FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366084940> ?p ?o ?g. }

• W4366084940 endingPage "57" @default.
• W4366084940 startingPage "48" @default.
• W4366084940 abstract "The incorporation of skin flaps in wound closure management with its cosmetic implications has appeared as a gleam of hope in providing desirable outcomes. Given the influence of extrinsic and intrinsic factors, skin flaps are prone to several complications, including ischemia-reperfusion injury (IRI). Numerous attempts have been undertaken to enhance the survival rate of skin flaps entailing pre/post-conditioning with surgical and pharmacological modalities. Various cellular and molecular mechanisms are employed in these approaches in order to reduce inflammation, promote angiogenesis and blood perfusion, and induce apoptosis and autophagy. With the emerging role of multiple stem cell lineages and their ability to improve skin flap viability, these approaches are increasingly being used to develop even more translationally applicable methods. Therefore, this review aims at providing current evidence around pharmacological interventions for improving skin flap survival and discussing their underlying mechanism of action. The incorporation of skin flaps in wound closure management with its cosmetic implications has appeared as a gleam of hope in providing desirable outcomes. Given the influence of extrinsic and intrinsic factors, skin flaps are prone to several complications, including ischemia-reperfusion injury (IRI). Numerous attempts have been undertaken to enhance the survival rate of skin flaps entailing pre/post-conditioning with surgical and pharmacological modalities. Various cellular and molecular mechanisms are employed in these approaches in order to reduce inflammation, promote angiogenesis and blood perfusion, and induce apoptosis and autophagy. With the emerging role of multiple stem cell lineages and their ability to improve skin flap viability, these approaches are increasingly being used to develop even more translationally applicable methods. Therefore, this review aims at providing current evidence around pharmacological interventions for improving skin flap survival and discussing their underlying mechanism of action." @default.
• W4366084940 created "2023-04-19" @default.
• W4366084940 creator A5029077125 @default.
• W4366084940 creator A5034729928 @default.
• W4366084940 creator A5038337955 @default.
• W4366084940 creator A5040278060 @default.
• W4366084940 creator A5043055423 @default.
• W4366084940 date "2023-07-01" @default.
• W4366084940 modified "2023-09-24" @default.
• W4366084940 title "The current state of knowledge on how to improve skin flap survival: A review" @default.
• W4366084940 cites W1569975913 @default.
• W4366084940 cites W1754330898 @default.
• W4366084940 cites W1824781773 @default.
• W4366084940 cites W1909750048 @default.
• W4366084940 cites W1964233929 @default.
• W4366084940 cites W1975851670 @default.
• W4366084940 cites W1990728465 @default.
• W4366084940 cites W1998423287 @default.
• W4366084940 cites W2004099545 @default.
• W4366084940 cites W2013055465 @default.
• W4366084940 cites W2017248146 @default.
• W4366084940 cites W2019075176 @default.
• W4366084940 cites W2019344114 @default.
• W4366084940 cites W2029565750 @default.
• W4366084940 cites W2048014052 @default.
• W4366084940 cites W2057655540 @default.
• W4366084940 cites W2061515370 @default.
• W4366084940 cites W2064181679 @default.
• W4366084940 cites W2064563691 @default.
• W4366084940 cites W2066379658 @default.
• W4366084940 cites W2067652468 @default.
• W4366084940 cites W2079821245 @default.
• W4366084940 cites W2088022459 @default.
• W4366084940 cites W2089728480 @default.
• W4366084940 cites W2091300920 @default.
• W4366084940 cites W2091612632 @default.
• W4366084940 cites W2092772658 @default.
• W4366084940 cites W2095132685 @default.
• W4366084940 cites W2108824149 @default.
• W4366084940 cites W2111492359 @default.
• W4366084940 cites W2140066742 @default.
• W4366084940 cites W2143720200 @default.
• W4366084940 cites W2160252183 @default.
• W4366084940 cites W2162314147 @default.
• W4366084940 cites W2168038663 @default.
• W4366084940 cites W2231573172 @default.
• W4366084940 cites W2294172785 @default.
• W4366084940 cites W2322619031 @default.
• W4366084940 cites W2340487543 @default.
• W4366084940 cites W2563249908 @default.
• W4366084940 cites W2588472934 @default.
• W4366084940 cites W2608013142 @default.
• W4366084940 cites W2626567585 @default.
• W4366084940 cites W2765774313 @default.
• W4366084940 cites W2810761008 @default.
• W4366084940 cites W2922233108 @default.
• W4366084940 cites W2936312634 @default.
• W4366084940 cites W2942534625 @default.
• W4366084940 cites W2964121209 @default.
• W4366084940 cites W2972963333 @default.
• W4366084940 cites W2980449100 @default.
• W4366084940 cites W2989035462 @default.
• W4366084940 cites W3000784050 @default.
• W4366084940 cites W3037578381 @default.
• W4366084940 cites W3044584906 @default.
• W4366084940 cites W3046528362 @default.
• W4366084940 cites W3083961837 @default.
• W4366084940 cites W3092891855 @default.
• W4366084940 cites W3096839365 @default.
• W4366084940 cites W3103243813 @default.
• W4366084940 cites W3120353917 @default.
• W4366084940 cites W3130091983 @default.
• W4366084940 cites W4200367613 @default.
• W4366084940 cites W4213436236 @default.
• W4366084940 cites W4246611578 @default.
• W4366084940 cites W4283368520 @default.
• W4366084940 cites W2044011790 @default.
• W4366084940 cites W2283505949 @default.
• W4366084940 doi "https://doi.org/10.1016/j.bjps.2023.04.021" @default.
• W4366084940 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37149909" @default.
• W4366084940 hasPublicationYear "2023" @default.
• W4366084940 type Work @default.
• W4366084940 citedByCount "0" @default.
• W4366084940 crossrefType "journal-article" @default.
• W4366084940 hasAuthorship W4366084940A5029077125 @default.
• W4366084940 hasAuthorship W4366084940A5034729928 @default.
• W4366084940 hasAuthorship W4366084940A5038337955 @default.
• W4366084940 hasAuthorship W4366084940A5040278060 @default.
• W4366084940 hasAuthorship W4366084940A5043055423 @default.
• W4366084940 hasConcept C111472728 @default.
• W4366084940 hasConcept C126322002 @default.
• W4366084940 hasConcept C138885662 @default.
• W4366084940 hasConcept C141071460 @default.
• W4366084940 hasConcept C144024400 @default.
• W4366084940 hasConcept C185592680 @default.
• W4366084940 hasConcept C190283241 @default.
• W4366084940 hasConcept C203014093 @default.
• W4366084940 hasConcept C203522944 @default.

• next