Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366450295> ?p ?o ?g. }
- W4366450295 abstract "Abstract Conservation breeding programs have long been an important management tool for species recovery. Recently, breeding programs have begun to integrate next generation sequencing data into pedigree-based management strategies designed to maximize retention of genetic diversity and minimize inbreeding. The San Diego Zoo Wildlife Alliance established an ex situ breeding program for the endangered southern mountain yellow-legged frog ( Rana muscosa ), including two separately populations from the San Jacinto and San Bernardino mountain ranges. In this study, we conducted molecular population genetic assessments using double digest restriction site-associated DNA sequencing data to provide improved breeding recommendations for the managed R. muscosa populations. We found that genetic diversity of ex situ populations was relatively low (H O = 0.166–0.245) and population differentiation moderate (F ST = 0.29). Patterns of genetic structure of captive frogs supported the evolutionary divergence of individuals by mountain ranges in the wild, with limited gene flow. Relatedness estimates identified close relatives among the founders, and molecularly-derived kinship values were used to determine and rank suitable breeders to minimize population mean kinship. Management recommendations highlight the need for importing additional founders from the wild to enhance genetic diversity in the breeding program, as effective source for genetic restoration." @default.
- W4366450295 created "2023-04-22" @default.
- W4366450295 creator A5014085183 @default.
- W4366450295 creator A5019477045 @default.
- W4366450295 creator A5024564059 @default.
- W4366450295 creator A5039973322 @default.
- W4366450295 creator A5050264657 @default.
- W4366450295 creator A5062969080 @default.
- W4366450295 creator A5078480395 @default.
- W4366450295 date "2023-04-19" @default.
- W4366450295 modified "2023-09-27" @default.
- W4366450295 title "Integrating Genomics into the Genetic Management of the Endangered Mountain Yellow-Legged Frog" @default.
- W4366450295 cites W1538178305 @default.
- W4366450295 cites W1655609833 @default.
- W4366450295 cites W1853214468 @default.
- W4366450295 cites W1855982476 @default.
- W4366450295 cites W1893278325 @default.
- W4366450295 cites W1926302030 @default.
- W4366450295 cites W1984858514 @default.
- W4366450295 cites W2008319529 @default.
- W4366450295 cites W2010807578 @default.
- W4366450295 cites W2017935309 @default.
- W4366450295 cites W2021526151 @default.
- W4366450295 cites W2023236376 @default.
- W4366450295 cites W2027281024 @default.
- W4366450295 cites W2031856012 @default.
- W4366450295 cites W2035839217 @default.
- W4366450295 cites W2038282357 @default.
- W4366450295 cites W2040466877 @default.
- W4366450295 cites W2053898899 @default.
- W4366450295 cites W2062343749 @default.
- W4366450295 cites W2067715889 @default.
- W4366450295 cites W2075584929 @default.
- W4366450295 cites W2077062990 @default.
- W4366450295 cites W2098126593 @default.
- W4366450295 cites W2109326794 @default.
- W4366450295 cites W2112729257 @default.
- W4366450295 cites W2113916812 @default.
- W4366450295 cites W2115148249 @default.
- W4366450295 cites W2118422005 @default.
- W4366450295 cites W2120628313 @default.
- W4366450295 cites W2122284387 @default.
- W4366450295 cites W2122714144 @default.
- W4366450295 cites W2125092464 @default.
- W4366450295 cites W2131271579 @default.
- W4366450295 cites W2142306180 @default.
- W4366450295 cites W2148534663 @default.
- W4366450295 cites W2149992227 @default.
- W4366450295 cites W2150905832 @default.
- W4366450295 cites W2151260052 @default.
- W4366450295 cites W2152882637 @default.
- W4366450295 cites W2153850059 @default.
- W4366450295 cites W2154509098 @default.
- W4366450295 cites W2154733178 @default.
- W4366450295 cites W2159422098 @default.
- W4366450295 cites W2160015371 @default.
- W4366450295 cites W2161339576 @default.
- W4366450295 cites W2161901637 @default.
- W4366450295 cites W2162641775 @default.
- W4366450295 cites W2164325299 @default.
- W4366450295 cites W2169059205 @default.
- W4366450295 cites W2350556381 @default.
- W4366450295 cites W2395045630 @default.
- W4366450295 cites W2466245065 @default.
- W4366450295 cites W2537459485 @default.
- W4366450295 cites W2579579160 @default.
- W4366450295 cites W2617349321 @default.
- W4366450295 cites W2626908495 @default.
- W4366450295 cites W2756557004 @default.
- W4366450295 cites W2884074700 @default.
- W4366450295 cites W2892635007 @default.
- W4366450295 cites W2897004916 @default.
- W4366450295 cites W2900995858 @default.
- W4366450295 cites W2902767054 @default.
- W4366450295 cites W2911680648 @default.
- W4366450295 cites W2948225718 @default.
- W4366450295 cites W2979496116 @default.
- W4366450295 cites W2997715866 @default.
- W4366450295 cites W3007079053 @default.
- W4366450295 cites W3014703472 @default.
- W4366450295 cites W3015028202 @default.
- W4366450295 cites W3097899552 @default.
- W4366450295 cites W3098495126 @default.
- W4366450295 cites W3108732130 @default.
- W4366450295 cites W3138086094 @default.
- W4366450295 cites W3161731031 @default.
- W4366450295 cites W3162132570 @default.
- W4366450295 cites W3197965315 @default.
- W4366450295 cites W3201228937 @default.
- W4366450295 cites W3211189721 @default.
- W4366450295 cites W4244993900 @default.
- W4366450295 doi "https://doi.org/10.21203/rs.3.rs-2818860/v1" @default.
- W4366450295 hasPublicationYear "2023" @default.
- W4366450295 type Work @default.
- W4366450295 citedByCount "0" @default.
- W4366450295 crossrefType "posted-content" @default.
- W4366450295 hasAuthorship W4366450295A5014085183 @default.
- W4366450295 hasAuthorship W4366450295A5019477045 @default.
- W4366450295 hasAuthorship W4366450295A5024564059 @default.
- W4366450295 hasAuthorship W4366450295A5039973322 @default.