FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366124952> ?p ?o ?g. }

• W4366124952 endingPage "37" @default.
• W4366124952 startingPage "31" @default.
• W4366124952 abstract "In this study, we investigated the efficacy of Celtis choseniana Nakai (C. choseniana) as complementary herbal medicine to ameliorate androgenic alopecia (AGA). The effects of C. choseniana on AGA were evaluated using testosterone propionate-induced AGA mouse model and dihydrotestosterone-treated human hair follicle dermal papilla cells. In vivo, C. choseniana treatment deactivated androgen signaling by reducing the concentration of serum dihydrotestosterone level and expressions of 5α-reductase 2 and androgen receptor. Next, C. choseniana treatment increased the hair regrowth rate. Histological studies demonstrated that C. choseniana induced the anagen phase in testosterone propionate-induced AGA mouse model. Cellular proliferation was promoted by C. choseniana treatment via increasing the expression of proliferation factors, such as proliferating cell nuclear antigen and cyclin D1. Furthermore, C. choseniana treatment increased the expression of proteins related to the Wnt/β-catenin signaling pathway. In addition, dickkopf-1, a Wnt inhibitor, was downregulated with C. choseniana treatment. Likewise, C. choseniana treatment promoted cellular proliferation in vitro. This study demonstrated the inhibitory effect of C. choseniana on androgen-induced AGA. Moreover, C. choseniana induced activation of Wnt/β-catenin signaling, resulting in prolonged anagen and cellular proliferation. Therefore, we suggest that C. choseniana can be used as a therapeutic agent to alleviate AGA." @default.
• W4366124952 created "2023-04-19" @default.
• W4366124952 creator A5000487079 @default.
• W4366124952 creator A5022259368 @default.
• W4366124952 creator A5041912792 @default.
• W4366124952 creator A5058954645 @default.
• W4366124952 creator A5071485475 @default.
• W4366124952 creator A5074259331 @default.
• W4366124952 date "2023-03-31" @default.
• W4366124952 modified "2023-09-25" @default.
• W4366124952 title "Therapeutic Potentiality of Celtis choseniana Nakai on Androgenic Alopecia through Repression of Androgen Action and Modulation of Wnt/β-catenin Signaling" @default.
• W4366124952 cites W1969051501 @default.
• W4366124952 cites W1969540624 @default.
• W4366124952 cites W2007166173 @default.
• W4366124952 cites W2032129913 @default.
• W4366124952 cites W2093117337 @default.
• W4366124952 cites W2102313656 @default.
• W4366124952 cites W2136169401 @default.
• W4366124952 cites W2149470433 @default.
• W4366124952 cites W2169630576 @default.
• W4366124952 cites W2171969981 @default.
• W4366124952 cites W2504292268 @default.
• W4366124952 cites W2597986029 @default.
• W4366124952 cites W2611507438 @default.
• W4366124952 cites W2756946608 @default.
• W4366124952 cites W2790816372 @default.
• W4366124952 cites W2790834310 @default.
• W4366124952 cites W2981917690 @default.
• W4366124952 cites W2991149675 @default.
• W4366124952 cites W2999847951 @default.
• W4366124952 cites W3044989718 @default.
• W4366124952 cites W3129039058 @default.
• W4366124952 cites W4210834452 @default.
• W4366124952 cites W4288056803 @default.
• W4366124952 doi "https://doi.org/10.20307/nps.2023.29.1.31" @default.
• W4366124952 hasPublicationYear "2023" @default.
• W4366124952 type Work @default.
• W4366124952 citedByCount "0" @default.
• W4366124952 crossrefType "journal-article" @default.
• W4366124952 hasAuthorship W4366124952A5000487079 @default.
• W4366124952 hasAuthorship W4366124952A5022259368 @default.
• W4366124952 hasAuthorship W4366124952A5041912792 @default.
• W4366124952 hasAuthorship W4366124952A5058954645 @default.
• W4366124952 hasAuthorship W4366124952A5071485475 @default.
• W4366124952 hasAuthorship W4366124952A5074259331 @default.
• W4366124952 hasBestOaLocation W43661249521 @default.
• W4366124952 hasConcept C121608353 @default.
• W4366124952 hasConcept C126322002 @default.
• W4366124952 hasConcept C134018914 @default.
• W4366124952 hasConcept C137620995 @default.
• W4366124952 hasConcept C185592680 @default.
• W4366124952 hasConcept C190283241 @default.
• W4366124952 hasConcept C199835354 @default.
• W4366124952 hasConcept C2777605378 @default.
• W4366124952 hasConcept C2777911890 @default.
• W4366124952 hasConcept C2779279991 @default.
• W4366124952 hasConcept C2779881493 @default.
• W4366124952 hasConcept C2780192828 @default.
• W4366124952 hasConcept C2781115071 @default.
• W4366124952 hasConcept C29537977 @default.
• W4366124952 hasConcept C30145163 @default.
• W4366124952 hasConcept C34688535 @default.
• W4366124952 hasConcept C502942594 @default.
• W4366124952 hasConcept C55493867 @default.
• W4366124952 hasConcept C61367390 @default.
• W4366124952 hasConcept C62112901 @default.
• W4366124952 hasConcept C62478195 @default.
• W4366124952 hasConcept C71315377 @default.
• W4366124952 hasConcept C71924100 @default.
• W4366124952 hasConcept C86803240 @default.
• W4366124952 hasConcept C88498014 @default.
• W4366124952 hasConcept C95444343 @default.
• W4366124952 hasConcept C98274493 @default.
• W4366124952 hasConceptScore W4366124952C121608353 @default.
• W4366124952 hasConceptScore W4366124952C126322002 @default.
• W4366124952 hasConceptScore W4366124952C134018914 @default.
• W4366124952 hasConceptScore W4366124952C137620995 @default.
• W4366124952 hasConceptScore W4366124952C185592680 @default.
• W4366124952 hasConceptScore W4366124952C190283241 @default.
• W4366124952 hasConceptScore W4366124952C199835354 @default.
• W4366124952 hasConceptScore W4366124952C2777605378 @default.
• W4366124952 hasConceptScore W4366124952C2777911890 @default.
• W4366124952 hasConceptScore W4366124952C2779279991 @default.
• W4366124952 hasConceptScore W4366124952C2779881493 @default.
• W4366124952 hasConceptScore W4366124952C2780192828 @default.
• W4366124952 hasConceptScore W4366124952C2781115071 @default.
• W4366124952 hasConceptScore W4366124952C29537977 @default.
• W4366124952 hasConceptScore W4366124952C30145163 @default.
• W4366124952 hasConceptScore W4366124952C34688535 @default.
• W4366124952 hasConceptScore W4366124952C502942594 @default.
• W4366124952 hasConceptScore W4366124952C55493867 @default.
• W4366124952 hasConceptScore W4366124952C61367390 @default.
• W4366124952 hasConceptScore W4366124952C62112901 @default.
• W4366124952 hasConceptScore W4366124952C62478195 @default.
• W4366124952 hasConceptScore W4366124952C71315377 @default.
• W4366124952 hasConceptScore W4366124952C71924100 @default.
• W4366124952 hasConceptScore W4366124952C86803240 @default.
• W4366124952 hasConceptScore W4366124952C88498014 @default.

• next