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- W4366483092 abstract "Several fungal pathogens are becoming resistant to conventional fungal infection treatments, and some fungal pathogens have become multidrug-resistant. Alternative treatments include fungal vaccines, conventional or synthetic monoclonal antibody (mAb) injections, or potentially conventional or synthetic mAbs produced in vivo by injections of appropriately packaged mRNA. Specifically synthesized proteins can mask distinctive pathogenic fungal surface proteins and target pathogenic fungal proteins to stop fungal infections. Treatments could also use combinations of one or more antifungal drugs combined with direct injections or injections of packaged mRNA with instructions for patient synthesis of either the conventional or synthetic mAbs. These alternative treatments offer potentially significant advantages compared with existing treatments for fungal pathogens." @default.
- W4366483092 created "2023-04-22" @default.
- W4366483092 creator A5022644981 @default.
- W4366483092 date "2023-06-01" @default.
- W4366483092 modified "2023-09-23" @default.
- W4366483092 title "Treatment alternatives for multidrug-resistant fungal pathogens" @default.
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- W4366483092 doi "https://doi.org/10.1016/j.drudis.2023.103596" @default.
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