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- W4366396598 abstract "A solvent-dependent, divergent synthesis of highly functionalized N,S-heterocycles presenting a thiazoline and an isoquinuclidine (DCE as solvent) or tetrahydroisoquinoline (DMF as solvent) scaffolds by cyclization reactions of isoquinolinium 1,4-zwitterionic thiolates is reported. The robustness and applicability of the method are also demonstrated by an efficient 6-times upscaling of the reaction and derivatization of the thiazoline-isoquinuclidine derivatives." @default.
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- W4366396598 date "2023-01-01" @default.
- W4366396598 modified "2023-09-29" @default.
- W4366396598 title "Divergent access to fused <i>N</i>-heterocycle-thiazolines by solvent-dependent reaction of isoquinolinium thiolates with silylketene acetals" @default.
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- W4366396598 doi "https://doi.org/10.1039/d3cc00781b" @default.
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