FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366607241> ?p ?o ?g. }

• W4366607241 endingPage "108952" @default.
• W4366607241 startingPage "108952" @default.
• W4366607241 abstract "Studies were carried out on a novel bioreactor designed for the production of animal cells. The aim is, to provide 3D cell proliferation under the influence of low gravity together with gentle mixing and low shear stress. HepG2 cells were used in the experiments to show that this bioreactor can provide low shear forces and a micro-gravity effect considering the results from its Computational Flow Dynamics (CFD) analyses. This bioreactor design has a horizontally positioned cylindrical body and two U-shaped agitators placed opposite to each other. This opposing blade formation, has a reducing effect on each other's hydrodynamic forces and forms a region with low shear stress character in the center of the bioreactor. First of all, the hydrodynamic forces formed inside this bioreactor, which was designed on the basis of CFD simulations, were examined. Afterwards, this novel designed low shear horizontal bioreactor (LSB-R) was manufactured according to the CFD analysis, and simulations. Then, production trials were conducted to determine the success of LSB-R in spheroid production. Thus, by evaluating results obtained from the production trials in accordance with cell culture, it has been shown that LSB-R, which design and patenting phase has been completed, can provide low shear stress." @default.
• W4366607241 created "2023-04-23" @default.
• W4366607241 creator A5027930603 @default.
• W4366607241 creator A5055304155 @default.
• W4366607241 creator A5061376027 @default.
• W4366607241 creator A5075810438 @default.
• W4366607241 date "2023-07-01" @default.
• W4366607241 modified "2023-09-28" @default.
• W4366607241 title "A novel low shear horizontal bioreactor design for the production of animal cells: Effect of bioreactor dynamics on the 3D spheroid formation of HepG2" @default.
• W4366607241 cites W1508080975 @default.
• W4366607241 cites W1632817672 @default.
• W4366607241 cites W1965797625 @default.
• W4366607241 cites W1980080300 @default.
• W4366607241 cites W1980324695 @default.
• W4366607241 cites W1981684516 @default.
• W4366607241 cites W1986160959 @default.
• W4366607241 cites W2016008412 @default.
• W4366607241 cites W2017645555 @default.
• W4366607241 cites W2018073865 @default.
• W4366607241 cites W2032546095 @default.
• W4366607241 cites W2034285699 @default.
• W4366607241 cites W2046299552 @default.
• W4366607241 cites W2050384796 @default.
• W4366607241 cites W2050945798 @default.
• W4366607241 cites W2078024939 @default.
• W4366607241 cites W2083142606 @default.
• W4366607241 cites W2087022260 @default.
• W4366607241 cites W2091193164 @default.
• W4366607241 cites W2128846046 @default.
• W4366607241 cites W2141254815 @default.
• W4366607241 cites W2154555172 @default.
• W4366607241 cites W2159959435 @default.
• W4366607241 cites W2256377931 @default.
• W4366607241 cites W2321860791 @default.
• W4366607241 cites W2467332908 @default.
• W4366607241 cites W2568587776 @default.
• W4366607241 cites W2779100242 @default.
• W4366607241 cites W2794012367 @default.
• W4366607241 cites W2900904277 @default.
• W4366607241 cites W2901426632 @default.
• W4366607241 cites W2904056424 @default.
• W4366607241 cites W2908087216 @default.
• W4366607241 cites W2910432891 @default.
• W4366607241 cites W2995740978 @default.
• W4366607241 cites W3008811307 @default.
• W4366607241 cites W3092257792 @default.
• W4366607241 cites W3094678570 @default.
• W4366607241 cites W3123292433 @default.
• W4366607241 cites W3134222262 @default.
• W4366607241 cites W3135053723 @default.
• W4366607241 cites W4241579125 @default.
• W4366607241 doi "https://doi.org/10.1016/j.bej.2023.108952" @default.
• W4366607241 hasPublicationYear "2023" @default.
• W4366607241 type Work @default.
• W4366607241 citedByCount "0" @default.
• W4366607241 crossrefType "journal-article" @default.
• W4366607241 hasAuthorship W4366607241A5027930603 @default.
• W4366607241 hasAuthorship W4366607241A5055304155 @default.
• W4366607241 hasAuthorship W4366607241A5061376027 @default.
• W4366607241 hasAuthorship W4366607241A5075810438 @default.
• W4366607241 hasConcept C121332964 @default.
• W4366607241 hasConcept C127413603 @default.
• W4366607241 hasConcept C159985019 @default.
• W4366607241 hasConcept C1633027 @default.
• W4366607241 hasConcept C168170006 @default.
• W4366607241 hasConcept C178790620 @default.
• W4366607241 hasConcept C185592680 @default.
• W4366607241 hasConcept C192562407 @default.
• W4366607241 hasConcept C21141959 @default.
• W4366607241 hasConcept C22140971 @default.
• W4366607241 hasConcept C57879066 @default.
• W4366607241 hasConcept C66938386 @default.
• W4366607241 hasConcept C96035792 @default.
• W4366607241 hasConceptScore W4366607241C121332964 @default.
• W4366607241 hasConceptScore W4366607241C127413603 @default.
• W4366607241 hasConceptScore W4366607241C159985019 @default.
• W4366607241 hasConceptScore W4366607241C1633027 @default.
• W4366607241 hasConceptScore W4366607241C168170006 @default.
• W4366607241 hasConceptScore W4366607241C178790620 @default.
• W4366607241 hasConceptScore W4366607241C185592680 @default.
• W4366607241 hasConceptScore W4366607241C192562407 @default.
• W4366607241 hasConceptScore W4366607241C21141959 @default.
• W4366607241 hasConceptScore W4366607241C22140971 @default.
• W4366607241 hasConceptScore W4366607241C57879066 @default.
• W4366607241 hasConceptScore W4366607241C66938386 @default.
• W4366607241 hasConceptScore W4366607241C96035792 @default.
• W4366607241 hasFunder F4320322626 @default.
• W4366607241 hasLocation W43666072411 @default.
• W4366607241 hasOpenAccess W4366607241 @default.
• W4366607241 hasPrimaryLocation W43666072411 @default.
• W4366607241 hasRelatedWork W1531266123 @default.
• W4366607241 hasRelatedWork W1979068082 @default.
• W4366607241 hasRelatedWork W1984676160 @default.
• W4366607241 hasRelatedWork W1999111827 @default.
• W4366607241 hasRelatedWork W2013090897 @default.
• W4366607241 hasRelatedWork W2115798496 @default.
• W4366607241 hasRelatedWork W2498433176 @default.
• W4366607241 hasRelatedWork W2925305938 @default.

• next