FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366228166> ?p ?o ?g. }

• W4366228166 endingPage "103" @default.
• W4366228166 startingPage "93" @default.
• W4366228166 abstract "Natural antisense transcripts (NATs) are endogenous RNAs opposite to sense transcripts, and they can significantly contribute to regulating various biological processes through multiple epigenetic mechanisms. NATs can affect their sense transcripts to regulate the growth and development of skeletal muscle. Our analysis of third-generation full-length transcriptome sequencing data revealed that NATs represented a significant portion of the lncRNA, accounting for up to 30.19%-33.35%. The expression of NATs correlated with myoblast differentiation, and genes expressing NATs were mainly involved in RNA synthesis, protein transport, and cell cycle. We found a NAT of MYOG (MYOG-NAT) in the data. We found that the MYOG-NAT could promote the differentiation of myoblasts in vitro. Additionally, knockdown of MYOG-NAT in vivo led to muscle fiber atrophy and muscle regeneration retardation. Molecular biology experiments demonstrated that MYOG-NAT enhances the stability of MYOG mRNA by competing with miR-128-2-5p, miR-19a-5p, and miR-19b-5p for binding to MYOG mRNA 3'UTR. These findings suggest that MYOG-NAT plays a critical role in skeletal muscle development and provides insights into the post-transcriptional regulation of NATs." @default.
• W4366228166 created "2023-04-19" @default.
• W4366228166 creator A5034376735 @default.
• W4366228166 creator A5051303656 @default.
• W4366228166 creator A5080748081 @default.
• W4366228166 creator A5082915637 @default.
• W4366228166 creator A5084451165 @default.
• W4366228166 creator A5084524545 @default.
• W4366228166 date "2023-06-01" @default.
• W4366228166 modified "2023-09-30" @default.
• W4366228166 title "Natural antisense transcript of MYOG regulates development and regeneration in skeletal muscle by shielding the binding sites of MicroRNAs of MYOG mRNA 3′UTR" @default.
• W4366228166 cites W1686333409 @default.
• W4366228166 cites W1913987579 @default.
• W4366228166 cites W1949326509 @default.
• W4366228166 cites W1964733862 @default.
• W4366228166 cites W1986130046 @default.
• W4366228166 cites W2003553455 @default.
• W4366228166 cites W2005506831 @default.
• W4366228166 cites W2009100350 @default.
• W4366228166 cites W2020556597 @default.
• W4366228166 cites W2023423982 @default.
• W4366228166 cites W2026222098 @default.
• W4366228166 cites W2041126213 @default.
• W4366228166 cites W2048120844 @default.
• W4366228166 cites W2059968749 @default.
• W4366228166 cites W2060424507 @default.
• W4366228166 cites W2085856891 @default.
• W4366228166 cites W2094057862 @default.
• W4366228166 cites W2100692492 @default.
• W4366228166 cites W2133968430 @default.
• W4366228166 cites W2174791834 @default.
• W4366228166 cites W2176415571 @default.
• W4366228166 cites W2255008317 @default.
• W4366228166 cites W2300506866 @default.
• W4366228166 cites W2301925216 @default.
• W4366228166 cites W2333782844 @default.
• W4366228166 cites W2782521778 @default.
• W4366228166 cites W2800608949 @default.
• W4366228166 cites W2883070801 @default.
• W4366228166 cites W2896519010 @default.
• W4366228166 cites W2950081451 @default.
• W4366228166 cites W2952666313 @default.
• W4366228166 cites W3138666682 @default.
• W4366228166 cites W4210596913 @default.
• W4366228166 cites W4297311845 @default.
• W4366228166 doi "https://doi.org/10.1016/j.bbrc.2023.04.050" @default.
• W4366228166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37104884" @default.
• W4366228166 hasPublicationYear "2023" @default.
• W4366228166 type Work @default.
• W4366228166 citedByCount "1" @default.
• W4366228166 countsByYear W43662281662023 @default.
• W4366228166 crossrefType "journal-article" @default.
• W4366228166 hasAuthorship W4366228166A5034376735 @default.
• W4366228166 hasAuthorship W4366228166A5051303656 @default.
• W4366228166 hasAuthorship W4366228166A5080748081 @default.
• W4366228166 hasAuthorship W4366228166A5082915637 @default.
• W4366228166 hasAuthorship W4366228166A5084451165 @default.
• W4366228166 hasAuthorship W4366228166A5084524545 @default.
• W4366228166 hasConcept C104317684 @default.
• W4366228166 hasConcept C105580179 @default.
• W4366228166 hasConcept C134018914 @default.
• W4366228166 hasConcept C145059251 @default.
• W4366228166 hasConcept C153911025 @default.
• W4366228166 hasConcept C173396325 @default.
• W4366228166 hasConcept C182516595 @default.
• W4366228166 hasConcept C202416437 @default.
• W4366228166 hasConcept C207200792 @default.
• W4366228166 hasConcept C22667442 @default.
• W4366228166 hasConcept C2779959927 @default.
• W4366228166 hasConcept C31258907 @default.
• W4366228166 hasConcept C41008148 @default.
• W4366228166 hasConcept C54355233 @default.
• W4366228166 hasConcept C86803240 @default.
• W4366228166 hasConcept C89604277 @default.
• W4366228166 hasConcept C95444343 @default.
• W4366228166 hasConceptScore W4366228166C104317684 @default.
• W4366228166 hasConceptScore W4366228166C105580179 @default.
• W4366228166 hasConceptScore W4366228166C134018914 @default.
• W4366228166 hasConceptScore W4366228166C145059251 @default.
• W4366228166 hasConceptScore W4366228166C153911025 @default.
• W4366228166 hasConceptScore W4366228166C173396325 @default.
• W4366228166 hasConceptScore W4366228166C182516595 @default.
• W4366228166 hasConceptScore W4366228166C202416437 @default.
• W4366228166 hasConceptScore W4366228166C207200792 @default.
• W4366228166 hasConceptScore W4366228166C22667442 @default.
• W4366228166 hasConceptScore W4366228166C2779959927 @default.
• W4366228166 hasConceptScore W4366228166C31258907 @default.
• W4366228166 hasConceptScore W4366228166C41008148 @default.
• W4366228166 hasConceptScore W4366228166C54355233 @default.
• W4366228166 hasConceptScore W4366228166C86803240 @default.
• W4366228166 hasConceptScore W4366228166C89604277 @default.
• W4366228166 hasConceptScore W4366228166C95444343 @default.
• W4366228166 hasLocation W43662281661 @default.
• W4366228166 hasLocation W43662281662 @default.
• W4366228166 hasOpenAccess W4366228166 @default.
• W4366228166 hasPrimaryLocation W43662281661 @default.
• W4366228166 hasRelatedWork W1564628503 @default.
• W4366228166 hasRelatedWork W1951464003 @default.

• next