FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366351760> ?p ?o ?g. }

• W4366351760 endingPage "86" @default.
• W4366351760 startingPage "78" @default.
• W4366351760 abstract "OBJECTIVE This study examined differences in clinical and resuscitation characteristics between injured children with and without severe traumatic brain injury (sTBI) and aimed to identify resuscitation characteristics associated with improved outcomes following sTBI. METHODS This is a post hoc analysis of a prospective observational study of injured children younger than 18 years (2018–2019) transported from the scene, with elevated shock index pediatric-adjusted on arrival and head Abbreviated Injury Scale score of ≥3. Timing and volume of resuscitation products were assessed using χ 2 t test, Fisher's exact t test, Kruskal-Wallis, and multivariable logistic regression analyses. RESULTS There were 142 patients with sTBI and 547 with non-sTBI injuries. Severe traumatic brain injury patients had lower initial hemoglobin (11.3 vs. 12.4, p < 0.001), greater initial international normalized ratio (1.4 vs. 1.1, p < 0.001), greater Injury Severity Score (25 vs. 5, p < 0.001), greater rates of ventilator (59% vs. 11%, p < 0.001) and intensive care unit (ICU) requirement (79% vs. 27%, p < 0.001), and more inpatient complications (18% vs. 3.3%, p < 0.001). Severe traumatic brain injury patients received more prehospital crystalloid (25% vs. 15%, p = 0.008), ≥1 crystalloid boluses (52% vs. 24%, p < 0.001), and blood transfusion (44% vs. 12%, p < 0.001) than non-sTBI patients. Among sTBI patients, receipt of ≥1 crystalloid bolus (n = 75) was associated with greater ICU need (92% vs. 64%, p < 0.001), longer median ICU (6 vs. 4 days, p = 0.027) and hospital stay (9 vs. 4 days, p < 0.001), and more in-hospital complications (31% vs. 7.5%, p = 0.003) than those who received <1 bolus (n = 67). These findings persisted after adjustment for Injury Severity Score (odds ratio, 3.4–4.4; all p < 0.010). CONCLUSION Pediatric trauma patients with sTBI received more crystalloid than those without sTBI despite having a greater international normalized ratio at presentation and more frequently requiring blood products. Excessive crystalloid may be associated with worsened outcomes, including in-hospital mortality, seen among pediatric sTBI patients who received ≥1 crystalloid bolus. Further attention to a crystalloid sparing, early transfusion approach to resuscitation of children with sTBI is needed. LEVEL OF EVIDENCE Therapeutic/Care Management; Level IV." @default.
• W4366351760 created "2023-04-21" @default.
• W4366351760 creator A5002966813 @default.
• W4366351760 creator A5007948147 @default.
• W4366351760 creator A5010420590 @default.
• W4366351760 creator A5010783804 @default.
• W4366351760 creator A5011214722 @default.
• W4366351760 creator A5014513490 @default.
• W4366351760 creator A5015701297 @default.
• W4366351760 creator A5015835167 @default.
• W4366351760 creator A5017566240 @default.
• W4366351760 creator A5019951701 @default.
• W4366351760 creator A5022239099 @default.
• W4366351760 creator A5024710655 @default.
• W4366351760 creator A5026991318 @default.
• W4366351760 creator A5027705644 @default.
• W4366351760 creator A5029122228 @default.
• W4366351760 creator A5029506828 @default.
• W4366351760 creator A5037050761 @default.
• W4366351760 creator A5039676051 @default.
• W4366351760 creator A5039917528 @default.
• W4366351760 creator A5040725199 @default.
• W4366351760 creator A5043922024 @default.
• W4366351760 creator A5046547123 @default.
• W4366351760 creator A5050187438 @default.
• W4366351760 creator A5052263572 @default.
• W4366351760 creator A5055690957 @default.
• W4366351760 creator A5065739324 @default.
• W4366351760 creator A5067661058 @default.
• W4366351760 creator A5072010703 @default.
• W4366351760 creator A5074474037 @default.
• W4366351760 creator A5074594893 @default.
