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- W4366173652 abstract "Commensal bacteria have been associated with the development of cutaneous squamous cell carcinoma. A bacterial culture taken from a cutaneous squamous cell carcinoma lesion well identified the abundance of bacteria. However, the impact of these microorganisms on the prognosis of cutaneous squamous cell carcinoma is uncertain. Corynebacterium is widely distributed in nature in animal microbiota and is generally thought to be nonpathogenic, yet they can exploit impaired host defenses on occasion. However, the particular properties of the Corynebacterium remain mostly unclear. We examined that cutaneous squamous cell carcinoma cases treated in our institution were enrolled in this study, and the commensal bacterial profiles in these patients were investigated. A total of 80 patients with cutaneous squamous cell carcinoma which bacteria were detected from the bacterial culture were enrolled in this study. Among various detected bacteria from cutaneous squamous cell carcinoma, the log-rank test using the Kaplan-Meier technique identified that Corynebacterium-positive patients showed unfavorable survival. Univariate and multivariate analyses showed that Corynebacterium-positivity with cutaneous squamous cell carcinoma was an independent prognostic factor." @default.
- W4366173652 created "2023-04-19" @default.
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- W4366173652 date "2023-05-01" @default.
- W4366173652 modified "2023-09-28" @default.
- W4366173652 title "528 Corynebacterium species is an independent prognostic factor in cutaneous squamous cell carcinoma" @default.
- W4366173652 doi "https://doi.org/10.1016/j.jid.2023.03.534" @default.
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