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- W4366207695 abstract "Patients with metastatic pancreatic cancer have limited treatment options and a dismal prognosis. While RET fusion is rare (0.6%) in pancreatic cancer, the efficacy of RET-targeted treatment in patients with TRIM33-RET fusion has not been previously reported. Herein, we presented a case of a 68-year-old man with pancreatic cancer harboring TRIM33-RET fusion who responded remarkably to pralsetinib despite being intolerant to chemotherapy. To our knowledge, this is the first report on the clinical value of a single TRIM33-RET fusion in pancreatic cancer, which may benefit from the targeted therapy." @default.
- W4366207695 created "2023-04-19" @default.
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- W4366207695 date "2023-04-17" @default.
- W4366207695 modified "2023-10-06" @default.
- W4366207695 title "RET rearrangement-positive pancreatic cancer has remarkable response to pralsetinib: a case report" @default.
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- W4366207695 doi "https://doi.org/10.3389/fonc.2023.1078076" @default.
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