FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366462904> ?p ?o ?g. }

• W4366462904 endingPage "1124" @default.
• W4366462904 startingPage "1116" @default.
• W4366462904 abstract "The world's human population is reaching record longevities. Consequently, our societies are experiencing the impacts of prolonged longevity, such as increased retirement age. A major hypothesized influence on aging patterns is resource limitation, formalized under calorie restriction (CR) theory. This theory predicts extended organismal longevity due to reduced calorie intake without malnutrition. However, several challenges face current CR research and, although several attempts have been made to overcome these challenges, there is still a lack of holistic understanding of how CR shapes organismal vitality. Here, we conduct a literature review of 224 CR peer-reviewed publications to summarize the state-of-the-art in the field. Using this summary, we highlight the challenges of CR research in our understanding of its impacts on longevity. We demonstrate that experimental research is biased toward short-lived species (98.2% of studies examine species with <5 years of mean life expectancy) and lacks realism in key areas, such as stochastic environments or interactions with other environmental drivers (eg, temperature). We argue that only by considering a range of short- and long-lived species and taking more realistic approaches, can CR impacts on longevity be examined and validated in natural settings. We conclude by proposing experimental designs and study species that will allow the discipline to gain much-needed understanding of how restricting caloric intake affects long-lived species in realistic settings. Through incorporating more experimental realism, we anticipate crucial insights that will ultimately shape the myriad of sociobioeconomic impacts of senescence in humans and other species across the Tree of Life." @default.
• W4366462904 created "2023-04-22" @default.
• W4366462904 creator A5004090194 @default.
• W4366462904 creator A5035883188 @default.
• W4366462904 creator A5036660301 @default.
• W4366462904 creator A5069697028 @default.
• W4366462904 creator A5079986486 @default.
• W4366462904 date "2023-04-20" @default.
• W4366462904 modified "2023-09-30" @default.
• W4366462904 title "The Hunger Games as the Key to Happily Ever After?" @default.
• W4366462904 cites W139423991 @default.
• W4366462904 cites W1510061121 @default.
• W4366462904 cites W1535272280 @default.
• W4366462904 cites W1550425703 @default.
• W4366462904 cites W1878348163 @default.
• W4366462904 cites W1901983160 @default.
• W4366462904 cites W1907648661 @default.
• W4366462904 cites W1966132436 @default.
• W4366462904 cites W1966778019 @default.
• W4366462904 cites W1980483991 @default.
• W4366462904 cites W1985335900 @default.
• W4366462904 cites W1993091967 @default.
• W4366462904 cites W1996018742 @default.
• W4366462904 cites W1998660601 @default.
• W4366462904 cites W2000224750 @default.
• W4366462904 cites W2002439310 @default.
• W4366462904 cites W2007285556 @default.
• W4366462904 cites W2007711341 @default.
• W4366462904 cites W2011052435 @default.
• W4366462904 cites W2014440105 @default.
• W4366462904 cites W2014504566 @default.
• W4366462904 cites W2015607124 @default.
• W4366462904 cites W2021469756 @default.
• W4366462904 cites W2024782183 @default.
• W4366462904 cites W2026398820 @default.
• W4366462904 cites W2033843550 @default.
• W4366462904 cites W2039254460 @default.
• W4366462904 cites W2043351010 @default.
• W4366462904 cites W2043545991 @default.
• W4366462904 cites W2044489610 @default.
• W4366462904 cites W2048800645 @default.
• W4366462904 cites W2051146267 @default.
• W4366462904 cites W2053379890 @default.
• W4366462904 cites W2053493267 @default.
• W4366462904 cites W2058444042 @default.
• W4366462904 cites W2062447017 @default.
• W4366462904 cites W2079186458 @default.
• W4366462904 cites W2080771607 @default.
• W4366462904 cites W2081397294 @default.
• W4366462904 cites W2081969319 @default.
• W4366462904 cites W2089997277 @default.
• W4366462904 cites W2095111708 @default.
• W4366462904 cites W2097952463 @default.
• W4366462904 cites W2098343475 @default.
• W4366462904 cites W2109299971 @default.
• W4366462904 cites W2117135051 @default.
• W4366462904 cites W2120193874 @default.
• W4366462904 cites W2125576474 @default.
• W4366462904 cites W2129103583 @default.
• W4366462904 cites W2130532337 @default.
• W4366462904 cites W2131639274 @default.
• W4366462904 cites W2133670262 @default.
• W4366462904 cites W2135858501 @default.
• W4366462904 cites W2137458142 @default.
• W4366462904 cites W2147205664 @default.
• W4366462904 cites W2148584459 @default.
• W4366462904 cites W2149856744 @default.
• W4366462904 cites W2150712568 @default.
• W4366462904 cites W2161955428 @default.
• W4366462904 cites W2163687810 @default.
• W4366462904 cites W2165912888 @default.
• W4366462904 cites W2192623030 @default.
• W4366462904 cites W2202911070 @default.
• W4366462904 cites W2216310786 @default.
• W4366462904 cites W2230528974 @default.
• W4366462904 cites W2238332245 @default.
• W4366462904 cites W2279416676 @default.
• W4366462904 cites W2294067750 @default.
• W4366462904 cites W2313362018 @default.
• W4366462904 cites W2461282777 @default.
• W4366462904 cites W2598304286 @default.
• W4366462904 cites W2605455618 @default.
• W4366462904 cites W2625380431 @default.
• W4366462904 cites W2735194946 @default.
• W4366462904 cites W2753972635 @default.
• W4366462904 cites W2779119057 @default.
• W4366462904 cites W2795818534 @default.
• W4366462904 cites W2796702487 @default.
• W4366462904 cites W2808313316 @default.
• W4366462904 cites W2922335671 @default.
• W4366462904 cites W2949472612 @default.
• W4366462904 cites W2958544637 @default.
• W4366462904 cites W2963958802 @default.
• W4366462904 cites W2969665462 @default.
• W4366462904 cites W3023875212 @default.
• W4366462904 cites W3025052811 @default.
• W4366462904 cites W3041430667 @default.
• W4366462904 cites W403088968 @default.

• next