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- W4366290844 abstract "We describe two cases of XDR Pseudomonas aeruginosa infection caused by a strain of public health concern recently associated with a nationwide outbreak of contaminated artificial tears. Both cases were detected through database review of genomes in the Enhanced Detection System for Hospital-Associated Transmission (EDS-HAT), a routine genome sequencing-based surveillance program. We generated a high-quality reference genome for the outbreak strain from one of the case isolates from our center and examined the mobile elements encoding blaVIM-80 and blaGES-9 carbapenemases. We then used publicly available P. aeruginosa genomes to explore the genetic relatedness and antimicrobial resistance genes of the outbreak strain." @default.
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- W4366290844 date "2023-04-17" @default.
- W4366290844 modified "2023-10-02" @default.
- W4366290844 title "Two artificial tears outbreak-associated cases of XDR<i>Pseudomonas aeruginosa</i>detected through whole genome sequencing-based surveillance" @default.
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- W4366290844 doi "https://doi.org/10.1101/2023.04.11.23288417" @default.
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