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- W4366242891 abstract "Fortifying our preparedness to cope with biological threats by identifying and targeting virulence factors may be a preventative strategy for curtailing infectious disease outbreak. Virulence factors evoke successful pathogenic invasion, and the science and technology of genomics offers a way of identifying them, their agents and evolutionary ancestor. Genomics offers the possibility of deciphering if the release of a pathogen was intentional or natural by observing sequence and annotated data of the causative agent, and evidence of genetic engineering such as cloned vectors at restriction sites. However, to leverage and maximise the application of genomics to strengthen global interception system for real-time biothreat diagnostics, a complete genomic library of pathogenic and non-pathogenic agents will create a robust reference assembly that can be used to screen, characterise, track and trace new and existing strains. Encouraging ethical research sequencing pathogens found in animals and the environment, as well as creating a global space for collaboration will lead to effective global regulation and biosurveillance." @default.
- W4366242891 created "2023-04-20" @default.
- W4366242891 creator A5041332036 @default.
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- W4366242891 date "2022-01-12" @default.
- W4366242891 modified "2023-09-27" @default.
- W4366242891 title "Applied genomics for identification of virulent biothreats and for disease outbreak surveillance." @default.
- W4366242891 doi "https://doi.org/10.1136/postmj/postgradmedj-2021-139916" @default.
- W4366242891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37068737" @default.
- W4366242891 hasPublicationYear "2022" @default.
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