Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366608843> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4366608843 endingPage "245" @default.
- W4366608843 startingPage "245" @default.
- W4366608843 abstract "Intellectual disability (ID) is a condition characterized by defective adaptive and cognitive attitude that can occur with various mental disorders, such as attention deficit/hyperactivity and autism spectrum disorder. It may also be associated with malformation syndromes affecting other organs. Genetic studies have linked several chromatin-modifying enzymes and epigenetic regulators to ID disorders (IDDs). This review explores how dysfunction in histone modifiers, chromatin remodelers, and methyl-DNA binding proteins can cause neurodevelopmental deformities and alter brain plasticity. The use of mouse models generated through human genetics has allowed researchers to uncover the molecular basis of ID and explore potential therapeutic strategies. Understanding the chromatin regulators associated with IDDs has broader implications for treating other IDDs, as they target common downstream genes and cellular functions. Investigating these disorders can also shed light on the function of chromatin regulators in brain growth, plasticity, and gene regulation, leading to new insights into fundamental questions in neurobiology." @default.
- W4366608843 created "2023-04-23" @default.
- W4366608843 creator A5001380569 @default.
- W4366608843 creator A5007083077 @default.
- W4366608843 creator A5007573618 @default.
- W4366608843 creator A5011453857 @default.
- W4366608843 creator A5023012453 @default.
- W4366608843 creator A5027185853 @default.
- W4366608843 creator A5032703069 @default.
- W4366608843 creator A5049752790 @default.
- W4366608843 creator A5057166200 @default.
- W4366608843 creator A5077919136 @default.
- W4366608843 creator A5080113647 @default.
- W4366608843 creator A5080376144 @default.
- W4366608843 date "2023-04-21" @default.
- W4366608843 modified "2023-10-17" @default.
- W4366608843 title "INTELLECTUAL DISABILITY CLASSIFICATION, CAUSES, EPIGENETIC MECHANISMS AND TREATMENT" @default.
- W4366608843 doi "https://doi.org/10.54112/bcsrj.v2023i1.245" @default.
- W4366608843 hasPublicationYear "2023" @default.
- W4366608843 type Work @default.
- W4366608843 citedByCount "0" @default.
- W4366608843 crossrefType "journal-article" @default.
- W4366608843 hasAuthorship W4366608843A5001380569 @default.
- W4366608843 hasAuthorship W4366608843A5007083077 @default.
- W4366608843 hasAuthorship W4366608843A5007573618 @default.
- W4366608843 hasAuthorship W4366608843A5011453857 @default.
- W4366608843 hasAuthorship W4366608843A5023012453 @default.
- W4366608843 hasAuthorship W4366608843A5027185853 @default.
- W4366608843 hasAuthorship W4366608843A5032703069 @default.
- W4366608843 hasAuthorship W4366608843A5049752790 @default.
- W4366608843 hasAuthorship W4366608843A5057166200 @default.
- W4366608843 hasAuthorship W4366608843A5077919136 @default.
- W4366608843 hasAuthorship W4366608843A5080113647 @default.
- W4366608843 hasAuthorship W4366608843A5080376144 @default.
- W4366608843 hasBestOaLocation W43666088431 @default.
- W4366608843 hasConcept C104317684 @default.
- W4366608843 hasConcept C118552586 @default.
- W4366608843 hasConcept C15744967 @default.
- W4366608843 hasConcept C167227067 @default.
- W4366608843 hasConcept C169760540 @default.
- W4366608843 hasConcept C205778803 @default.
- W4366608843 hasConcept C41091548 @default.
- W4366608843 hasConcept C47611674 @default.
- W4366608843 hasConcept C54355233 @default.
- W4366608843 hasConcept C551499885 @default.
- W4366608843 hasConcept C60644358 @default.
- W4366608843 hasConcept C64927066 @default.
- W4366608843 hasConcept C70721500 @default.
- W4366608843 hasConcept C83640560 @default.
- W4366608843 hasConcept C86803240 @default.
- W4366608843 hasConceptScore W4366608843C104317684 @default.
- W4366608843 hasConceptScore W4366608843C118552586 @default.
- W4366608843 hasConceptScore W4366608843C15744967 @default.
- W4366608843 hasConceptScore W4366608843C167227067 @default.
- W4366608843 hasConceptScore W4366608843C169760540 @default.
- W4366608843 hasConceptScore W4366608843C205778803 @default.
- W4366608843 hasConceptScore W4366608843C41091548 @default.
- W4366608843 hasConceptScore W4366608843C47611674 @default.
- W4366608843 hasConceptScore W4366608843C54355233 @default.
- W4366608843 hasConceptScore W4366608843C551499885 @default.
- W4366608843 hasConceptScore W4366608843C60644358 @default.
- W4366608843 hasConceptScore W4366608843C64927066 @default.
- W4366608843 hasConceptScore W4366608843C70721500 @default.
- W4366608843 hasConceptScore W4366608843C83640560 @default.
- W4366608843 hasConceptScore W4366608843C86803240 @default.
- W4366608843 hasIssue "1" @default.
- W4366608843 hasLocation W43666088431 @default.
- W4366608843 hasOpenAccess W4366608843 @default.
- W4366608843 hasPrimaryLocation W43666088431 @default.
- W4366608843 hasRelatedWork W1588926062 @default.
- W4366608843 hasRelatedWork W168279297 @default.
- W4366608843 hasRelatedWork W2000251389 @default.
- W4366608843 hasRelatedWork W2006158011 @default.
- W4366608843 hasRelatedWork W2172833929 @default.
- W4366608843 hasRelatedWork W2473903245 @default.
- W4366608843 hasRelatedWork W3097127970 @default.
- W4366608843 hasRelatedWork W4366608843 @default.
- W4366608843 hasRelatedWork W2184671570 @default.
- W4366608843 hasRelatedWork W3023895657 @default.
- W4366608843 hasVolume "2023" @default.
- W4366608843 isParatext "false" @default.
- W4366608843 isRetracted "false" @default.
- W4366608843 workType "article" @default.