Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366204522> ?p ?o ?g. }
- W4366204522 abstract "Abstract Oral leukoplakia (OLK) has received much attention due to its potential risk of malignant transformation. Studies have shown that when drug therapy is combined with photothermal therapy (PTT), not only can the cytotoxicity of the drug be enhanced, but also the heat energy can be used to kill the lesion cells, so we can combine drug therapy with PTT to enhance the therapeutic effect on OLK. However, with certain drawbacks due to its lack of targeting, fibroblast activating protein (FAP) has become an attractive target for OLK combination therapy. In this study, we used NGO-PEG loaded with FAP-targeting peptide and celecoxib (CXB) to construct a nano-drug delivery system CGPF for targeting OLK with high FAP expression, and confirmed the biocompatibility and therapeutic efficacy of CGPF by in vitro and in vivo experiments. Overall, the novel nano-drug delivery system CGPF proposed in this study showed a very significant potential for the combination therapy of OLK." @default.
- W4366204522 created "2023-04-19" @default.
- W4366204522 creator A5003360183 @default.
- W4366204522 creator A5007939470 @default.
- W4366204522 creator A5009247485 @default.
- W4366204522 creator A5010409955 @default.
- W4366204522 creator A5012722065 @default.
- W4366204522 creator A5036528361 @default.
- W4366204522 creator A5039062226 @default.
- W4366204522 creator A5062788756 @default.
- W4366204522 creator A5078683622 @default.
- W4366204522 date "2023-04-17" @default.
- W4366204522 modified "2023-10-16" @default.
- W4366204522 title "Nanodrug delivery system targeting FAP for the combined treatment of oral leukoplakia" @default.
- W4366204522 cites W1899923979 @default.
- W4366204522 cites W1964818072 @default.
- W4366204522 cites W1975515530 @default.
- W4366204522 cites W1991433828 @default.
- W4366204522 cites W2021550137 @default.
- W4366204522 cites W2028726843 @default.
- W4366204522 cites W2088693256 @default.
- W4366204522 cites W2145392140 @default.
- W4366204522 cites W2170211456 @default.
- W4366204522 cites W2202349529 @default.
- W4366204522 cites W2396342174 @default.
- W4366204522 cites W2776075526 @default.
- W4366204522 cites W2792780338 @default.
- W4366204522 cites W2884648948 @default.
- W4366204522 cites W2897397729 @default.
- W4366204522 cites W2906350257 @default.
- W4366204522 cites W2914493074 @default.
- W4366204522 cites W2922671339 @default.
- W4366204522 cites W2937769322 @default.
- W4366204522 cites W2947349177 @default.
- W4366204522 cites W2948955303 @default.
- W4366204522 cites W2949336848 @default.
- W4366204522 cites W2950080684 @default.
- W4366204522 cites W2972582180 @default.
- W4366204522 cites W2974740020 @default.
- W4366204522 cites W2986084405 @default.
- W4366204522 cites W3005458421 @default.
- W4366204522 cites W3007887106 @default.
- W4366204522 cites W3015736345 @default.
- W4366204522 cites W3038979222 @default.
- W4366204522 cites W3041254907 @default.
- W4366204522 cites W3100837006 @default.
- W4366204522 cites W3124893903 @default.
- W4366204522 cites W3128691973 @default.
- W4366204522 cites W3133659109 @default.
- W4366204522 cites W3149254341 @default.
- W4366204522 cites W3162445566 @default.
- W4366204522 cites W3165241559 @default.
- W4366204522 cites W3185036416 @default.
- W4366204522 cites W3185051492 @default.
- W4366204522 cites W4205225798 @default.
- W4366204522 cites W4214837337 @default.
- W4366204522 cites W4220924779 @default.
- W4366204522 cites W4285269007 @default.
- W4366204522 cites W4311456067 @default.
- W4366204522 doi "https://doi.org/10.21203/rs.3.rs-2776517/v1" @default.
- W4366204522 hasPublicationYear "2023" @default.
- W4366204522 type Work @default.
- W4366204522 citedByCount "0" @default.
- W4366204522 crossrefType "posted-content" @default.
- W4366204522 hasAuthorship W4366204522A5003360183 @default.
- W4366204522 hasAuthorship W4366204522A5007939470 @default.
- W4366204522 hasAuthorship W4366204522A5009247485 @default.
- W4366204522 hasAuthorship W4366204522A5010409955 @default.
- W4366204522 hasAuthorship W4366204522A5012722065 @default.
- W4366204522 hasAuthorship W4366204522A5036528361 @default.
- W4366204522 hasAuthorship W4366204522A5039062226 @default.
- W4366204522 hasAuthorship W4366204522A5062788756 @default.
- W4366204522 hasAuthorship W4366204522A5078683622 @default.
- W4366204522 hasBestOaLocation W43662045221 @default.
- W4366204522 hasConcept C126511603 @default.
- W4366204522 hasConcept C150903083 @default.
- W4366204522 hasConcept C178790620 @default.
- W4366204522 hasConcept C185592680 @default.
- W4366204522 hasConcept C207001950 @default.
- W4366204522 hasConcept C2776999253 @default.
- W4366204522 hasConcept C2779820397 @default.
- W4366204522 hasConcept C2780035454 @default.
- W4366204522 hasConcept C502942594 @default.
- W4366204522 hasConcept C71924100 @default.
- W4366204522 hasConcept C86803240 @default.
- W4366204522 hasConcept C98274493 @default.
- W4366204522 hasConceptScore W4366204522C126511603 @default.
- W4366204522 hasConceptScore W4366204522C150903083 @default.
- W4366204522 hasConceptScore W4366204522C178790620 @default.
- W4366204522 hasConceptScore W4366204522C185592680 @default.
- W4366204522 hasConceptScore W4366204522C207001950 @default.
- W4366204522 hasConceptScore W4366204522C2776999253 @default.
- W4366204522 hasConceptScore W4366204522C2779820397 @default.
- W4366204522 hasConceptScore W4366204522C2780035454 @default.
- W4366204522 hasConceptScore W4366204522C502942594 @default.
- W4366204522 hasConceptScore W4366204522C71924100 @default.
- W4366204522 hasConceptScore W4366204522C86803240 @default.
- W4366204522 hasConceptScore W4366204522C98274493 @default.
- W4366204522 hasLocation W43662045221 @default.
- W4366204522 hasOpenAccess W4366204522 @default.