Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366293321> ?p ?o ?g. }
- W4366293321 abstract "Abiotic stresses, including drought, salinity, cold, heat, and heavy metals, extensively reducing global agricultural production. Traditional breeding approaches and transgenic technology have been widely used to mitigate the risks of these environmental stresses. The discovery of engineered nucleases as genetic scissors to carry out precise manipulation in crop stress-responsive genes and associated molecular network has paved the way for sustainable management of abiotic stress conditions. In this context, the clustered regularly interspaced short palindromic repeat-Cas (CRISPR/Cas)-based gene-editing tool has revolutionized due to its simplicity, accessibility, adaptability, flexibility, and wide applicability. This system has great potential to build up crop varieties with enhanced tolerance against abiotic stresses. In this review, we summarize the latest findings on understanding the mechanism of abiotic stress response in plants and the application of CRISPR/Cas-mediated gene-editing system towards enhanced tolerance to a multitude of stresses including drought, salinity, cold, heat, and heavy metals. We provide mechanistic insights on the CRISPR/Cas9-based genome editing technology. We also discuss applications of evolving genome editing techniques such as prime editing and base editing, mutant library production, transgene free and multiplexing to rapidly deliver modern crop cultivars adapted to abiotic stress conditions." @default.
- W4366293321 created "2023-04-20" @default.
- W4366293321 creator A5009709215 @default.
- W4366293321 creator A5022604004 @default.
- W4366293321 creator A5025570562 @default.
- W4366293321 creator A5048424631 @default.
- W4366293321 creator A5065891282 @default.
- W4366293321 creator A5066513950 @default.
- W4366293321 creator A5091297252 @default.
- W4366293321 date "2023-04-18" @default.
- W4366293321 modified "2023-09-30" @default.
- W4366293321 title "Application of CRISPR/Cas9-mediated gene editing for abiotic stress management in crop plants" @default.
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