Matches in SemOpenAlex for { <https://semopenalex.org/work/W4365519838> ?p ?o ?g. }
- W4365519838 endingPage "18" @default.
- W4365519838 startingPage "1" @default.
- W4365519838 abstract "Sodium butyrate (NaB) can regulate lipid metabolism and inhibit hepatic steatosis. This study aimed to investigate whether NaB can alleviate fructose-induced hepatic steatosis via remodeling the gut microbiota and evaluate the anti-fatty liver mechanisms. The results showed that NaB and NaB-remodeled gut microbiota significantly alleviated fructose-induced hepatic steatosis and increased plasma uric acid and fructose levels. Furthermore, both NaB and NaB-remodeled gut microbiota increased the abundance of <i>Lactobacillus</i> and altered the levels of plasma amino acids [upregulating gamma-amino butyric acid (GABA) and downregulating L-glutamic acid and L-arginine] in fructose-exposed mice. The correlation analysis showed that GABA levels positively correlated with <i>Lactobacillus</i> abundance, and increased GABA levels might promote the reduction of the hepatic triglyceride content. Further studies confirmed that GABA significantly reduced lipid deposition in mouse hepatocytes induced via fructose pretreatment <i>in vitro</i>. These findings suggested that NaB could ameliorate fructose-induced hepatic steatosis by regulating gut microbiota." @default.
- W4365519838 created "2023-04-15" @default.
- W4365519838 creator A5004479020 @default.
- W4365519838 creator A5007506428 @default.
- W4365519838 creator A5031976409 @default.
- W4365519838 creator A5034709419 @default.
- W4365519838 creator A5036361101 @default.
- W4365519838 creator A5048025879 @default.
- W4365519838 creator A5064372942 @default.
- W4365519838 date "2023-03-01" @default.
- W4365519838 modified "2023-10-05" @default.
- W4365519838 title "Sodium butyrate ameliorates hepatic steatosis via modulating gut microbiota in fructose-exposed mice" @default.
- W4365519838 cites W1521042725 @default.
- W4365519838 cites W1965211757 @default.
- W4365519838 cites W1972799731 @default.
- W4365519838 cites W2011038073 @default.
- W4365519838 cites W2014632252 @default.
- W4365519838 cites W2023535481 @default.
- W4365519838 cites W2023774232 @default.
- W4365519838 cites W2086500586 @default.
- W4365519838 cites W2088716662 @default.
- W4365519838 cites W2089611985 @default.
- W4365519838 cites W2098278200 @default.
- W4365519838 cites W2107040151 @default.
- W4365519838 cites W2108535517 @default.
- W4365519838 cites W2110936821 @default.
- W4365519838 cites W2112681005 @default.
- W4365519838 cites W2128992702 @default.
- W4365519838 cites W2132780790 @default.
- W4365519838 cites W2132916165 @default.
- W4365519838 cites W2134823147 @default.
- W4365519838 cites W2136759951 @default.
- W4365519838 cites W2149515881 @default.
- W4365519838 cites W2166349512 @default.
- W4365519838 cites W2167585764 @default.
- W4365519838 cites W2173139831 @default.
- W4365519838 cites W2178380008 @default.
- W4365519838 cites W2207483414 @default.
- W4365519838 cites W2210580213 @default.
- W4365519838 cites W2335470021 @default.
- W4365519838 cites W2414547980 @default.
- W4365519838 cites W2571212804 @default.
- W4365519838 cites W2784278159 @default.
- W4365519838 cites W2787707131 @default.
- W4365519838 cites W2788821298 @default.
- W4365519838 cites W2898509099 @default.
- W4365519838 cites W2912465744 @default.
- W4365519838 cites W2936328687 @default.
- W4365519838 cites W2939052468 @default.
- W4365519838 cites W2952125490 @default.
- W4365519838 cites W3108977379 @default.
- W4365519838 cites W3118320443 @default.
- W4365519838 cites W3176559973 @default.
- W4365519838 cites W3215620458 @default.
- W4365519838 cites W4200279068 @default.
- W4365519838 cites W4285725468 @default.
- W4365519838 cites W4292994528 @default.
- W4365519838 cites W4293276412 @default.
- W4365519838 doi "https://doi.org/10.26599/fshw.2022.9250082" @default.
- W4365519838 hasPublicationYear "2023" @default.
- W4365519838 type Work @default.
- W4365519838 citedByCount "0" @default.
- W4365519838 crossrefType "journal-article" @default.
- W4365519838 hasAuthorship W4365519838A5004479020 @default.
- W4365519838 hasAuthorship W4365519838A5007506428 @default.
- W4365519838 hasAuthorship W4365519838A5031976409 @default.
- W4365519838 hasAuthorship W4365519838A5034709419 @default.
- W4365519838 hasAuthorship W4365519838A5036361101 @default.
- W4365519838 hasAuthorship W4365519838A5048025879 @default.
- W4365519838 hasAuthorship W4365519838A5064372942 @default.
- W4365519838 hasBestOaLocation W43655198381 @default.
- W4365519838 hasConcept C100544194 @default.
- W4365519838 hasConcept C104317684 @default.
- W4365519838 hasConcept C126322002 @default.
- W4365519838 hasConcept C134018914 @default.
- W4365519838 hasConcept C185592680 @default.
- W4365519838 hasConcept C2776175330 @default.
- W4365519838 hasConcept C2776970464 @default.
- W4365519838 hasConcept C2776979534 @default.
- W4365519838 hasConcept C2778163477 @default.
- W4365519838 hasConcept C2778772119 @default.
- W4365519838 hasConcept C2778913445 @default.
- W4365519838 hasConcept C2778942008 @default.
- W4365519838 hasConcept C2779134260 @default.
- W4365519838 hasConcept C539455810 @default.
- W4365519838 hasConcept C55493867 @default.
- W4365519838 hasConcept C71924100 @default.
- W4365519838 hasConcept C86803240 @default.
- W4365519838 hasConceptScore W4365519838C100544194 @default.
- W4365519838 hasConceptScore W4365519838C104317684 @default.
- W4365519838 hasConceptScore W4365519838C126322002 @default.
- W4365519838 hasConceptScore W4365519838C134018914 @default.
- W4365519838 hasConceptScore W4365519838C185592680 @default.
- W4365519838 hasConceptScore W4365519838C2776175330 @default.
- W4365519838 hasConceptScore W4365519838C2776970464 @default.
- W4365519838 hasConceptScore W4365519838C2776979534 @default.
- W4365519838 hasConceptScore W4365519838C2778163477 @default.
- W4365519838 hasConceptScore W4365519838C2778772119 @default.