Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366607235> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4366607235 endingPage "102876" @default.
- W4366607235 startingPage "102876" @default.
- W4366607235 abstract "The discrete Laplace method can be used to estimate the frequency of a Y-chromosomal STR haplotype using a random sample from the population. Two limitations of the method are the assumptions that each profile has exactly one allele at every locus and that this allele has an integer repeat number. We relax these assumptions to allow for multi-copy loci, partial repeats and null alleles. We show how the parameters to the extension of the model can be estimated by numerical optimisation using an off-the-shelf solver. Concordance with the discrete Laplace method is obtained when the data satisfy the more stringent assumptions of the original method. We also investigate the performance of the (extended) discrete Laplace method when used to assign match probabilities for haplotypes. A simulation study shows that as more loci are used, match probabilities are underestimated more severely. This is consistent with the hypothesis that the discrete Laplace method cannot model the matches that arise by being identical by descent (IBD). As the number of loci increases the fraction of matches that are IBD increases. Simulation provides support that the discrete Laplace can model those matches that arise from identity by state (IBS) only." @default.
- W4366607235 created "2023-04-23" @default.
- W4366607235 creator A5015021900 @default.
- W4366607235 creator A5038210374 @default.
- W4366607235 creator A5056293288 @default.
- W4366607235 date "2023-07-01" @default.
- W4366607235 modified "2023-10-16" @default.
- W4366607235 title "Extending the discrete Laplace method: incorporating multi-copy loci, partial repeats and null alleles" @default.
- W4366607235 cites W2039921682 @default.
- W4366607235 cites W2122647159 @default.
- W4366607235 cites W2141811738 @default.
- W4366607235 cites W2148108289 @default.
- W4366607235 cites W2154188263 @default.
- W4366607235 cites W2160860891 @default.
- W4366607235 cites W2795521225 @default.
- W4366607235 cites W2883795241 @default.
- W4366607235 cites W2925359609 @default.
- W4366607235 cites W2941271880 @default.
- W4366607235 cites W2952968127 @default.
- W4366607235 cites W2997541073 @default.
- W4366607235 cites W3033048728 @default.
- W4366607235 cites W3048317303 @default.
- W4366607235 cites W3191595166 @default.
- W4366607235 cites W3199641586 @default.
- W4366607235 doi "https://doi.org/10.1016/j.fsigen.2023.102876" @default.
- W4366607235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37209602" @default.
- W4366607235 hasPublicationYear "2023" @default.
- W4366607235 type Work @default.
- W4366607235 citedByCount "0" @default.
- W4366607235 crossrefType "journal-article" @default.
- W4366607235 hasAuthorship W4366607235A5015021900 @default.
- W4366607235 hasAuthorship W4366607235A5038210374 @default.
- W4366607235 hasAuthorship W4366607235A5056293288 @default.
- W4366607235 hasConcept C104317684 @default.
- W4366607235 hasConcept C134306372 @default.
- W4366607235 hasConcept C144024400 @default.
- W4366607235 hasConcept C149923435 @default.
- W4366607235 hasConcept C178221405 @default.
- W4366607235 hasConcept C180754005 @default.
- W4366607235 hasConcept C197754878 @default.
- W4366607235 hasConcept C203763787 @default.
- W4366607235 hasConcept C22243797 @default.
- W4366607235 hasConcept C2908647359 @default.
- W4366607235 hasConcept C33923547 @default.
- W4366607235 hasConcept C41008148 @default.
- W4366607235 hasConcept C54355233 @default.
- W4366607235 hasConcept C77088390 @default.
- W4366607235 hasConcept C84597430 @default.
- W4366607235 hasConcept C86803240 @default.
- W4366607235 hasConcept C97937538 @default.
- W4366607235 hasConceptScore W4366607235C104317684 @default.
- W4366607235 hasConceptScore W4366607235C134306372 @default.
- W4366607235 hasConceptScore W4366607235C144024400 @default.
- W4366607235 hasConceptScore W4366607235C149923435 @default.
- W4366607235 hasConceptScore W4366607235C178221405 @default.
- W4366607235 hasConceptScore W4366607235C180754005 @default.
- W4366607235 hasConceptScore W4366607235C197754878 @default.
- W4366607235 hasConceptScore W4366607235C203763787 @default.
- W4366607235 hasConceptScore W4366607235C22243797 @default.
- W4366607235 hasConceptScore W4366607235C2908647359 @default.
- W4366607235 hasConceptScore W4366607235C33923547 @default.
- W4366607235 hasConceptScore W4366607235C41008148 @default.
- W4366607235 hasConceptScore W4366607235C54355233 @default.
- W4366607235 hasConceptScore W4366607235C77088390 @default.
- W4366607235 hasConceptScore W4366607235C84597430 @default.
- W4366607235 hasConceptScore W4366607235C86803240 @default.
- W4366607235 hasConceptScore W4366607235C97937538 @default.
- W4366607235 hasFunder F4320337430 @default.
- W4366607235 hasLocation W43666072351 @default.
- W4366607235 hasLocation W43666072352 @default.
- W4366607235 hasOpenAccess W4366607235 @default.
- W4366607235 hasPrimaryLocation W43666072351 @default.
- W4366607235 hasRelatedWork W1551477413 @default.
- W4366607235 hasRelatedWork W1982749768 @default.
- W4366607235 hasRelatedWork W1983642025 @default.
- W4366607235 hasRelatedWork W1996607800 @default.
- W4366607235 hasRelatedWork W2011656750 @default.
- W4366607235 hasRelatedWork W2049234958 @default.
- W4366607235 hasRelatedWork W2050081796 @default.
- W4366607235 hasRelatedWork W2087118228 @default.
- W4366607235 hasRelatedWork W2155294402 @default.
- W4366607235 hasRelatedWork W4234789023 @default.
- W4366607235 hasVolume "65" @default.
- W4366607235 isParatext "false" @default.
- W4366607235 isRetracted "false" @default.
- W4366607235 workType "article" @default.