Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366548891> ?p ?o ?g. }
- W4366548891 endingPage "215" @default.
- W4366548891 startingPage "215" @default.
- W4366548891 abstract "Nitrite is a common pollutant encountered in aquaculture systems. During intensive hatchery, accumulation of nitrite can cause massive mortality of juvenile crustaceans. However, the nitrite toxicity and cellular stress responses in juvenile crustaceans is not clearly understood. Here, we investigate the survival, energy metabolism, and cellular stress responses in juvenile P. trituberculatus, an important aquaculture species in China, under acute nitrite stress. The results revealed nitrite resulted in a significant decrease in survival rate of juvenile swimming crab. After nitrite exposure, the activity of catabolic enzymes, such as HK, PK, CS, and CPT-1, were initially enhanced, and then they showed significant decrease at the late stage of exposure, accompanied by reduction in ATP and adenylate energy charge (AEC). The impaired energy homeostasis was possibly associated with disturbed AMPK signaling and enhanced anaerobic metabolism, which was indicated by the high levels of LDH activity and HIF-1α expression. Furthermore, we found that nitrite stress can depress antioxidant systems and unfold protein responses, causing oxidative damage and endoplasmic reticulum (ER) stress, and this, in turn, can trigger autophagy and apoptosis through both caspase-dependent and caspase-independent pathways. The results of the present study improve our understanding regarding adverse effects of nitrite on P. trituberculatus and provide valuable information for hatchery management." @default.
- W4366548891 created "2023-04-22" @default.
- W4366548891 creator A5007666269 @default.
- W4366548891 creator A5014882283 @default.
- W4366548891 creator A5021942270 @default.
- W4366548891 creator A5031501999 @default.
- W4366548891 creator A5052329648 @default.
- W4366548891 creator A5052436599 @default.
- W4366548891 creator A5052883326 @default.
- W4366548891 creator A5054710295 @default.
- W4366548891 creator A5055819576 @default.
- W4366548891 creator A5069972418 @default.
- W4366548891 date "2023-04-19" @default.
- W4366548891 modified "2023-10-17" @default.
- W4366548891 title "Survival, Energy Status, and Cellular Stress Responses of the Juvenile Swimming Crab Portunus trituberculatus under Acute Nitrite Stress" @default.
- W4366548891 cites W1608324899 @default.
- W4366548891 cites W1978499594 @default.
- W4366548891 cites W1982085282 @default.
- W4366548891 cites W1994823455 @default.
- W4366548891 cites W1995549957 @default.
- W4366548891 cites W2006569614 @default.
- W4366548891 cites W2010008722 @default.
- W4366548891 cites W2016040396 @default.
- W4366548891 cites W2017895446 @default.
- W4366548891 cites W2020243680 @default.
- W4366548891 cites W2026932288 @default.
- W4366548891 cites W2033838239 @default.
- W4366548891 cites W2036533390 @default.
- W4366548891 cites W2049239133 @default.
- W4366548891 cites W2057274775 @default.
- W4366548891 cites W2059367834 @default.
- W4366548891 cites W2060725618 @default.
- W4366548891 cites W2077390149 @default.
- W4366548891 cites W2085933321 @default.
- W4366548891 cites W2125756459 @default.
- W4366548891 cites W2171654757 @default.
- W4366548891 cites W2191330173 @default.
- W4366548891 cites W2317877264 @default.
- W4366548891 cites W2341268096 @default.
- W4366548891 cites W2396042100 @default.
- W4366548891 cites W2412953223 @default.
- W4366548891 cites W2466580765 @default.
- W4366548891 cites W2625887862 @default.
- W4366548891 cites W2763871199 @default.
- W4366548891 cites W2791589667 @default.
- W4366548891 cites W2897623138 @default.
- W4366548891 cites W2901059552 @default.
- W4366548891 cites W2910094410 @default.
- W4366548891 cites W2937346106 @default.
- W4366548891 cites W2970388774 @default.
- W4366548891 cites W2973009344 @default.
- W4366548891 cites W2980275734 @default.
- W4366548891 cites W3136026212 @default.
- W4366548891 cites W3215492853 @default.
- W4366548891 cites W4200201142 @default.
- W4366548891 cites W4210334975 @default.
- W4366548891 cites W4248136323 @default.
- W4366548891 cites W4292325249 @default.
- W4366548891 cites W4295007605 @default.
- W4366548891 cites W4306362386 @default.
- W4366548891 cites W4308157140 @default.
- W4366548891 cites W4315641869 @default.
- W4366548891 doi "https://doi.org/10.3390/fishes8040215" @default.
- W4366548891 hasPublicationYear "2023" @default.
- W4366548891 type Work @default.
- W4366548891 citedByCount "0" @default.
- W4366548891 crossrefType "journal-article" @default.
- W4366548891 hasAuthorship W4366548891A5007666269 @default.
- W4366548891 hasAuthorship W4366548891A5014882283 @default.
- W4366548891 hasAuthorship W4366548891A5021942270 @default.
- W4366548891 hasAuthorship W4366548891A5031501999 @default.
- W4366548891 hasAuthorship W4366548891A5052329648 @default.
- W4366548891 hasAuthorship W4366548891A5052436599 @default.
- W4366548891 hasAuthorship W4366548891A5052883326 @default.
- W4366548891 hasAuthorship W4366548891A5054710295 @default.
- W4366548891 hasAuthorship W4366548891A5055819576 @default.
- W4366548891 hasAuthorship W4366548891A5069972418 @default.
- W4366548891 hasBestOaLocation W43665488911 @default.
- W4366548891 hasConcept C18903297 @default.
- W4366548891 hasConcept C2776151105 @default.
- W4366548891 hasConcept C2776179834 @default.
- W4366548891 hasConcept C2776384668 @default.
- W4366548891 hasConcept C2778066766 @default.
- W4366548891 hasConcept C505870484 @default.
- W4366548891 hasConcept C55493867 @default.
- W4366548891 hasConcept C86803240 @default.
- W4366548891 hasConceptScore W4366548891C18903297 @default.
- W4366548891 hasConceptScore W4366548891C2776151105 @default.
- W4366548891 hasConceptScore W4366548891C2776179834 @default.
- W4366548891 hasConceptScore W4366548891C2776384668 @default.
- W4366548891 hasConceptScore W4366548891C2778066766 @default.
- W4366548891 hasConceptScore W4366548891C505870484 @default.
- W4366548891 hasConceptScore W4366548891C55493867 @default.
- W4366548891 hasConceptScore W4366548891C86803240 @default.
- W4366548891 hasFunder F4320321001 @default.
- W4366548891 hasFunder F4320335777 @default.
- W4366548891 hasFunder F4320338141 @default.
- W4366548891 hasIssue "4" @default.