Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366490429> ?p ?o ?g. }
- W4366490429 endingPage "508.e10" @default.
- W4366490429 startingPage "508.e1" @default.
- W4366490429 abstract "Introduction/Background To determine the clinical significance of micropapillary urothelial carcinoma (MPUC) of the upper urinary tract (UTUC) and a potential therapeutic strategy. Patients and Methods A retrospective cohort study was conducted to examine the incidence of micropapillary UTUC from 2010 to 2018 and its clinicopathological characteristics. Clinical outcomes and cancer-specific survival (CSS) were compared between MPUC and conventional UTUC matched by stage within a 6-month variation of receiving surgery. Results A total of 24 MPUC cases were identified out of 901 cases (2.7%) of urothelial carcinoma (UC) of the renal pelvis and ureter. MPUC was significantly smaller (<3 cm) and associated with nodal metastasis compared with conventional UTUC (P = .017 & 0.021, respectively); however, no significant difference was observed for lymphovascular invasion, distant metastasis, or CSS (P > 0.50, respectively) compared with match controls. Six MPUC patients (25%) developed metastasis to the liver, lymph nodes, and lung during follow-up. Patients with HER2-positive MPUC (3 of 4) had a significantly higher risk of metastasis compared with HER2-negative MPUC (3 of 20; P = 0.035). Conclusions MPUC is an aggressive variant of UTUC and usually presents as a small locally advanced disease. HER2 immunohistochemistry may identify the subset of patients with micropapillary UTUC that are candidates for targeted therapy." @default.
- W4366490429 created "2023-04-22" @default.
- W4366490429 creator A5017683801 @default.
- W4366490429 creator A5019783237 @default.
- W4366490429 creator A5020109562 @default.
- W4366490429 creator A5034529425 @default.
- W4366490429 creator A5035509172 @default.
- W4366490429 creator A5039691082 @default.
- W4366490429 creator A5053980226 @default.
- W4366490429 creator A5057031286 @default.
- W4366490429 creator A5077110913 @default.
- W4366490429 creator A5080344577 @default.
- W4366490429 date "2023-08-01" @default.
- W4366490429 modified "2023-10-06" @default.
- W4366490429 title "Clinicopathologic Analysis of Micropapillary Urothelial Carcinoma of the Upper Urinary Tract: Implications for HER2-Targeted Therapy" @default.
- W4366490429 cites W1966004131 @default.
- W4366490429 cites W1977780578 @default.
- W4366490429 cites W1980840681 @default.
- W4366490429 cites W1981595528 @default.
- W4366490429 cites W1996689001 @default.
- W4366490429 cites W2015254345 @default.
- W4366490429 cites W2016508464 @default.
- W4366490429 cites W2024379672 @default.
- W4366490429 cites W2025049256 @default.
- W4366490429 cites W2037688980 @default.
- W4366490429 cites W2117178403 @default.
- W4366490429 cites W2135260024 @default.
- W4366490429 cites W2147810864 @default.
- W4366490429 cites W2160320035 @default.
- W4366490429 cites W2254688612 @default.
- W4366490429 cites W2297029953 @default.
- W4366490429 cites W2345994752 @default.
- W4366490429 cites W2473211312 @default.
- W4366490429 cites W2538604633 @default.
- W4366490429 cites W2791288590 @default.
- W4366490429 cites W2900982922 @default.
- W4366490429 cites W2903620351 @default.
- W4366490429 cites W2972076206 @default.
- W4366490429 cites W4232979217 @default.
- W4366490429 cites W4244946883 @default.
- W4366490429 cites W4377854801 @default.
- W4366490429 doi "https://doi.org/10.1016/j.clgc.2023.04.002" @default.
- W4366490429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37183125" @default.
- W4366490429 hasPublicationYear "2023" @default.
- W4366490429 type Work @default.
- W4366490429 citedByCount "0" @default.
- W4366490429 crossrefType "journal-article" @default.
- W4366490429 hasAuthorship W4366490429A5017683801 @default.
- W4366490429 hasAuthorship W4366490429A5019783237 @default.
- W4366490429 hasAuthorship W4366490429A5020109562 @default.
- W4366490429 hasAuthorship W4366490429A5034529425 @default.
- W4366490429 hasAuthorship W4366490429A5035509172 @default.
- W4366490429 hasAuthorship W4366490429A5039691082 @default.
- W4366490429 hasAuthorship W4366490429A5053980226 @default.
- W4366490429 hasAuthorship W4366490429A5057031286 @default.
- W4366490429 hasAuthorship W4366490429A5077110913 @default.
- W4366490429 hasAuthorship W4366490429A5080344577 @default.
- W4366490429 hasConcept C120665830 @default.
- W4366490429 hasConcept C121332964 @default.
- W4366490429 hasConcept C121608353 @default.
- W4366490429 hasConcept C126322002 @default.
- W4366490429 hasConcept C126894567 @default.
- W4366490429 hasConcept C143998085 @default.
- W4366490429 hasConcept C146357865 @default.
- W4366490429 hasConcept C151730666 @default.
- W4366490429 hasConcept C167135981 @default.
- W4366490429 hasConcept C2776664737 @default.
- W4366490429 hasConcept C2777521186 @default.
- W4366490429 hasConcept C2778065480 @default.
- W4366490429 hasConcept C2778740770 @default.
- W4366490429 hasConcept C2779013556 @default.
- W4366490429 hasConcept C2779909341 @default.
- W4366490429 hasConcept C2780352672 @default.
- W4366490429 hasConcept C2780824555 @default.
- W4366490429 hasConcept C2781230642 @default.
- W4366490429 hasConcept C2993461684 @default.
- W4366490429 hasConcept C3019882237 @default.
- W4366490429 hasConcept C61511704 @default.
- W4366490429 hasConcept C63363279 @default.
- W4366490429 hasConcept C71924100 @default.
- W4366490429 hasConcept C77411442 @default.
- W4366490429 hasConcept C86803240 @default.
- W4366490429 hasConceptScore W4366490429C120665830 @default.
- W4366490429 hasConceptScore W4366490429C121332964 @default.
- W4366490429 hasConceptScore W4366490429C121608353 @default.
- W4366490429 hasConceptScore W4366490429C126322002 @default.
- W4366490429 hasConceptScore W4366490429C126894567 @default.
- W4366490429 hasConceptScore W4366490429C143998085 @default.
- W4366490429 hasConceptScore W4366490429C146357865 @default.
- W4366490429 hasConceptScore W4366490429C151730666 @default.
- W4366490429 hasConceptScore W4366490429C167135981 @default.
- W4366490429 hasConceptScore W4366490429C2776664737 @default.
- W4366490429 hasConceptScore W4366490429C2777521186 @default.
- W4366490429 hasConceptScore W4366490429C2778065480 @default.
- W4366490429 hasConceptScore W4366490429C2778740770 @default.
- W4366490429 hasConceptScore W4366490429C2779013556 @default.
- W4366490429 hasConceptScore W4366490429C2779909341 @default.
- W4366490429 hasConceptScore W4366490429C2780352672 @default.