FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366593809> ?p ?o ?g. }

• W4366593809 abstract "Background: Pancreatic cancer is one of the most deadly malignancies in the world. It is characterized by rapid progression and a very poor prognosis. The five-year survival rate of pancreatic cancer in China is only 7.2%, which is the lowest among all cancers and the use of combined paclitaxel albumin, capecitabine, and digital has been the clinical standard treatment for advanced pancreatic cancer since 1997. Also, the application of multidrug combinations is often limited by the toxicity of chemotherapy. Therefore, there is an urgent need for a more appropriate and less toxic treatment modality for pancreatic cancer. Case presentation: The patient was a 79-year-old woman, admitted to the hospital with a diagnosis of unresectable locally advanced pancreatic cancer (T3N0M0, stage IIA), with its imaging showing overgrowth of SMV involvement and unresectable reconstruction of the posterior vein after evaluation. As the patient refused chemotherapy, lenvatinib (8 mg/time, qd) and icaritin soft capsules (three tablets/time, bid) were recommended according to our past experience and a few clinical research cases. The tumor lesion was greatly reduced by 57.5% after the treatment, and the extent of vascular involvement also decreased. The aforementioned medication resulted in a significant downstaging of the patient's tumor. Conclusion: Better results were achieved in the treatment with icaritin soft capsules and lenvatinib in this case. Because of its less toxic effect on the liver and kidney and bone marrow suppression, it was suitable to combine icaritin soft capsules with targeted drugs for treating intermediate and advanced malignancies, which brings hope to patients who cannot or refuse to take chemotherapy." @default.
• W4366593809 created "2023-04-23" @default.
• W4366593809 creator A5002437958 @default.
• W4366593809 creator A5013475751 @default.
• W4366593809 creator A5044108258 @default.
• W4366593809 creator A5044201777 @default.
• W4366593809 creator A5047365731 @default.
• W4366593809 creator A5047737377 @default.
• W4366593809 date "2023-04-20" @default.
• W4366593809 modified "2023-10-14" @default.
• W4366593809 title "Case report: A case study on the treatment using icaritin soft capsules in combination with lenvatinib achieving impressive PR and stage reduction in unresectable locally progressive pancreatic cancer and a literature review" @default.
• W4366593809 cites W1494437451 @default.
• W4366593809 cites W1801994275 @default.
• W4366593809 cites W1994447535 @default.
• W4366593809 cites W2005231191 @default.
• W4366593809 cites W2017982140 @default.
• W4366593809 cites W2061355624 @default.
• W4366593809 cites W2095997161 @default.
• W4366593809 cites W2128095147 @default.
• W4366593809 cites W2128396846 @default.
• W4366593809 cites W2151600653 @default.
• W4366593809 cites W2152143404 @default.
• W4366593809 cites W2158134441 @default.
• W4366593809 cites W2159789252 @default.
• W4366593809 cites W2216813463 @default.
• W4366593809 cites W2753127414 @default.
• W4366593809 cites W2782317154 @default.
• W4366593809 cites W2808203586 @default.
• W4366593809 cites W2921145883 @default.
• W4366593809 cites W2941109595 @default.
• W4366593809 cites W2960253622 @default.
• W4366593809 cites W2970155667 @default.
• W4366593809 cites W2981288037 @default.
• W4366593809 cites W3013874260 @default.
• W4366593809 cites W3116521081 @default.
• W4366593809 cites W3139495897 @default.
• W4366593809 cites W3144501467 @default.
• W4366593809 cites W3157209351 @default.
• W4366593809 cites W3184820957 @default.
• W4366593809 cites W3192121286 @default.
• W4366593809 cites W3211658766 @default.
• W4366593809 cites W3216831771 @default.
• W4366593809 cites W4292833337 @default.
• W4366593809 doi "https://doi.org/10.3389/fgene.2023.1167470" @default.
• W4366593809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37152980" @default.
• W4366593809 hasPublicationYear "2023" @default.
• W4366593809 type Work @default.
• W4366593809 citedByCount "0" @default.
• W4366593809 crossrefType "journal-article" @default.
• W4366593809 hasAuthorship W4366593809A5002437958 @default.
• W4366593809 hasAuthorship W4366593809A5013475751 @default.
• W4366593809 hasAuthorship W4366593809A5044108258 @default.
• W4366593809 hasAuthorship W4366593809A5044201777 @default.
• W4366593809 hasAuthorship W4366593809A5047365731 @default.
• W4366593809 hasAuthorship W4366593809A5047737377 @default.
• W4366593809 hasBestOaLocation W43665938091 @default.
• W4366593809 hasConcept C121608353 @default.
• W4366593809 hasConcept C126322002 @default.
• W4366593809 hasConcept C141071460 @default.
• W4366593809 hasConcept C143998085 @default.
• W4366593809 hasConcept C146357865 @default.
• W4366593809 hasConcept C151730666 @default.
• W4366593809 hasConcept C2776264508 @default.
• W4366593809 hasConcept C2776581026 @default.
• W4366593809 hasConcept C2776694085 @default.
• W4366593809 hasConcept C2777909004 @default.
• W4366593809 hasConcept C2779761222 @default.
• W4366593809 hasConcept C2780210213 @default.
• W4366593809 hasConcept C526805850 @default.
• W4366593809 hasConcept C71924100 @default.
• W4366593809 hasConcept C86803240 @default.
• W4366593809 hasConceptScore W4366593809C121608353 @default.
• W4366593809 hasConceptScore W4366593809C126322002 @default.
• W4366593809 hasConceptScore W4366593809C141071460 @default.
• W4366593809 hasConceptScore W4366593809C143998085 @default.
• W4366593809 hasConceptScore W4366593809C146357865 @default.
• W4366593809 hasConceptScore W4366593809C151730666 @default.
• W4366593809 hasConceptScore W4366593809C2776264508 @default.
• W4366593809 hasConceptScore W4366593809C2776581026 @default.
• W4366593809 hasConceptScore W4366593809C2776694085 @default.
• W4366593809 hasConceptScore W4366593809C2777909004 @default.
• W4366593809 hasConceptScore W4366593809C2779761222 @default.
• W4366593809 hasConceptScore W4366593809C2780210213 @default.
• W4366593809 hasConceptScore W4366593809C526805850 @default.
• W4366593809 hasConceptScore W4366593809C71924100 @default.
• W4366593809 hasConceptScore W4366593809C86803240 @default.
• W4366593809 hasLocation W43665938091 @default.
• W4366593809 hasLocation W43665938092 @default.
• W4366593809 hasLocation W43665938093 @default.
• W4366593809 hasOpenAccess W4366593809 @default.
• W4366593809 hasPrimaryLocation W43665938091 @default.
• W4366593809 hasRelatedWork W167319750 @default.
• W4366593809 hasRelatedWork W1987468340 @default.
• W4366593809 hasRelatedWork W2139955290 @default.
• W4366593809 hasRelatedWork W2367812775 @default.
• W4366593809 hasRelatedWork W2388865264 @default.
• W4366593809 hasRelatedWork W2417717847 @default.
• W4366593809 hasRelatedWork W2419408601 @default.
• W4366593809 hasRelatedWork W2900510703 @default.
• W4366593809 hasRelatedWork W4240544598 @default.

• next