Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366608436> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4366608436 abstract "Abstract Mediation analysis studies situations where an exposure may affect an outcome both directly and indirectly through intervening variables called mediators. It is frequently of interest to test for the effect of the exposure on the outcome, and the standard approach is simply to regress the latter on the former. However, it seems plausible that a more powerful test statistic could be achieved by also incorporating the mediators. This would be useful in cases where the exposure effect size might be small, which for example is common in genomics applications. Previous work has shown that this is indeed possible under complete mediation, where there is no direct effect. In most applications, however, the direct effect is likely nonzero. In this paper we study linear mediation models and find that under certain conditions, power gain is still possible under this incomplete mediation setting for testing the null hypothesis that there is neither a direct nor an indirect effect. We study a class of procedures that can achieve this performance and develop their application to both low- and high-dimensional mediators. We then illustrate their performances in simulations as well as in an analysis using DNA methylation mediators to study the effect of cigarette smoking on gene expression." @default.
- W4366608436 created "2023-04-23" @default.
- W4366608436 creator A5023194173 @default.
- W4366608436 creator A5048065488 @default.
- W4366608436 creator A5071172253 @default.
- W4366608436 date "2023-04-24" @default.
- W4366608436 modified "2023-10-18" @default.
- W4366608436 title "Power of testing for exposure effects under incomplete mediation" @default.
- W4366608436 cites W1715619412 @default.
- W4366608436 cites W1912093789 @default.
- W4366608436 cites W1929501557 @default.
- W4366608436 cites W1969936364 @default.
- W4366608436 cites W1976876708 @default.
- W4366608436 cites W1980991473 @default.
- W4366608436 cites W2006345816 @default.
- W4366608436 cites W2019139715 @default.
- W4366608436 cites W2019983262 @default.
- W4366608436 cites W2036672886 @default.
- W4366608436 cites W2037766829 @default.
- W4366608436 cites W2066669827 @default.
- W4366608436 cites W2069119359 @default.
- W4366608436 cites W2131185010 @default.
- W4366608436 cites W2134469398 @default.
- W4366608436 cites W2154972590 @default.
- W4366608436 cites W2155949904 @default.
- W4366608436 cites W2766173132 @default.
- W4366608436 cites W2768808579 @default.
- W4366608436 cites W2889418962 @default.
- W4366608436 cites W2941351579 @default.
- W4366608436 cites W2997938744 @default.
- W4366608436 cites W3023804329 @default.
- W4366608436 cites W3098193298 @default.
- W4366608436 cites W3099550161 @default.
- W4366608436 cites W3172837823 @default.
- W4366608436 cites W3191177528 @default.
- W4366608436 doi "https://doi.org/10.1515/ijb-2022-0106" @default.
- W4366608436 hasPublicationYear "2023" @default.
- W4366608436 type Work @default.
- W4366608436 citedByCount "0" @default.
- W4366608436 crossrefType "journal-article" @default.
- W4366608436 hasAuthorship W4366608436A5023194173 @default.
- W4366608436 hasAuthorship W4366608436A5048065488 @default.
- W4366608436 hasAuthorship W4366608436A5071172253 @default.
- W4366608436 hasConcept C105795698 @default.
- W4366608436 hasConcept C119043178 @default.
- W4366608436 hasConcept C144237770 @default.
- W4366608436 hasConcept C148220186 @default.
- W4366608436 hasConcept C149782125 @default.
- W4366608436 hasConcept C15744967 @default.
- W4366608436 hasConcept C169857963 @default.
- W4366608436 hasConcept C17744445 @default.
- W4366608436 hasConcept C179420905 @default.
- W4366608436 hasConcept C191988596 @default.
- W4366608436 hasConcept C199539241 @default.
- W4366608436 hasConcept C2776035688 @default.
- W4366608436 hasConcept C33923547 @default.
- W4366608436 hasConcept C41008148 @default.
- W4366608436 hasConcept C46312422 @default.
- W4366608436 hasConcept C87007009 @default.
- W4366608436 hasConcept C89128539 @default.
- W4366608436 hasConceptScore W4366608436C105795698 @default.
- W4366608436 hasConceptScore W4366608436C119043178 @default.
- W4366608436 hasConceptScore W4366608436C144237770 @default.
- W4366608436 hasConceptScore W4366608436C148220186 @default.
- W4366608436 hasConceptScore W4366608436C149782125 @default.
- W4366608436 hasConceptScore W4366608436C15744967 @default.
- W4366608436 hasConceptScore W4366608436C169857963 @default.
- W4366608436 hasConceptScore W4366608436C17744445 @default.
- W4366608436 hasConceptScore W4366608436C179420905 @default.
- W4366608436 hasConceptScore W4366608436C191988596 @default.
- W4366608436 hasConceptScore W4366608436C199539241 @default.
- W4366608436 hasConceptScore W4366608436C2776035688 @default.
- W4366608436 hasConceptScore W4366608436C33923547 @default.
- W4366608436 hasConceptScore W4366608436C41008148 @default.
- W4366608436 hasConceptScore W4366608436C46312422 @default.
- W4366608436 hasConceptScore W4366608436C87007009 @default.
- W4366608436 hasConceptScore W4366608436C89128539 @default.
- W4366608436 hasIssue "0" @default.
- W4366608436 hasLocation W43666084361 @default.
- W4366608436 hasLocation W43666084362 @default.
- W4366608436 hasOpenAccess W4366608436 @default.
- W4366608436 hasPrimaryLocation W43666084361 @default.
- W4366608436 hasRelatedWork W1565502317 @default.
- W4366608436 hasRelatedWork W2048035204 @default.
- W4366608436 hasRelatedWork W2102421359 @default.
- W4366608436 hasRelatedWork W2127561481 @default.
- W4366608436 hasRelatedWork W2185794042 @default.
- W4366608436 hasRelatedWork W2193982675 @default.
- W4366608436 hasRelatedWork W2949825100 @default.
- W4366608436 hasRelatedWork W3093005716 @default.
- W4366608436 hasRelatedWork W3123271271 @default.
- W4366608436 hasRelatedWork W3149298106 @default.
- W4366608436 hasVolume "0" @default.
- W4366608436 isParatext "false" @default.
- W4366608436 isRetracted "false" @default.
- W4366608436 workType "article" @default.