Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366367056> ?p ?o ?g. }
- W4366367056 abstract "Ischemic stroke is a primary vascular disease of the central nervous system characterized by high morbidity, mortality, and healthcare costs. As conventional ischemic stroke models fail to predict therapeutic efficacy, in vitro neurovascular unit (NVU)/blood-brain barrier (BBB) models are utilized to model ischemic stroke through replicating the cell-cell interactions and mimicking the blood flow and anatomical features of the brain. Here, an overview of transwell, microfluidic, and hydrogel-based NVU/BBB models is provided, including cell types, engineering approaches, and the simulation of physiological and pathological features of NVU/BBB after ischemic stroke. Collectively, recent advances in 3D-printed NVU models are emphasized, which are anticipated to be a promising system for more reliable mechanistic studies and preclinical drug screenings that can eventually accelerate the drug development process for the ischemic stroke therapy." @default.
- W4366367056 created "2023-04-21" @default.
- W4366367056 creator A5016451976 @default.
- W4366367056 creator A5020141096 @default.
- W4366367056 creator A5028433300 @default.
- W4366367056 creator A5035126544 @default.
- W4366367056 creator A5044042665 @default.
- W4366367056 creator A5044901407 @default.
- W4366367056 creator A5076461268 @default.
- W4366367056 date "2023-05-01" @default.
- W4366367056 modified "2023-10-17" @default.
- W4366367056 title "Engineering Neurovascular Unit and Blood–Brain Barrier for Ischemic Stroke Modeling" @default.
- W4366367056 cites W1488563510 @default.
- W4366367056 cites W1837455343 @default.
- W4366367056 cites W1847104216 @default.
- W4366367056 cites W1968821998 @default.
- W4366367056 cites W1968873490 @default.
- W4366367056 cites W1970730429 @default.
- W4366367056 cites W1970803763 @default.
- W4366367056 cites W1974278626 @default.
- W4366367056 cites W1978208782 @default.
- W4366367056 cites W1982748428 @default.
- W4366367056 cites W1987305063 @default.
- W4366367056 cites W1990216374 @default.
- W4366367056 cites W1992866322 @default.
- W4366367056 cites W1994504773 @default.
- W4366367056 cites W1994812037 @default.
- W4366367056 cites W1998734023 @default.
- W4366367056 cites W1999866221 @default.
- W4366367056 cites W2001552996 @default.
- W4366367056 cites W2005445683 @default.
- W4366367056 cites W2005840555 @default.
- W4366367056 cites W2010418410 @default.
- W4366367056 cites W2010546163 @default.
- W4366367056 cites W2013520568 @default.
- W4366367056 cites W2015541518 @default.
- W4366367056 cites W2016211178 @default.
- W4366367056 cites W2019780808 @default.
- W4366367056 cites W2022334347 @default.
- W4366367056 cites W2024170393 @default.
- W4366367056 cites W2025652641 @default.
- W4366367056 cites W2029039324 @default.
- W4366367056 cites W2029939001 @default.
- W4366367056 cites W2030282028 @default.
- W4366367056 cites W2032148908 @default.
- W4366367056 cites W2039365659 @default.
- W4366367056 cites W2039414400 @default.
- W4366367056 cites W2041848964 @default.
- W4366367056 cites W2045228120 @default.
- W4366367056 cites W2045304765 @default.
- W4366367056 cites W2047075745 @default.
- W4366367056 cites W2047086401 @default.
- W4366367056 cites W2048329840 @default.
- W4366367056 cites W2050533098 @default.
- W4366367056 cites W2051140555 @default.
- W4366367056 cites W2051425293 @default.
- W4366367056 cites W2052578334 @default.
- W4366367056 cites W2056856515 @default.
- W4366367056 cites W2067349066 @default.
- W4366367056 cites W2067561254 @default.
- W4366367056 cites W2068337543 @default.
- W4366367056 cites W2073290778 @default.
- W4366367056 cites W2075262732 @default.
- W4366367056 cites W2077216169 @default.
- W4366367056 cites W2081135553 @default.
- W4366367056 cites W2089529899 @default.
- W4366367056 cites W2091559311 @default.
- W4366367056 cites W2091680093 @default.
- W4366367056 cites W2092530725 @default.
- W4366367056 cites W2093611661 @default.
- W4366367056 cites W2095298843 @default.
- W4366367056 cites W2096230518 @default.
- W4366367056 cites W2097760799 @default.
- W4366367056 cites W2098038342 @default.
- W4366367056 cites W2106454660 @default.
- W4366367056 cites W2107325549 @default.
- W4366367056 cites W2107527993 @default.
- W4366367056 cites W2107798346 @default.
- W4366367056 cites W2114789645 @default.
- W4366367056 cites W2117691576 @default.
- W4366367056 cites W2119851045 @default.
- W4366367056 cites W2125667096 @default.
- W4366367056 cites W2126231259 @default.
- W4366367056 cites W2133726488 @default.
- W4366367056 cites W2135290713 @default.
- W4366367056 cites W2144116792 @default.
- W4366367056 cites W2148992136 @default.
- W4366367056 cites W2152609612 @default.
- W4366367056 cites W2155436051 @default.
- W4366367056 cites W2157305235 @default.
- W4366367056 cites W2159888487 @default.
- W4366367056 cites W2162913942 @default.
- W4366367056 cites W2165059130 @default.
- W4366367056 cites W2171632655 @default.
- W4366367056 cites W2171784501 @default.
- W4366367056 cites W2172864295 @default.
- W4366367056 cites W2201221710 @default.
- W4366367056 cites W2259341484 @default.
- W4366367056 cites W2262503792 @default.
- W4366367056 cites W2277219084 @default.