Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366413089> ?p ?o ?g. }
- W4366413089 endingPage "60" @default.
- W4366413089 startingPage "52" @default.
- W4366413089 abstract "An in vitro study was conducted using a model of reconstituted human corneal epithelial (SkinEthic™ HCE/Human Corneal Epithelium) to test the modulation of cytokines secretion activity of Pomanox® (PMX), a standardized commercial extract of pomegranate fruit characterized by high punicalagin α + β content. Cell viability and inhibition of the release of interleukin-8 (IL-8) was evaluated in four conditions: negative control, positive inflammatory control with lipopolysaccharide (LPS) from Escherichia coli, positive anti-inflammatory control (LPS plus dexamethasone), and LPS plus PMX after 24 h of culture. The mean (±standard error of mean (SEM)) IL-8 level was 48.7 ± 5.1 pg/mL in the PMX condition vs. 172.7 ± 19.3 and 26.6 ± 1.2 in the LPS from E. coli and negative control, respectively (p < 0.05) and 93.8 ± 8.7 pg/mL in LPS plus dexamethasone (p = 0.165). The percentages of inhibition of IL-8 release were 45.7% for LPS plus dexamethasone and 63.8% for LPS plus PMX. The percentage of cell viability (86%) was also higher for the LPS plus PMX condition. The present findings add evidence to the anti-inflammatory effect of a PMX in an in vitro model of reconstituted corneal epithelial cells." @default.
- W4366413089 created "2023-04-21" @default.
- W4366413089 creator A5011018515 @default.
- W4366413089 creator A5048284072 @default.
- W4366413089 creator A5057512670 @default.
- W4366413089 creator A5061438829 @default.
- W4366413089 creator A5084569582 @default.
- W4366413089 date "2023-04-19" @default.
- W4366413089 modified "2023-10-05" @default.
- W4366413089 title "In Vitro Anti-Inflammatory Potential of Pomegranate Extract (Pomanox®) in a Reconstituted Human Corneal Epithelium Model" @default.
- W4366413089 cites W1483722796 @default.
- W4366413089 cites W1666216121 @default.
- W4366413089 cites W1969462547 @default.
- W4366413089 cites W1975990337 @default.
- W4366413089 cites W2005696027 @default.
- W4366413089 cites W2028057571 @default.
- W4366413089 cites W2042092530 @default.
- W4366413089 cites W2051770353 @default.
- W4366413089 cites W2054309532 @default.
- W4366413089 cites W2079544843 @default.
- W4366413089 cites W2083430194 @default.
- W4366413089 cites W2093549239 @default.
- W4366413089 cites W2095344941 @default.
- W4366413089 cites W2119492372 @default.
- W4366413089 cites W2174123198 @default.
- W4366413089 cites W2346306153 @default.
- W4366413089 cites W2510885295 @default.
- W4366413089 cites W2533820090 @default.
- W4366413089 cites W2547597635 @default.
- W4366413089 cites W2575521580 @default.
- W4366413089 cites W2743756645 @default.
- W4366413089 cites W2923778665 @default.
- W4366413089 cites W2970279627 @default.
- W4366413089 cites W2985008131 @default.
- W4366413089 cites W3002157461 @default.
- W4366413089 cites W3128916933 @default.
- W4366413089 cites W3131856678 @default.
- W4366413089 cites W3144096788 @default.
- W4366413089 cites W3161131517 @default.
- W4366413089 cites W3174498026 @default.
- W4366413089 cites W3177345173 @default.
- W4366413089 cites W3194860711 @default.
- W4366413089 cites W3212110004 @default.
- W4366413089 cites W3216743498 @default.
- W4366413089 cites W4200038615 @default.
- W4366413089 cites W4285743465 @default.
- W4366413089 cites W4293103875 @default.
- W4366413089 cites W4294162852 @default.
- W4366413089 cites W4307948032 @default.
- W4366413089 doi "https://doi.org/10.3390/jcto1020007" @default.
- W4366413089 hasPublicationYear "2023" @default.
- W4366413089 type Work @default.
- W4366413089 citedByCount "0" @default.
- W4366413089 crossrefType "journal-article" @default.
- W4366413089 hasAuthorship W4366413089A5011018515 @default.
- W4366413089 hasAuthorship W4366413089A5048284072 @default.
- W4366413089 hasAuthorship W4366413089A5057512670 @default.
- W4366413089 hasAuthorship W4366413089A5061438829 @default.
- W4366413089 hasAuthorship W4366413089A5084569582 @default.
- W4366413089 hasBestOaLocation W43664130891 @default.
- W4366413089 hasConcept C134018914 @default.
- W4366413089 hasConcept C142724271 @default.
- W4366413089 hasConcept C153911025 @default.
- W4366413089 hasConcept C185592680 @default.
- W4366413089 hasConcept C202751555 @default.
- W4366413089 hasConcept C203014093 @default.
- W4366413089 hasConcept C2776914184 @default.
- W4366413089 hasConcept C2778754761 @default.
- W4366413089 hasConcept C2779257441 @default.
- W4366413089 hasConcept C2780401358 @default.
- W4366413089 hasConcept C529295009 @default.
- W4366413089 hasConcept C53227056 @default.
- W4366413089 hasConcept C55493867 @default.
- W4366413089 hasConcept C68324877 @default.
- W4366413089 hasConcept C71924100 @default.
- W4366413089 hasConcept C86803240 @default.
- W4366413089 hasConcept C98274493 @default.
- W4366413089 hasConceptScore W4366413089C134018914 @default.
- W4366413089 hasConceptScore W4366413089C142724271 @default.
- W4366413089 hasConceptScore W4366413089C153911025 @default.
- W4366413089 hasConceptScore W4366413089C185592680 @default.
- W4366413089 hasConceptScore W4366413089C202751555 @default.
- W4366413089 hasConceptScore W4366413089C203014093 @default.
- W4366413089 hasConceptScore W4366413089C2776914184 @default.
- W4366413089 hasConceptScore W4366413089C2778754761 @default.
- W4366413089 hasConceptScore W4366413089C2779257441 @default.
- W4366413089 hasConceptScore W4366413089C2780401358 @default.
- W4366413089 hasConceptScore W4366413089C529295009 @default.
- W4366413089 hasConceptScore W4366413089C53227056 @default.
- W4366413089 hasConceptScore W4366413089C55493867 @default.
- W4366413089 hasConceptScore W4366413089C68324877 @default.
- W4366413089 hasConceptScore W4366413089C71924100 @default.
- W4366413089 hasConceptScore W4366413089C86803240 @default.
- W4366413089 hasConceptScore W4366413089C98274493 @default.
- W4366413089 hasIssue "2" @default.
- W4366413089 hasLocation W43664130891 @default.
- W4366413089 hasOpenAccess W4366413089 @default.
- W4366413089 hasPrimaryLocation W43664130891 @default.