FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366608445> ?p ?o ?g. }

• W4366608445 endingPage "101947" @default.
• W4366608445 startingPage "101947" @default.
• W4366608445 abstract "Guidelines recommend routine frailty screening for all hospitalised older adults to inform care decisions, based mainly on studies in elective or speciality-specific settings. However, most hospital bed days are accounted for by acute non-elective admissions, in which the prevalence and prognostic value of frailty might differ, and uptake of screening is limited. We therefore did a systematic review and meta-analysis of frailty prevalence and outcomes in unplanned hospital admissions.We searched MEDLINE, EMBASE and CINAHL up to 31/01/2023 and included observational studies using validated frailty measures in adult hospital-wide or general medicine admissions. Summary data on the prevalence of frailty and associated outcomes, measurement tools, study setting (hospital-wide vs general medicine), and design (prospective vs retrospective) were extracted and risk of bias assessed (modified Joanna Briggs Institute checklists). Unadjusted relative risks (RR; moderate/severe frailty vs no/mild) for mortality (within one year), length of stay (LOS), discharge destination and readmission were calculated and pooled, where appropriate, using random-effects models. PROSPERO CRD42021235663.Among 45 cohorts (median/SD age = 80/5 years; n = 39,041,266 admissions, n = 22 measurement tools) moderate/severe frailty ranged from 14.3% to 79.6% overall (and in the 26 cohorts with low-moderate risk of bias) with considerable heterogeneity between studies (phet < 0.001) preventing pooling of results but with rates <25% in only 3 cohorts. Moderate/severe vs no/mild frailty was associated with increased mortality (n = 19 cohorts; RR range = 1.08-3.70), more consistently among cohorts using clinically administered tools (n = 11; RR range = 1.63-3.70; phet = 0.08; pooled RR = 2.53, 95% CI = 2.15-2.97) vs cohorts using (retrospective) administrative coding data (n = 8; RR range = 1.08-3.02; phet < 0.001). Clinically administered tools also predicted increasing mortality across the full range of frailty severity in each of the six cohorts that allowed ordinal analysis (all p < 0.05). Moderate/severe vs no/mild frailty was also associated with a LOS >8 days (RR range = 2.14-3.04; n = 6) and discharge to a location other than home (RR range = 1.97-2.82; n = 4) but was inconsistently related to 30-day readmission (RR range = 0.83-1.94; n = 12). Associations remained clinically significant after adjustment for age, sex and comorbidity where reported.Frailty is common in older patients with acute, non-elective hospital admission and remains predictive of mortality, LOS and discharge home with more severe frailty associated with greater risk, justifying more widespread implementation of screening using clinically administered tools.None." @default.
• W4366608445 created "2023-04-23" @default.
• W4366608445 creator A5014018674 @default.
• W4366608445 creator A5018531683 @default.
• W4366608445 creator A5055233202 @default.
• W4366608445 creator A5057600712 @default.
• W4366608445 creator A5069738985 @default.
• W4366608445 date "2023-05-01" @default.
• W4366608445 modified "2023-10-14" @default.
• W4366608445 title "Prevalence and outcomes of frailty in unplanned hospital admissions: a systematic review and meta-analysis of hospital-wide and general (internal) medicine cohorts" @default.
• W4366608445 cites W1717035664 @default.
• W4366608445 cites W1820823631 @default.
• W4366608445 cites W1969932369 @default.
• W4366608445 cites W1972916053 @default.
• W4366608445 cites W1973410407 @default.
• W4366608445 cites W1979900698 @default.
• W4366608445 cites W2006617902 @default.
• W4366608445 cites W2011155516 @default.
• W4366608445 cites W2022602281 @default.
• W4366608445 cites W2040329824 @default.
• W4366608445 cites W2044317148 @default.
• W4366608445 cites W2049003706 @default.
• W4366608445 cites W2059333369 @default.
• W4366608445 cites W2071199250 @default.
• W4366608445 cites W2085738590 @default.
• W4366608445 cites W2086923543 @default.
• W4366608445 cites W2095581666 @default.
• W4366608445 cites W2098898790 @default.
• W4366608445 cites W2100363874 @default.
• W4366608445 cites W2101659019 @default.
• W4366608445 cites W2105092978 @default.
• W4366608445 cites W2105781224 @default.
• W4366608445 cites W2118700087 @default.
• W4366608445 cites W2131348582 @default.
• W4366608445 cites W2133979095 @default.
• W4366608445 cites W2134833483 @default.
• W4366608445 cites W2151194188 @default.
• W4366608445 cites W2164059021 @default.
• W4366608445 cites W2164186760 @default.
• W4366608445 cites W2167748241 @default.
• W4366608445 cites W2173926371 @default.
• W4366608445 cites W2179355554 @default.
• W4366608445 cites W2179583309 @default.
• W4366608445 cites W2181051309 @default.
• W4366608445 cites W2290651480 @default.
• W4366608445 cites W2297632219 @default.
• W4366608445 cites W2394794694 @default.
• W4366608445 cites W2414995940 @default.
• W4366608445 cites W2416611083 @default.
• W4366608445 cites W2469248000 @default.
• W4366608445 cites W2507525628 @default.
• W4366608445 cites W2511776026 @default.
• W4366608445 cites W2538951137 @default.
• W4366608445 cites W2728404809 @default.
• W4366608445 cites W2739863292 @default.
• W4366608445 cites W2750715452 @default.
• W4366608445 cites W2762214859 @default.
• W4366608445 cites W2772711795 @default.
• W4366608445 cites W2790944889 @default.
• W4366608445 cites W2802067770 @default.
• W4366608445 cites W2806289232 @default.
• W4366608445 cites W2808312496 @default.
• W4366608445 cites W2885895637 @default.
• W4366608445 cites W2895188539 @default.
• W4366608445 cites W2898095381 @default.
• W4366608445 cites W2898834355 @default.
• W4366608445 cites W2902621836 @default.
• W4366608445 cites W2910962823 @default.
• W4366608445 cites W2923110332 @default.
• W4366608445 cites W2951781842 @default.
• W4366608445 cites W2952331461 @default.
• W4366608445 cites W2952537480 @default.
• W4366608445 cites W2964098696 @default.
• W4366608445 cites W2968475837 @default.
• W4366608445 cites W2972869830 @default.
• W4366608445 cites W2975424845 @default.
• W4366608445 cites W2975633737 @default.
• W4366608445 cites W2979434443 @default.
• W4366608445 cites W2990648940 @default.
• W4366608445 cites W2991899155 @default.
• W4366608445 cites W2995535927 @default.
• W4366608445 cites W3001477424 @default.
• W4366608445 cites W3010817785 @default.
• W4366608445 cites W3014283085 @default.
• W4366608445 cites W3049428677 @default.
• W4366608445 cites W3084393339 @default.
• W4366608445 cites W3086857220 @default.
• W4366608445 cites W3093385449 @default.
• W4366608445 cites W3110638412 @default.
• W4366608445 cites W3111631139 @default.
• W4366608445 cites W3121890798 @default.
• W4366608445 cites W3128915600 @default.
• W4366608445 cites W3132765077 @default.
• W4366608445 cites W3152353781 @default.
• W4366608445 cites W3154327349 @default.
• W4366608445 cites W3155522488 @default.
• W4366608445 cites W3175224701 @default.
• W4366608445 cites W3180727078 @default.

• next