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- W4366609008 abstract "A common basis to address the dynamics of directly transmitted infectious diseases, such as COVID-19, are compartmental (or SIR) models. SIR models typically assume homogenous population mixing, a simplification that is convenient but unrealistic. Here we validate an existing model of a scale-free fractal infection process using high-resolution data on COVID-19 spread in São Caetano, Brazil. We find that transmission can be described by a network in which each infectious individual has a small number of susceptible contacts, of the order of 2–5. This model parameter correlated tightly with physical distancing measured by mobile phone data, such that in periods of greater distancing the model recovered a lower average number of contacts, and vice versa. We show that the SIR model is a special case of our scale-free fractal process model in which the parameter that reflects population structure is set at unity, indicating homogeneous mixing. Our more general framework better explained the dynamics of COVID-19 in São Caetano, used fewer parameters than a standard SIR model and accounted for geographically localized clusters of disease. Our model requires further validation in other locations and with other directly transmitted infectious agents." @default.
- W4366609008 created "2023-04-23" @default.
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- W4366609008 date "2023-09-01" @default.
- W4366609008 modified "2023-09-28" @default.
- W4366609008 title "Scale-free dynamics of COVID-19 in a Brazilian city" @default.
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- W4366609008 doi "https://doi.org/10.1016/j.apm.2023.03.039" @default.
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