Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366248416> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W4366248416 endingPage "673" @default.
- W4366248416 startingPage "665" @default.
- W4366248416 abstract "Abstract Background Delta-8 tetrahydrocannabinol (Δ8-THC) is a naturally occurring or synthetically prepared cannabinoid that elicits psychological and physiological experiences commonly reported for its more infamous isomer, delta-9 tetrahydrocannabinol (Δ9-THC). Unlike Δ9-THC, Δ8-THC products are generally legal under federal law and there has been a rise in their usage. One of the main targets for detection and quantitation of Δ9-THC is its inactive metabolite, 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (Δ9-THC-COOH). Methods This study evaluated the ability of the currently used Δ9-THC-COOH immunoassay and gas chromatography–mass spectrometry (GC-MS) methods to detect 11-nor-9-carboxy-Δ8-tetrahydrocannabinol (Δ8-THC-COOH) and distinguish it from Δ9-THC-COOH. Results The EMIT II Plus® Cannabinoid immunoassay for Δ9-THC-COOH with a cutoff of 20 ng/mL showed positive results for Δ8-THC-COOH with concentrations of 30 ng/mL or higher. Although many of the ion fragments generated by mass spectrometry were found to overlap between the 2 compounds, the GC-MS method presently used to quantify Δ9-THC-COOH separated the 2 compounds sufficiently to identify them independently by relative retention time. Conclusion Current immunoassays and GC-MS methods should be evaluated for the ability to detect and distinguish the presence of Δ8-THC-COOH." @default.
- W4366248416 created "2023-04-20" @default.
- W4366248416 creator A5008171431 @default.
- W4366248416 creator A5032657548 @default.
- W4366248416 creator A5068483131 @default.
- W4366248416 date "2023-04-18" @default.
- W4366248416 modified "2023-09-29" @default.
- W4366248416 title "Evaluation of a Delta-9-Tetrahydrocannabinol Carboxylic Acid (Δ9-THC-COOH) Immunoassay and a Gas Chromatography–Mass Spectrometry (GC-MS) Method for the Detection of Delta-8-Tetrahydrocannabinol Carboxylic Acid (Δ8-THC-COOH)" @default.
- W4366248416 cites W2024599052 @default.
- W4366248416 cites W2949378941 @default.
- W4366248416 cites W3178636608 @default.
- W4366248416 cites W3197285055 @default.
- W4366248416 cites W3204341802 @default.
- W4366248416 cites W3210739779 @default.
- W4366248416 cites W3214094092 @default.
- W4366248416 cites W4200571375 @default.
- W4366248416 cites W4221084746 @default.
- W4366248416 cites W4229004415 @default.
- W4366248416 cites W4294433585 @default.
- W4366248416 cites W4306399083 @default.
- W4366248416 cites W4309680942 @default.
- W4366248416 doi "https://doi.org/10.1093/jalm/jfad017" @default.
- W4366248416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37071885" @default.
- W4366248416 hasPublicationYear "2023" @default.
- W4366248416 type Work @default.
- W4366248416 citedByCount "0" @default.
- W4366248416 crossrefType "journal-article" @default.
- W4366248416 hasAuthorship W4366248416A5008171431 @default.
- W4366248416 hasAuthorship W4366248416A5032657548 @default.
- W4366248416 hasAuthorship W4366248416A5068483131 @default.
- W4366248416 hasConcept C123460561 @default.
- W4366248416 hasConcept C159654299 @default.
- W4366248416 hasConcept C162356407 @default.
- W4366248416 hasConcept C170493617 @default.
- W4366248416 hasConcept C185592680 @default.
- W4366248416 hasConcept C203014093 @default.
- W4366248416 hasConcept C205345274 @default.
- W4366248416 hasConcept C2777477808 @default.
- W4366248416 hasConcept C2777846614 @default.
- W4366248416 hasConcept C2778563155 @default.
- W4366248416 hasConcept C2780420688 @default.
- W4366248416 hasConcept C2780871563 @default.
- W4366248416 hasConcept C2908858883 @default.
- W4366248416 hasConcept C2909046181 @default.
- W4366248416 hasConcept C2909767651 @default.
- W4366248416 hasConcept C43617362 @default.
- W4366248416 hasConcept C55493867 @default.
- W4366248416 hasConcept C86803240 @default.
- W4366248416 hasConceptScore W4366248416C123460561 @default.
- W4366248416 hasConceptScore W4366248416C159654299 @default.
- W4366248416 hasConceptScore W4366248416C162356407 @default.
- W4366248416 hasConceptScore W4366248416C170493617 @default.
- W4366248416 hasConceptScore W4366248416C185592680 @default.
- W4366248416 hasConceptScore W4366248416C203014093 @default.
- W4366248416 hasConceptScore W4366248416C205345274 @default.
- W4366248416 hasConceptScore W4366248416C2777477808 @default.
- W4366248416 hasConceptScore W4366248416C2777846614 @default.
- W4366248416 hasConceptScore W4366248416C2778563155 @default.
- W4366248416 hasConceptScore W4366248416C2780420688 @default.
- W4366248416 hasConceptScore W4366248416C2780871563 @default.
- W4366248416 hasConceptScore W4366248416C2908858883 @default.
- W4366248416 hasConceptScore W4366248416C2909046181 @default.
- W4366248416 hasConceptScore W4366248416C2909767651 @default.
- W4366248416 hasConceptScore W4366248416C43617362 @default.
- W4366248416 hasConceptScore W4366248416C55493867 @default.
- W4366248416 hasConceptScore W4366248416C86803240 @default.
- W4366248416 hasIssue "4" @default.
- W4366248416 hasLocation W43662484161 @default.
- W4366248416 hasLocation W43662484162 @default.
- W4366248416 hasOpenAccess W4366248416 @default.
- W4366248416 hasPrimaryLocation W43662484161 @default.
- W4366248416 hasRelatedWork W1989096515 @default.
- W4366248416 hasRelatedWork W2146019963 @default.
- W4366248416 hasRelatedWork W2153402428 @default.
- W4366248416 hasRelatedWork W2346110970 @default.
- W4366248416 hasRelatedWork W2496219227 @default.
- W4366248416 hasRelatedWork W2510812768 @default.
- W4366248416 hasRelatedWork W2573471063 @default.
- W4366248416 hasRelatedWork W2807609262 @default.
- W4366248416 hasRelatedWork W4229004415 @default.
- W4366248416 hasRelatedWork W4366248416 @default.
- W4366248416 hasVolume "8" @default.
- W4366248416 isParatext "false" @default.
- W4366248416 isRetracted "false" @default.
- W4366248416 workType "article" @default.