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• W4366451796 abstract "Abstract Background Long COVID is suggested to be present in 14 to 43% of COVID 19-survivors. Literature on this new condition states a need for a multidisciplinary approach including physical exercise and nutrition. The aim of the current UNLOCK study is to investigate the feasibility of the proposed protocol to prepare for a randomized controlled study that addresses the effectiveness of a personalized multimodal treatment compared to standard physiotherapy. Methods This is a protocol of a pragmatic, single-center, randomized controlled pilot trial with two groups. Patients with persisting symptoms related to a proven SARS-CoV-2 infection will be recruited from the Universitair Ziekenhuis Brussel, Belgium. Patients will receive either standard physiotherapy or an individualized physical exercise program combined with nutritional counseling. They will be followed-up at 6, 12 and 18 weeks after randomization. Discussion a multidisciplinary approach for dealing with long COVID is needed. Because of the lack of clear data and the fact that this is a very heterogenic group, we aim to prepare and optimize a randomized controlled study that addresses the effectiveness of a personalized multimodal treatment. Protocol version number and date Version number: 2.0 Version date: 10 June 2022 Trial registration: ClinicalTrials.gov Identifier: NCT05254301 (since February 24, 2022)" @default.
• W4366451796 created "2023-04-22" @default.
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• W4366451796 date "2023-04-19" @default.
• W4366451796 modified "2023-10-18" @default.
• W4366451796 title "Faster functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot study for a randomized, controlled single-center trial." @default.
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• W4366451796 doi "https://doi.org/10.21203/rs.3.rs-2392494/v1" @default.
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