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- W4366265296 abstract "Long term monocular deprivation is considered to be necessary for the induction of significant ocular dominance plasticity in the adult visual cortex. In this study, we subjected adult mice to monocular deprivation for various durations and screened for changes in ocular dominance using dual-wavelength intrinsic signal optical imaging. We found that short-term deprivation was sufficient to cause a shift in ocular dominance and that these early-stage changes were detected only by near-infrared illumination. In addition, single-unit recordings showed that these early-stage changes primarily occurred in deep cortical layers. This early-stage ocular dominance shift was abolished by the blockade of NMDA receptors. In summary, our findings reveal an early phase of adult ocular dominance plasticity and provide the dynamics of adult plasticity." @default.
- W4366265296 created "2023-04-20" @default.
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- W4366265296 date "2023-07-01" @default.
- W4366265296 modified "2023-09-30" @default.
- W4366265296 title "The early stage of adult ocular dominance plasticity revealed by near-infrared optical imaging of intrinsic signals" @default.
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- W4366265296 doi "https://doi.org/10.1016/j.neuroimage.2023.120122" @default.
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