• W4366351760 creator A5075832808 @default.
• W4366351760 creator A5077331482 @default.
• W4366351760 creator A5077970012 @default.
• W4366351760 creator A5079571340 @default.
• W4366351760 creator A5082643021 @default.
• W4366351760 creator A5083091909 @default.
• W4366351760 creator A5086298203 @default.
• W4366351760 creator A5087626176 @default.
• W4366351760 creator A5084396634 @default.
• W4366351760 date "2023-04-19" @default.
• W4366351760 modified "2023-10-14" @default.
• W4366351760 title "Crystalloid volume is associated with short-term morbidity in children with severe traumatic brain injury: An Eastern Association for the Surgery of Trauma multicenter trial post hoc analysis" @default.
• W4366351760 cites W2016362244 @default.
• W4366351760 cites W2088239782 @default.
• W4366351760 cites W2165574572 @default.
• W4366351760 cites W2288959800 @default.
• W4366351760 cites W2334933140 @default.
• W4366351760 cites W2693139924 @default.
• W4366351760 cites W2790527919 @default.
• W4366351760 cites W2884498702 @default.
• W4366351760 cites W2946614609 @default.
• W4366351760 cites W2973472319 @default.
• W4366351760 cites W2987627344 @default.
• W4366351760 cites W3008200977 @default.
• W4366351760 cites W3014804760 @default.
• W4366351760 cites W3083603937 @default.
• W4366351760 cites W3085957096 @default.
• W4366351760 cites W3107387195 @default.
• W4366351760 cites W3126554123 @default.
• W4366351760 cites W3157780415 @default.
• W4366351760 cites W3178676525 @default.
• W4366351760 cites W4292722570 @default.
• W4366351760 doi "https://doi.org/10.1097/ta.0000000000004013" @default.
• W4366351760 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37072882" @default.
• W4366351760 hasPublicationYear "2023" @default.
• W4366351760 type Work @default.
• W4366351760 citedByCount "0" @default.
• W4366351760 crossrefType "journal-article" @default.
• W4366351760 hasAuthorship W4366351760A5002966813 @default.
• W4366351760 hasAuthorship W4366351760A5007948147 @default.
• W4366351760 hasAuthorship W4366351760A5010420590 @default.
• W4366351760 hasAuthorship W4366351760A5010783804 @default.
• W4366351760 hasAuthorship W4366351760A5011214722 @default.
• W4366351760 hasAuthorship W4366351760A5014513490 @default.
• W4366351760 hasAuthorship W4366351760A5015701297 @default.
• W4366351760 hasAuthorship W4366351760A5015835167 @default.
• W4366351760 hasAuthorship W4366351760A5017566240 @default.
• W4366351760 hasAuthorship W4366351760A5019951701 @default.
• W4366351760 hasAuthorship W4366351760A5022239099 @default.
• W4366351760 hasAuthorship W4366351760A5024710655 @default.
• W4366351760 hasAuthorship W4366351760A5026991318 @default.
• W4366351760 hasAuthorship W4366351760A5027705644 @default.
• W4366351760 hasAuthorship W4366351760A5029122228 @default.
• W4366351760 hasAuthorship W4366351760A5029506828 @default.
• W4366351760 hasAuthorship W4366351760A5037050761 @default.
• W4366351760 hasAuthorship W4366351760A5039676051 @default.
• W4366351760 hasAuthorship W4366351760A5039917528 @default.
• W4366351760 hasAuthorship W4366351760A5040725199 @default.
• W4366351760 hasAuthorship W4366351760A5043922024 @default.
• W4366351760 hasAuthorship W4366351760A5046547123 @default.
• W4366351760 hasAuthorship W4366351760A5050187438 @default.
• W4366351760 hasAuthorship W4366351760A5052263572 @default.
• W4366351760 hasAuthorship W4366351760A5055690957 @default.
• W4366351760 hasAuthorship W4366351760A5065739324 @default.
• W4366351760 hasAuthorship W4366351760A5067661058 @default.
• W4366351760 hasAuthorship W4366351760A5072010703 @default.

• next