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- W4365787241 abstract "The results of two studies, one in Finland and one in the U.S.A., raise the possibility that fetal damage previously attributed to phenytoin and other anticonvulsant drugs, principally phenobarbitone, may be due to epilepsy itself. In the U.S.A., drug-exposure information was collected before delivery in a cohort of 50 282 mother/child pairs. The total malformation-rate in 305 children born to epileptic mothers was 10·5%, as against 6·4% in the remainder (p<0·01); corresponding rates for major malformations were 6·6% and 2·7%. When the fathers had epilepsy, the malformation-rates in their children were intermediate." @default.
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- W4365787241 date "1976-02-01" @default.
- W4365787241 modified "2023-10-17" @default.
- W4365787241 title "ANTICONVULSANTS AND PARENTAL EPILEPSY IN THE DEVELOPMENT OF BIRTH DEFECTS" @default.
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- W4365787241 doi "https://doi.org/10.1016/s0140-6736(76)91403-3" @default.
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