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• W4366351681 abstract "Pediatric Blood & CancerEarly View e30340 LETTER TO THE EDITOR B-cell lymphoblastic leukemia in an adolescent with Dravet syndrome Mohamed Alzobi, Mohamed Alzobi Department of Pediatric Hematology/Oncology & Stem Cell Transplantation, Cleveland Clinic, Cleveland, Ohio, USA Jordan University of Science and Technology, College of Medicine, Irbid, JordanSearch for more papers by this authorChristian Hurtz, Christian Hurtz Fels Cancer Institute for Personalized Medicine, Temple University, Philadelphia, Pennsylvania, USASearch for more papers by this authorHrishikesh Mehta, Hrishikesh Mehta Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USASearch for more papers by this authorStefanie Thomas, Stefanie Thomas Department of Pediatric Hematology/Oncology & Stem Cell Transplantation, Cleveland Clinic, Cleveland, Ohio, USASearch for more papers by this authorSeth J. Corey, Corresponding Author Seth J. Corey [email protected] orcid.org/0000-0002-3575-6401 Department of Pediatric Hematology/Oncology & Stem Cell Transplantation, Cleveland Clinic, Cleveland, Ohio, USA Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA Correspondence Seth Corey, Department of Pediatric Hematology/Oncology & Stem Cell Transplantation, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 441953, USA. Email: [email protected]Search for more papers by this author Mohamed Alzobi, Mohamed Alzobi Department of Pediatric Hematology/Oncology & Stem Cell Transplantation, Cleveland Clinic, Cleveland, Ohio, USA Jordan University of Science and Technology, College of Medicine, Irbid, JordanSearch for more papers by this authorChristian Hurtz, Christian Hurtz Fels Cancer Institute for Personalized Medicine, Temple University, Philadelphia, Pennsylvania, USASearch for more papers by this authorHrishikesh Mehta, Hrishikesh Mehta Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USASearch for more papers by this authorStefanie Thomas, Stefanie Thomas Department of Pediatric Hematology/Oncology & Stem Cell Transplantation, Cleveland Clinic, Cleveland, Ohio, USASearch for more papers by this authorSeth J. Corey, Corresponding Author Seth J. Corey [email protected] orcid.org/0000-0002-3575-6401 Department of Pediatric Hematology/Oncology & Stem Cell Transplantation, Cleveland Clinic, Cleveland, Ohio, USA Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA Correspondence Seth Corey, Department of Pediatric Hematology/Oncology & Stem Cell Transplantation, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 441953, USA. Email: [email protected]Search for more papers by this author First published: 19 April 2023 https://doi.org/10.1002/pbc.30340Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. REFERENCES 1Dravet C. The core Dravet syndrome phenotype. Epilepsia. 2011; 52(2): 3- 9. 2Catterall WA. Dravet syndrome: a sodium channel interneuronopathy. Curr Opin Physiol. 2018; 2: 42- 50. 3Huang CH, Hung PL, Fan PC, et al. Clinical spectrum and the comorbidities of Dravet syndrome in Taiwan and the possible molecular mechanisms. Sci Rep. 2021; 11(1):20242. 4Bagger FO, Kinalis S, Rapin N. BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles. Nucleic Acids Res. 2019; 47(D1): D881- D885. 5Harvey RC, Mullighan CG, Chen IM, et al. Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. Blood. 2010; 115(26): 5312- 5321. 6Cramer-Morales K, Nieborowska-Skorska M, Scheibner K, et al. Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile. Blood. 2013; 122(7): 1293- 1304. 7Antonucci R, Vacca N, Ghisu E, et al. Acute lymphoblastic leukemia in a nine-year-old girl with isodicentric chromosome 15 syndrome. Cancer Genet. 2019; 235-236: 93- 94. 8Chiang HL, Liu CJ, Hu YW, et al. Risk of cancer in children, adolescents, and young adults with autistic disorder. J Pediatr. 2015; 166(2): 418- 423.e1. 9Gannon WT, Martinez JE, Anderson SJ, Swingle HM. Cancer and copy number variants in an autism diagnostic clinic. J Dev Behav Pediatr. 2013; 34(5): 379- 381. 10Tyler CV, Schramm SC, Karafa M, Tang AS, Jain AK. Chronic disease risks in young adults with autism spectrum disorder: forewarned is forearmed. Am J Intellect Dev Disabil. 2011; 116(5): 371- 380. 11Blatt J, Deal AM, Mesibov G. Autism in children and adolescents with cancer. Pediatr Blood Cancer. 2010; 54(1): 144- 147. 12Vuattoux D, Colomer-Lahiguera S, Fernandez PA, et al. Cancer care of children, adolescents and adults with autism spectrum disorders: key information and strategies for oncology teams. Front Oncol. 2020; 10:595734. 13Wen Y, Herbert MR. Connecting the dots: overlaps between autism and cancer suggest possible common mechanisms regarding signaling pathways related to metabolic alterations. Med Hypotheses. 2017; 103: 118- 123. 14Liu DC, Eagleman DE, Tsai NP. Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation. PLoS Genet. 2019; 15(9):e1008364. 15Riahi-Zanjani B, Delirrad M, Fazeli-Bakhtiyari R, et al. Hematological consequences of valproic acid in pediatric patients: a systematic review with a mechanistic approach. CNS Neurol Disord Drug Targets. 2022; 21(4): 316- 325. 16Williams DC Jr, Massey GV, Russell EC, Riley RS, Ben-Ezra J. Translocation-positive acute myeloid leukemia associated with valproic acid therapy. Pediatr Blood Cancer. 2008; 50(3): 641- 643. Early ViewOnline Version of Record before inclusion in an issuee30340 ReferencesRelatedInformation" @default.
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