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- W4366165117 abstract "Nadamanee et al (Circulation March 24, 2023; doi:10.1161/CIRCULATIONAHA.122.063367, PMID 36960730) reported long-term outcomes of the BRAVO study (BRugada Ablation of Ventricular fibrillation substrate Ongoing multicenter registry), an international, multicenter, observational study of patients with Brugada syndrome (BrS) with recurrent ventricular fibrillation (VF) undergoing epicardial ablation. All patients in the registry had to have a spontaneous or provoked (by sodium channel blocker administration) type 1 Brugada pattern on the electrocardiogram (ECG), plus symptoms including history of cardiac arrest or arrhythmic syncope with later documentation of VF episodes. They all had to have undergone substrate ablation to prevent VF recurrences, including implantable cardioverter-defibrillator (ICD) shocks for VF. Substrate was identified using 3-dimensional mapping in the right ventricular (RV) and left ventricular (LV) endocardium and epicardium and was characterized as areas containing abnormal electrograms. Abnormal electrograms were defined as those having low voltage, split or fractionation, long duration, or late potentials. Programmed stimulation was performed for ventricular tachycardia (VT) and VF induction at the beginning of the procedure and after ablation completion. Ablation end points included targeting any ventricular premature depolarizations triggering VF if present and frequent enough to allow for mapping, plus elimination of the mid and late components of any abnormal electrograms. Patients were followed within 1 month of ablation and with in-person evaluation or remote monitoring every 3 months thereafter. The primary study end point was death or recurrent VF episodes." @default.
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- W4366165117 date "2023-06-01" @default.
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- W4366165117 title "EP News: Allied Professionals" @default.
- W4366165117 doi "https://doi.org/10.1016/j.hrthm.2023.04.008" @default.
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