default.
• W4365518056 hasLocation W43655180562 @default.
• W4365518056 hasOpenAccess W4365518056 @default.
• W4365518056 hasPrimaryLocation W43655180561 @default.
• W4365518056 hasRelatedWork W1584783298 @default.
• W4365518056 hasRelatedWork W1975953426 @default.
• W4365518056 hasRelatedWork W2004207884 @default.
• W4365518056 hasRelatedWork W2051994399 @default.
• W4365518056 hasRelatedWork W2093050394 @default.
• W4365518056 hasRelatedWork W2392850455 @default.
• W4365518056 hasRelatedWork W2623772047 @default.
• W4365518056 hasRelatedWork W2921562765 @default.
• W4365518056 hasRelatedWork W3031785506 @default.
• W4365518056 hasRelatedWork W4212978339 @default.
• W4365518056 hasVolume "250" @default.
• W4365518056 isParatext "false" @default.
• W4365518056 isRetracted "false" @default.
• W4365518056 workType "article" @default.