Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366372020> ?p ?o ?g. }
- W4366372020 endingPage "365" @default.
- W4366372020 startingPage "354" @default.
- W4366372020 abstract "Since the recognition that mutations in components of the Wnt-β-catenin pathway underlie some human cancers, considerable attention has been dedicated to developing therapeutic modalities to block its activity. Despite numerous efforts, no drug directly inhibiting Wnt signaling is currently clinically available. Conversely, activating the Wnt pathway in a specific manner has recently been made possible with new molecules mimicking the activity of Wnt proteins, thus offering new possibilities for controlling tissue stem cell activity and for the rational treatment of various degenerative conditions. We describe the landscape of antibody modalities that modulate the Wnt-β-catenin pathway, and detail the advances and challenges in both cancer and regenerative medicine drug development." @default.
- W4366372020 created "2023-04-21" @default.
- W4366372020 creator A5035006305 @default.
- W4366372020 creator A5040025979 @default.
- W4366372020 creator A5053572781 @default.
- W4366372020 date "2023-06-01" @default.
- W4366372020 modified "2023-10-06" @default.
- W4366372020 title "Modulation of Wnt–β-catenin signaling with antibodies: therapeutic opportunities and challenges" @default.
- W4366372020 cites W1900557155 @default.
- W4366372020 cites W1965157206 @default.
- W4366372020 cites W1980222158 @default.
- W4366372020 cites W1980383179 @default.
- W4366372020 cites W1982603620 @default.
- W4366372020 cites W1994216131 @default.
- W4366372020 cites W1995665812 @default.
- W4366372020 cites W1996583924 @default.
- W4366372020 cites W2002725330 @default.
- W4366372020 cites W2029222627 @default.
- W4366372020 cites W2045936444 @default.
- W4366372020 cites W2057199920 @default.
- W4366372020 cites W2069750786 @default.
- W4366372020 cites W2075124840 @default.
- W4366372020 cites W2078040721 @default.
- W4366372020 cites W2078060536 @default.
- W4366372020 cites W2083457841 @default.
- W4366372020 cites W2084517025 @default.
- W4366372020 cites W2087560312 @default.
- W4366372020 cites W2090761100 @default.
- W4366372020 cites W2090789702 @default.
- W4366372020 cites W2096627331 @default.
- W4366372020 cites W2104176068 @default.
- W4366372020 cites W2119059014 @default.
- W4366372020 cites W2155040292 @default.
- W4366372020 cites W2163341100 @default.
- W4366372020 cites W2164479709 @default.
- W4366372020 cites W2166178545 @default.
- W4366372020 cites W2167380532 @default.
- W4366372020 cites W2174197315 @default.
- W4366372020 cites W2207864075 @default.
- W4366372020 cites W2258177869 @default.
- W4366372020 cites W2262448048 @default.
- W4366372020 cites W2518062514 @default.
- W4366372020 cites W2531652035 @default.
- W4366372020 cites W2553481980 @default.
- W4366372020 cites W2578928713 @default.
- W4366372020 cites W2599835027 @default.
- W4366372020 cites W2610869016 @default.
- W4366372020 cites W2620804290 @default.
- W4366372020 cites W2729843964 @default.
- W4366372020 cites W2754720807 @default.
- W4366372020 cites W2767868785 @default.
- W4366372020 cites W2891096931 @default.
- W4366372020 cites W2909312563 @default.
- W4366372020 cites W2909615207 @default.
- W4366372020 cites W2917980896 @default.
- W4366372020 cites W2922723892 @default.
- W4366372020 cites W2941492678 @default.
- W4366372020 cites W2945287782 @default.
- W4366372020 cites W2963099735 @default.
- W4366372020 cites W2970175551 @default.
- W4366372020 cites W2999505233 @default.
- W4366372020 cites W3012199016 @default.
- W4366372020 cites W3013678053 @default.
- W4366372020 cites W3025646024 @default.
- W4366372020 cites W3035819174 @default.
- W4366372020 cites W3049761941 @default.
- W4366372020 cites W3061588182 @default.
- W4366372020 cites W3082739207 @default.
- W4366372020 cites W3112648307 @default.
- W4366372020 cites W3115600179 @default.
- W4366372020 cites W3120378628 @default.
- W4366372020 cites W3168347719 @default.
- W4366372020 cites W3205550937 @default.
- W4366372020 cites W4200083183 @default.
- W4366372020 cites W4224869333 @default.
- W4366372020 cites W4280518206 @default.
- W4366372020 cites W4296808853 @default.
- W4366372020 cites W4315436679 @default.
- W4366372020 cites W4321492752 @default.
- W4366372020 doi "https://doi.org/10.1016/j.tips.2023.03.008" @default.
- W4366372020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37085400" @default.
- W4366372020 hasPublicationYear "2023" @default.
- W4366372020 type Work @default.
- W4366372020 citedByCount "2" @default.
- W4366372020 countsByYear W43663720202023 @default.
- W4366372020 crossrefType "journal-article" @default.
- W4366372020 hasAuthorship W4366372020A5035006305 @default.
- W4366372020 hasAuthorship W4366372020A5040025979 @default.
- W4366372020 hasAuthorship W4366372020A5053572781 @default.
- W4366372020 hasConcept C126322002 @default.
- W4366372020 hasConcept C137620995 @default.
- W4366372020 hasConcept C169760540 @default.
- W4366372020 hasConcept C30145163 @default.
- W4366372020 hasConcept C3019692148 @default.
- W4366372020 hasConcept C3020606620 @default.
- W4366372020 hasConcept C502942594 @default.
- W4366372020 hasConcept C62478195 @default.
- W4366372020 hasConcept C70721500 @default.