FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366337513> ?p ?o ?g. }

• W4366337513 abstract "Abstract Abiotic stresses such as drought, salinity, and cold negatively affect plant growth and crop productivity. Understanding the molecular mechanisms underlying plant responses to these stressors is essential for stress tolerance in crops. The plant hormone abscisic acid (ABA) is significantly increased upon abiotic stressors, inducing physiological responses to adapt to stress and regulate gene expression. Although many studies have examined the components of established stress signaling pathways, few have explored other unknown elements. Data-driven studies have the advantage of analyzing large and independent datasets, which can lead to the identification of novel research topics. This study aimed to identify novel stress-responsive genes in plants by performing a meta-analysis of public RNA sequencing (RNA-Seq) data on Arabidopsis thaliana from the NCBI Gene Expression Omnibus, focusing on five ABA-related stress conditions (ABA, Salt, Dehydration, Osmotic, and Cold). The meta-analysis of 216 paired datasets from five stress conditions was conducted, and differentially expressed genes were identified by introducing a new metric, called TN (stress-treated (T) and non-treated (N))-score. Enrichment analysis was performed to characterize differentially expressed genes, and genes that were commonly regulated under different stresses were also identified. The meta-analysis revealed that 14 genes were commonly upregulated and 8 genes were commonly downregulated across all five treatments, including some that were not previously associated with these stress responses. On the other hand, some genes regulated by salt, dehydration, and osmotic treatments were not regulated by exogenous ABA or cold stress, suggesting that they may be involved in the plant response to dehydration independent of ABA. Meta-analysis revealed a list of candidate genes with unknown molecular mechanisms in ABA-dependent and ABA-independent stress responses. The identified genes could be valuable resources for selecting genome editing targets and potentially contribute to the discovery of novel stress tolerance mechanisms and pathways in plants." @default.
• W4366337513 created "2023-04-20" @default.
• W4366337513 creator A5000582879 @default.
• W4366337513 creator A5055742440 @default.
• W4366337513 creator A5079934306 @default.
• W4366337513 date "2023-04-18" @default.
• W4366337513 modified "2023-10-14" @default.
• W4366337513 title "Meta-Analysis of Public RNA Sequencing Data of Abscisic Acid-Related Abiotic Stresses in<i>Arabidopsis thaliana</i>" @default.
• W4366337513 cites W1967260680 @default.
• W4366337513 cites W1978289851 @default.
• W4366337513 cites W1990158242 @default.
• W4366337513 cites W2008547518 @default.
• W4366337513 cites W2036897871 @default.
• W4366337513 cites W2040811909 @default.
• W4366337513 cites W2060396596 @default.
• W4366337513 cites W2067026128 @default.
• W4366337513 cites W2096497715 @default.
• W4366337513 cites W2104720038 @default.
• W4366337513 cites W2105720010 @default.
• W4366337513 cites W2111094819 @default.
• W4366337513 cites W2118258530 @default.
• W4366337513 cites W2120768613 @default.
• W4366337513 cites W2124979541 @default.
• W4366337513 cites W2137981728 @default.
• W4366337513 cites W2142175676 @default.
• W4366337513 cites W2152972832 @default.
• W4366337513 cites W2153280526 @default.
• W4366337513 cites W2153409704 @default.
• W4366337513 cites W2158797945 @default.
• W4366337513 cites W2163657147 @default.
• W4366337513 cites W2167245757 @default.
• W4366337513 cites W2312880751 @default.
• W4366337513 cites W2332713712 @default.
• W4366337513 cites W2338823525 @default.
• W4366337513 cites W2345358281 @default.
• W4366337513 cites W2527891094 @default.
• W4366337513 cites W2551287024 @default.
• W4366337513 cites W2588422222 @default.
• W4366337513 cites W2592811885 @default.
• W4366337513 cites W2735379738 @default.
• W4366337513 cites W2793502838 @default.
• W4366337513 cites W2795084742 @default.
• W4366337513 cites W2799539649 @default.
• W4366337513 cites W2890634395 @default.
• W4366337513 cites W2954119161 @default.
• W4366337513 cites W2969287052 @default.
• W4366337513 cites W3003543135 @default.
• W4366337513 cites W3043027466 @default.
• W4366337513 cites W3043621295 @default.
• W4366337513 cites W3103191588 @default.
• W4366337513 cites W3105766949 @default.
• W4366337513 cites W3130392866 @default.
• W4366337513 cites W3130805890 @default.
• W4366337513 cites W3148962211 @default.
• W4366337513 cites W3164407807 @default.
• W4366337513 cites W4205472758 @default.
• W4366337513 cites W4213177269 @default.
• W4366337513 cites W4221125435 @default.
• W4366337513 cites W4280629577 @default.
• W4366337513 cites W4285795670 @default.
• W4366337513 cites W4296325264 @default.
• W4366337513 doi "https://doi.org/10.1101/2023.04.17.537107" @default.
• W4366337513 hasPublicationYear "2023" @default.
• W4366337513 type Work @default.
• W4366337513 citedByCount "0" @default.
• W4366337513 crossrefType "posted-content" @default.
• W4366337513 hasAuthorship W4366337513A5000582879 @default.
• W4366337513 hasAuthorship W4366337513A5055742440 @default.
• W4366337513 hasAuthorship W4366337513A5079934306 @default.
• W4366337513 hasBestOaLocation W43663375131 @default.
• W4366337513 hasConcept C104317684 @default.
• W4366337513 hasConcept C132215390 @default.
• W4366337513 hasConcept C143065580 @default.
• W4366337513 hasConcept C150194340 @default.
• W4366337513 hasConcept C168529131 @default.
• W4366337513 hasConcept C18903297 @default.
• W4366337513 hasConcept C2775988993 @default.
• W4366337513 hasConcept C2779491563 @default.
• W4366337513 hasConcept C2779591172 @default.
• W4366337513 hasConcept C54355233 @default.
• W4366337513 hasConcept C86803240 @default.
• W4366337513 hasConcept C89519541 @default.
• W4366337513 hasConceptScore W4366337513C104317684 @default.
• W4366337513 hasConceptScore W4366337513C132215390 @default.
• W4366337513 hasConceptScore W4366337513C143065580 @default.
• W4366337513 hasConceptScore W4366337513C150194340 @default.
• W4366337513 hasConceptScore W4366337513C168529131 @default.
• W4366337513 hasConceptScore W4366337513C18903297 @default.
• W4366337513 hasConceptScore W4366337513C2775988993 @default.
• W4366337513 hasConceptScore W4366337513C2779491563 @default.
• W4366337513 hasConceptScore W4366337513C2779591172 @default.
• W4366337513 hasConceptScore W4366337513C54355233 @default.
• W4366337513 hasConceptScore W4366337513C86803240 @default.
• W4366337513 hasConceptScore W4366337513C89519541 @default.
• W4366337513 hasLocation W43663375131 @default.
• W4366337513 hasOpenAccess W4366337513 @default.
• W4366337513 hasPrimaryLocation W43663375131 @default.
• W4366337513 hasRelatedWork W1985085986 @default.
• W4366337513 hasRelatedWork W1987361931 @default.
• W4366337513 hasRelatedWork W2052838235 @default.

• next