Matches in SemOpenAlex for { <https://semopenalex.org/work/W4366750930> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W4366750930 endingPage "154515" @default.
- W4366750930 startingPage "154515" @default.
- W4366750930 abstract "A decagram-scale synthesis of seven new building blocks of 1-oxaspiro[3.3]heptane family is described. This general approach requires 6 to 13 operationally simple steps starting from commercially available and inexpensive 3-oxocyclobutane-1-carboxylic acid. Expedient synthetic routes enable the straightforward access to these novel modules. Finally, the generation of virtual combinatorial library using the LLAMA software showed that building blocks described here demonstrated the high propensity to populate the lead-like chemical space. Like pigeons delivering letters, the newly 1-oxaspiro[3.3]heptane family scaffolds could deliver their functionality to drug-like compounds that are expected to be important in drug discovery and design." @default.
- W4366750930 created "2023-04-24" @default.
- W4366750930 creator A5029677359 @default.
- W4366750930 creator A5053078654 @default.
- W4366750930 date "2023-06-01" @default.
- W4366750930 modified "2023-09-30" @default.
- W4366750930 title "Synthesis of challenging 6-functionalized 1-oxaspiro[3.3]heptanes – New scaffolds for drug discovery" @default.
- W4366750930 cites W2014179609 @default.
- W4366750930 cites W2019737080 @default.
- W4366750930 cites W2027482274 @default.
- W4366750930 cites W2045665112 @default.
- W4366750930 cites W2074274985 @default.
- W4366750930 cites W2081851824 @default.
- W4366750930 cites W2083919220 @default.
- W4366750930 cites W2086066755 @default.
- W4366750930 cites W2088576798 @default.
- W4366750930 cites W2093751307 @default.
- W4366750930 cites W2101725657 @default.
- W4366750930 cites W2144570230 @default.
- W4366750930 cites W2147632720 @default.
- W4366750930 cites W2345702586 @default.
- W4366750930 cites W2519006730 @default.
- W4366750930 cites W2744309846 @default.
- W4366750930 cites W2771443936 @default.
- W4366750930 cites W2775830266 @default.
- W4366750930 cites W2910203594 @default.
- W4366750930 cites W2950334625 @default.
- W4366750930 cites W3017557605 @default.
- W4366750930 cites W3034046657 @default.
- W4366750930 cites W3088122612 @default.
- W4366750930 cites W3127703741 @default.
- W4366750930 cites W3166038843 @default.
- W4366750930 cites W3186402905 @default.
- W4366750930 cites W3187018092 @default.
- W4366750930 cites W3202040227 @default.
- W4366750930 cites W4205889056 @default.
- W4366750930 cites W4206343830 @default.
- W4366750930 cites W4283711376 @default.
- W4366750930 doi "https://doi.org/10.1016/j.tetlet.2023.154515" @default.
- W4366750930 hasPublicationYear "2023" @default.
- W4366750930 type Work @default.
- W4366750930 citedByCount "0" @default.
- W4366750930 crossrefType "journal-article" @default.
- W4366750930 hasAuthorship W4366750930A5029677359 @default.
- W4366750930 hasAuthorship W4366750930A5053078654 @default.
- W4366750930 hasBestOaLocation W43667509301 @default.
- W4366750930 hasConcept C103697762 @default.
- W4366750930 hasConcept C111472728 @default.
- W4366750930 hasConcept C118552586 @default.
- W4366750930 hasConcept C138885662 @default.
- W4366750930 hasConcept C15744967 @default.
- W4366750930 hasConcept C171250308 @default.
- W4366750930 hasConcept C178790620 @default.
- W4366750930 hasConcept C185592680 @default.
- W4366750930 hasConcept C192562407 @default.
- W4366750930 hasConcept C21951064 @default.
- W4366750930 hasConcept C2777854178 @default.
- W4366750930 hasConcept C2780035454 @default.
- W4366750930 hasConcept C2780586882 @default.
- W4366750930 hasConcept C55493867 @default.
- W4366750930 hasConcept C74187038 @default.
- W4366750930 hasConcept C99726746 @default.
- W4366750930 hasConceptScore W4366750930C103697762 @default.
- W4366750930 hasConceptScore W4366750930C111472728 @default.
- W4366750930 hasConceptScore W4366750930C118552586 @default.
- W4366750930 hasConceptScore W4366750930C138885662 @default.
- W4366750930 hasConceptScore W4366750930C15744967 @default.
- W4366750930 hasConceptScore W4366750930C171250308 @default.
- W4366750930 hasConceptScore W4366750930C178790620 @default.
- W4366750930 hasConceptScore W4366750930C185592680 @default.
- W4366750930 hasConceptScore W4366750930C192562407 @default.
- W4366750930 hasConceptScore W4366750930C21951064 @default.
- W4366750930 hasConceptScore W4366750930C2777854178 @default.
- W4366750930 hasConceptScore W4366750930C2780035454 @default.
- W4366750930 hasConceptScore W4366750930C2780586882 @default.
- W4366750930 hasConceptScore W4366750930C55493867 @default.
- W4366750930 hasConceptScore W4366750930C74187038 @default.
- W4366750930 hasConceptScore W4366750930C99726746 @default.
- W4366750930 hasFunder F4320324932 @default.
- W4366750930 hasFunder F4320330169 @default.
- W4366750930 hasLocation W43667509301 @default.
- W4366750930 hasOpenAccess W4366750930 @default.
- W4366750930 hasPrimaryLocation W43667509301 @default.
- W4366750930 hasRelatedWork W2184091110 @default.
- W4366750930 hasRelatedWork W2487343495 @default.
- W4366750930 hasRelatedWork W3102230098 @default.
- W4366750930 hasRelatedWork W3183930479 @default.
- W4366750930 hasRelatedWork W3185720802 @default.
- W4366750930 hasRelatedWork W3186878086 @default.
- W4366750930 hasRelatedWork W3211335638 @default.
- W4366750930 hasRelatedWork W4232045916 @default.
- W4366750930 hasRelatedWork W4241126451 @default.
- W4366750930 hasRelatedWork W4366750930 @default.
- W4366750930 hasVolume "122" @default.
- W4366750930 isParatext "false" @default.
- W4366750930 isRetracted "false" @default.
- W4366750930 workType "article" @default.