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• W4366338323 abstract "Abstract Objective To determine the prevalence of diabetic retinopathy (DR) and associated risk factors among rural and urban people living with diabetes mellitus (PwDM ) in southern China. Methods This cross-sectional study informed all the 3,646 PwDM aged > = 18 years in 2019. All were registered at primary health centers in Qujiang district. A questionnaire was administered to collect information on demographic, socioeconomic, medical and lifestyle factors. Blood glucose, lipids and indices of renal function were measured. Presence of DR was determined by trained graders based on fundus photographs using criteria of the United Kingdom National Health Service (NHS) Diabetic Eye Screening (DES) Programme. Multiple logistic regression analyses were used to assess potential risk factors for presence of DR. Results The mean age of the 2,677 participants (73.4%) was 63.4 years (SD 10.1 years), 1,503 (56.2%) were female, 1,749 (65.3%) were rural residents, 1,654 (71.0%) participants had HbA1c > = 6.5%, 1,773 (66.3%) had uncontrolled high blood pressure, and the median duration of DM was < 5 years. Although half (52.0%) of these participants had brief (< 5 years) exposure to DM, 831 (31.3%, 95% CI: 29.3–32.8%) had DR, among whom 412 (49.6%) had sight threatening DR. Men (33.1%), had a significantly higher prevalence of any DR than women (29.4%, p < 0.05). There were no significant differences in DR prevalence at any level between rural and urban residents. In multivariate regression models, risk factors for any DR were HbA1C > 6.5% (OR = 1.58 p < 0.01), using insulin and hypoglycemic drugs (OR = 1.76, p < 0.01), longer duration of DM and higher systolic blood pressure (OR = 1.01 for each mmHg, p < 0.01). Conclusion Although half of participants had DM for < 5 years, the high prevalence of DR, poorly controlled blood glucose and uncontrolled hypertension highlight the need for better management of non-communicable diseases in rural China." @default.
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• W4366338323 date "2023-04-18" @default.
• W4366338323 modified "2023-10-16" @default.
• W4366338323 title "Differences of prevalence and risk factors of diabetic retinopathy among rural and urban residents in South China" @default.
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• W4366338323 doi "https://doi.org/10.21203/rs.3.rs-2751558/v1" @default.
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