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- W4366126321 abstract "Morchella esculenta polysaccharides exhibit numerous probiotic activities, but their regulatory effects on the gut microbiota are unclear. This study was conducted to explore whether M. esculenta polysaccharides can regulate dysbacteriosis caused by a high-fat diet and relieve obesity. We extracted a water-soluble polysaccharide from M. esculenta (MPF, purity: 96.19%, consisting of 55.97% glucose, 9.63% xylose, and 22% mannose) that reduces mouse fat accumulation, alleviates obesity, and relieves liver injury, after 90 days of high-fat diet intake. This polysaccharide reversed dysbiosis and regulated the abundance of gut microbiota caused by a high-fat diet (restoring the ratio of Firmicutes/Bacteroidetes and changing the abundances of Lactobacillus, Dubosiella, and Faecalibaculum), increasing short-chain fatty acids and decreasing gene expression in the liver (glucose 6-phosphatase, glucose transporter 1, peroxisome proliferator-activated receptor gamma (PPAR) receptor-1α, PPARα, PPARγ, and CCAAT enhancer binding protein α). We identified a regulatory relationship between polysaccharides, gut microbiota, and the liver as a potential mechanism by which polysaccharides can alleviate obesity." @default.
- W4366126321 created "2023-04-19" @default.
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- W4366126321 date "2023-01-01" @default.
- W4366126321 modified "2023-10-14" @default.
- W4366126321 title "Effect of water-soluble polysaccharides from <i>Morchella esculenta</i> on high-fat diet-induced obese mice: changes in gut microbiota and metabolic functions" @default.
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- W4366126321 cites W1968834637 @default.
- W4366126321 cites W1969384498 @default.
- W4366126321 cites W1985151726 @default.
- W4366126321 cites W1986142882 @default.
- W4366126321 cites W1992370990 @default.
- W4366126321 cites W1993399595 @default.
- W4366126321 cites W1997380192 @default.
- W4366126321 cites W2000920418 @default.
- W4366126321 cites W2006815039 @default.
- W4366126321 cites W2021220730 @default.
- W4366126321 cites W2021749223 @default.
- W4366126321 cites W2025207079 @default.
- W4366126321 cites W2040153748 @default.
- W4366126321 cites W2060185417 @default.
- W4366126321 cites W2063996623 @default.
- W4366126321 cites W2092537435 @default.
- W4366126321 cites W2095158284 @default.
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- W4366126321 doi "https://doi.org/10.1039/d3fo00574g" @default.
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