Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366333698> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4366333698 abstract "Abstract Studies show oral Tadalafil and Diazepam suppositories each independently improve chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), leading providers to use medications simultaneously in the same patients. Our objective was to explore the efficacy of Tadalafil in CP/CPPS symptom management and whether co-administration of rectal Diazepam enhances potential benefit. A single-institution, retrospective chart review was performed on 63 adult males with CP/CPPS. NIH-Chronic Prostatitis Symptom Index (CPSI) questionnaires were collected before and after at least 45 days of treatment with either Tadalafil alone (n = 40) or Tadalafil with adjunctive Diazepam suppositories (n = 23). Both groups had similar baseline pain and urinary CPSI sub-scores, yet patients treated with Diazepam had significantly worse median quality of life sub-scores on both the initial (8.5 vs. 11, P = 0.01) and final (4 vs. 8.5 P = 0.02) surveys. For both groups, CPSI aggregated scores and pain, urinary, and quality of life sub-scores were significantly reduced compared to scores before treatment ( P < 0.0001-0.02). However, the reduction in symptom scores was not significantly different with the addition of Diazepam suppositories ( P = 0.47–0.94). Tadalafil, both with and without Diazepam, improved CP/CPPS symptom scores across all domains of the CPSI questionnaire. However, Diazepam suppositories do not confer additional benefit compared to Tadalafil therapy alone for CP/CPPS." @default.
- W4366333698 created "2023-04-20" @default.
- W4366333698 creator A5006030834 @default.
- W4366333698 creator A5016239224 @default.
- W4366333698 creator A5065674007 @default.
- W4366333698 creator A5069678653 @default.
- W4366333698 creator A5072994032 @default.
- W4366333698 creator A5081697572 @default.
- W4366333698 date "2023-04-18" @default.
- W4366333698 modified "2023-09-26" @default.
- W4366333698 title "Use of Adjuvant Rectal Diazepam with Oral Tadalafil for Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome" @default.
- W4366333698 cites W1978505438 @default.
- W4366333698 cites W1985296127 @default.
- W4366333698 cites W2009180477 @default.
- W4366333698 cites W2106179838 @default.
- W4366333698 cites W2111424249 @default.
- W4366333698 cites W2137852333 @default.
- W4366333698 cites W2167757606 @default.
- W4366333698 cites W2780183953 @default.
- W4366333698 cites W2800833953 @default.
- W4366333698 cites W3010748179 @default.
- W4366333698 cites W3038795413 @default.
- W4366333698 cites W3202405727 @default.
- W4366333698 doi "https://doi.org/10.21203/rs.3.rs-2814770/v1" @default.
- W4366333698 hasPublicationYear "2023" @default.
- W4366333698 type Work @default.
- W4366333698 citedByCount "0" @default.
- W4366333698 crossrefType "posted-content" @default.
- W4366333698 hasAuthorship W4366333698A5006030834 @default.
- W4366333698 hasAuthorship W4366333698A5016239224 @default.
- W4366333698 hasAuthorship W4366333698A5065674007 @default.
- W4366333698 hasAuthorship W4366333698A5069678653 @default.
- W4366333698 hasAuthorship W4366333698A5072994032 @default.
- W4366333698 hasAuthorship W4366333698A5081697572 @default.
- W4366333698 hasBestOaLocation W43663336981 @default.
- W4366333698 hasConcept C121608353 @default.
- W4366333698 hasConcept C126322002 @default.
- W4366333698 hasConcept C126894567 @default.
- W4366333698 hasConcept C141071460 @default.
- W4366333698 hasConcept C159110408 @default.
- W4366333698 hasConcept C1862650 @default.
- W4366333698 hasConcept C2776175493 @default.
- W4366333698 hasConcept C2776235491 @default.
- W4366333698 hasConcept C2776362571 @default.
- W4366333698 hasConcept C2779826273 @default.
- W4366333698 hasConcept C2779929075 @default.
- W4366333698 hasConcept C2779951463 @default.
- W4366333698 hasConcept C2780136519 @default.
- W4366333698 hasConcept C2780524745 @default.
- W4366333698 hasConcept C2780816001 @default.
- W4366333698 hasConcept C2781118164 @default.
- W4366333698 hasConcept C42219234 @default.
- W4366333698 hasConcept C71924100 @default.
- W4366333698 hasConcept C77411442 @default.
- W4366333698 hasConceptScore W4366333698C121608353 @default.
- W4366333698 hasConceptScore W4366333698C126322002 @default.
- W4366333698 hasConceptScore W4366333698C126894567 @default.
- W4366333698 hasConceptScore W4366333698C141071460 @default.
- W4366333698 hasConceptScore W4366333698C159110408 @default.
- W4366333698 hasConceptScore W4366333698C1862650 @default.
- W4366333698 hasConceptScore W4366333698C2776175493 @default.
- W4366333698 hasConceptScore W4366333698C2776235491 @default.
- W4366333698 hasConceptScore W4366333698C2776362571 @default.
- W4366333698 hasConceptScore W4366333698C2779826273 @default.
- W4366333698 hasConceptScore W4366333698C2779929075 @default.
- W4366333698 hasConceptScore W4366333698C2779951463 @default.
- W4366333698 hasConceptScore W4366333698C2780136519 @default.
- W4366333698 hasConceptScore W4366333698C2780524745 @default.
- W4366333698 hasConceptScore W4366333698C2780816001 @default.
- W4366333698 hasConceptScore W4366333698C2781118164 @default.
- W4366333698 hasConceptScore W4366333698C42219234 @default.
- W4366333698 hasConceptScore W4366333698C71924100 @default.
- W4366333698 hasConceptScore W4366333698C77411442 @default.
- W4366333698 hasLocation W43663336981 @default.
- W4366333698 hasOpenAccess W4366333698 @default.
- W4366333698 hasPrimaryLocation W43663336981 @default.
- W4366333698 hasRelatedWork W2038464024 @default.
- W4366333698 hasRelatedWork W2058376594 @default.
- W4366333698 hasRelatedWork W2273901552 @default.
- W4366333698 hasRelatedWork W2433616623 @default.
- W4366333698 hasRelatedWork W2598716865 @default.
- W4366333698 hasRelatedWork W2978113402 @default.
- W4366333698 hasRelatedWork W3147563318 @default.
- W4366333698 hasRelatedWork W4252724721 @default.
- W4366333698 hasRelatedWork W4366333698 @default.
- W4366333698 hasRelatedWork W2581219573 @default.
- W4366333698 isParatext "false" @default.
- W4366333698 isRetracted "false" @default.
- W4366333698 workType "article" @default.