Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366174791> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4366174791 abstract "Background: Pregnancy is characterized as a physiological period with greater sensitivity to insulin resistance and changes in oxidative stress. Purinergic signaling is directly related to diabetes, as this condition modifies the concentration of extracellular ATP and the level of degradation of ATP to adenosine. Objective: Analyze oxidative stress and the purinergic system in pregnant women with Gestational Diabetes Mellitus (GDM) and compare them with low-risk pregnant women (LR). Materials and methods: The research was of a quantitative approach of an experimental nature. The study was carried out at the Clínica da Mulher, which serves high-risk pregnant women, and at the Family Health Centers, which serves low-risk pregnant women, both located in Chapecó, Santa Catarina, Brazil. Results: From the analysis, it was observed that oxidative stress was increased in pregnant women in LR compared to pregnant women with GDM by increasing the concentration of TBARS and reducing the concentration of Carbonyl Protein in pregnant women with LR. Regarding the purinergic system, there was a significant decrease in the hydrolysis of the nucleotides ATP, ADP, and AMP in pregnant women with GDM, and a significant increase in the hydrolysis of ADA, also in pregnant women with GDM. Conclusion: Therefore, pregnant women with GDM have less oxidative stress compared to pregnant women in LR concerning TBARS and Carbonyl Protein markers, thus allowing a greater antioxidant defense mechanism. Furthermore, concerning the purinergic system, there is an increase in the activity of ADA, which is directly related to the immunosuppression process, a necessary condition for the protection of the fetus during the gestational period." @default.
- W4366174791 created "2023-04-19" @default.
- W4366174791 creator A5017976715 @default.
- W4366174791 creator A5026539748 @default.
- W4366174791 creator A5035828113 @default.
- W4366174791 creator A5074346904 @default.
- W4366174791 creator A5081240630 @default.
- W4366174791 creator A5083542709 @default.
- W4366174791 creator A5088648817 @default.
- W4366174791 creator A5006849415 @default.
- W4366174791 date "2023-04-14" @default.
- W4366174791 modified "2023-09-30" @default.
- W4366174791 title "Biochemical analysis of oxidative stress and purinergic system in pregnant women with gestational diabetes mellitus" @default.
- W4366174791 doi "https://doi.org/10.11606/issn.2176-7262.rmrp.2023.193812" @default.
- W4366174791 hasPublicationYear "2023" @default.
- W4366174791 type Work @default.
- W4366174791 citedByCount "0" @default.
- W4366174791 crossrefType "journal-article" @default.
- W4366174791 hasAuthorship W4366174791A5006849415 @default.
- W4366174791 hasAuthorship W4366174791A5017976715 @default.
- W4366174791 hasAuthorship W4366174791A5026539748 @default.
- W4366174791 hasAuthorship W4366174791A5035828113 @default.
- W4366174791 hasAuthorship W4366174791A5074346904 @default.
- W4366174791 hasAuthorship W4366174791A5081240630 @default.
- W4366174791 hasAuthorship W4366174791A5083542709 @default.
- W4366174791 hasAuthorship W4366174791A5088648817 @default.
- W4366174791 hasBestOaLocation W43661747911 @default.
- W4366174791 hasConcept C126322002 @default.
- W4366174791 hasConcept C134018914 @default.
- W4366174791 hasConcept C2776151105 @default.
- W4366174791 hasConcept C2776991684 @default.
- W4366174791 hasConcept C2777352226 @default.
- W4366174791 hasConcept C2779234561 @default.
- W4366174791 hasConcept C2779434492 @default.
- W4366174791 hasConcept C2780829032 @default.
- W4366174791 hasConcept C46973012 @default.
- W4366174791 hasConcept C54355233 @default.
- W4366174791 hasConcept C555293320 @default.
- W4366174791 hasConcept C57306754 @default.
- W4366174791 hasConcept C71924100 @default.
- W4366174791 hasConcept C86803240 @default.
- W4366174791 hasConceptScore W4366174791C126322002 @default.
- W4366174791 hasConceptScore W4366174791C134018914 @default.
- W4366174791 hasConceptScore W4366174791C2776151105 @default.
- W4366174791 hasConceptScore W4366174791C2776991684 @default.
- W4366174791 hasConceptScore W4366174791C2777352226 @default.
- W4366174791 hasConceptScore W4366174791C2779234561 @default.
- W4366174791 hasConceptScore W4366174791C2779434492 @default.
- W4366174791 hasConceptScore W4366174791C2780829032 @default.
- W4366174791 hasConceptScore W4366174791C46973012 @default.
- W4366174791 hasConceptScore W4366174791C54355233 @default.
- W4366174791 hasConceptScore W4366174791C555293320 @default.
- W4366174791 hasConceptScore W4366174791C57306754 @default.
- W4366174791 hasConceptScore W4366174791C71924100 @default.
- W4366174791 hasConceptScore W4366174791C86803240 @default.
- W4366174791 hasIssue "1" @default.
- W4366174791 hasLocation W43661747911 @default.
- W4366174791 hasOpenAccess W4366174791 @default.
- W4366174791 hasPrimaryLocation W43661747911 @default.
- W4366174791 hasRelatedWork W1993795923 @default.
- W4366174791 hasRelatedWork W2039466440 @default.
- W4366174791 hasRelatedWork W2078493089 @default.
- W4366174791 hasRelatedWork W2095329316 @default.
- W4366174791 hasRelatedWork W2127396703 @default.
- W4366174791 hasRelatedWork W2140946182 @default.
- W4366174791 hasRelatedWork W2392247633 @default.
- W4366174791 hasRelatedWork W2397705441 @default.
- W4366174791 hasRelatedWork W2769473422 @default.
- W4366174791 hasRelatedWork W3031513826 @default.
- W4366174791 hasVolume "56" @default.
- W4366174791 isParatext "false" @default.
- W4366174791 isRetracted "false" @default.
- W4366174791 workType "article" @default.