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• W4366290462 startingPage "3542" @default.
• W4366290462 abstract "Applications of submicron-scale particles are of rising interest in separation science due to their favorable surface-to-volume ratio and their fabrication of highly ordered structures. The uniformly dense packing beds in columns assembled from nanoparticles combined with an electroosmotic flow-driven system has great potential in a highly efficient separation system. Here, we packed capillary columns using a gravity method with synthesized nanoscale C18-SiO2 particles having diameters of 300–900 nm. The separation of small molecules and proteins was evaluated in the packed columns on a pressurized capillary electrochromatography platform. The run-to-run reproducibility regarding retention time and peak area for the PAHs using a column packed with 300 nm C18-SiO2 particles were less than 1.61% and 3.17%, respectively. Our study exhibited a systematic separation analysis of small molecules and proteins based on the columns packed with submicron particles combined with the pressurized capillary electrochromatography (pCEC) platform. This study may provide a promising analytical approach with extraordinary column efficiency, resolution, and speed for the separation of complex samples." @default.
• W4366290462 created "2023-04-20" @default.
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• W4366290462 date "2023-04-17" @default.
• W4366290462 modified "2023-10-16" @default.
• W4366290462 title "Submicron Nonporous Silica Particles for Enhanced Separation Performance in pCEC" @default.
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• W4366290462 doi "https://doi.org/10.3390/molecules28083542" @default.
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• W4366290462 hasPublicationYear "2023" @default.
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